(18 nodes) Specification of animal organ identity network (Nomascus leucogenys)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

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Others

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protein homology

Your Input:
	TBR1-2	Uncharacterized protein. (231 aa)
	GLI3	GLI family zinc finger 3. (1502 aa)
	SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (478 aa)
	LRP2	LDL receptor related protein 2. (4624 aa)
	EXT1	Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (745 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
	ISL1	ISL LIM homeobox 1. (349 aa)
	FOXH1	Forkhead box H1. (366 aa)
	MESP1	Uncharacterized protein. (170 aa)
	BMP4	Bone morphogenetic protein 4. (408 aa)
	PAX2	Paired domain-containing protein. (385 aa)
	AXIN2	DIX domain-containing protein. (294 aa)
	WNT11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
	FGFR2	Fibroblast growth factor receptor. (820 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	ENSNLEP00000029616	RGS domain-containing protein. (169 aa)
	MEF2C	Myocyte enhancer factor 2C. (483 aa)
	TBR1	T-box_assoc domain-containing protein. (243 aa)

Your Current Organism:

Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AXIN2	BMP4	ENSNLEP00000018040	ENSNLEP00000015368	DIX domain-containing protein.	Bone morphogenetic protein 4.	0.451
AXIN2	ENSNLEP00000029616	ENSNLEP00000018040	ENSNLEP00000029616	DIX domain-containing protein.	RGS domain-containing protein.	0.887
AXIN2	LRP2	ENSNLEP00000018040	ENSNLEP00000005810	DIX domain-containing protein.	LDL receptor related protein 2.	0.461
AXIN2	WNT11	ENSNLEP00000018040	ENSNLEP00000020458	DIX domain-containing protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.559
AXIN2	WNT5A	ENSNLEP00000018040	ENSNLEP00000008828	DIX domain-containing protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.595
BMP4	AXIN2	ENSNLEP00000015368	ENSNLEP00000018040	Bone morphogenetic protein 4.	DIX domain-containing protein.	0.451
BMP4	FGF10	ENSNLEP00000015368	ENSNLEP00000029066	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.680
BMP4	FGFR2	ENSNLEP00000015368	ENSNLEP00000020533	Bone morphogenetic protein 4.	Fibroblast growth factor receptor.	0.511
BMP4	ISL1	ENSNLEP00000015368	ENSNLEP00000013061	Bone morphogenetic protein 4.	ISL LIM homeobox 1.	0.469
BMP4	PAX2	ENSNLEP00000015368	ENSNLEP00000017976	Bone morphogenetic protein 4.	Paired domain-containing protein.	0.448
BMP4	WNT11	ENSNLEP00000015368	ENSNLEP00000020458	Bone morphogenetic protein 4.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.419
BMP4	WNT5A	ENSNLEP00000015368	ENSNLEP00000008828	Bone morphogenetic protein 4.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.486
ENSNLEP00000029616	AXIN2	ENSNLEP00000029616	ENSNLEP00000018040	RGS domain-containing protein.	DIX domain-containing protein.	0.887
ENSNLEP00000029616	LRP2	ENSNLEP00000029616	ENSNLEP00000005810	RGS domain-containing protein.	LDL receptor related protein 2.	0.461
FGF10	BMP4	ENSNLEP00000029066	ENSNLEP00000015368	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Bone morphogenetic protein 4.	0.680
FGF10	FGFR2	ENSNLEP00000029066	ENSNLEP00000020533	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor receptor.	0.999
FGF10	GLI3	ENSNLEP00000029066	ENSNLEP00000003829	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	GLI family zinc finger 3.	0.464
FGFR2	BMP4	ENSNLEP00000020533	ENSNLEP00000015368	Fibroblast growth factor receptor.	Bone morphogenetic protein 4.	0.511
FGFR2	FGF10	ENSNLEP00000020533	ENSNLEP00000029066	Fibroblast growth factor receptor.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.999
FOXH1	MEF2C	ENSNLEP00000013159	ENSNLEP00000034337	Forkhead box H1.	Myocyte enhancer factor 2C.	0.494

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