57 items (Nomascus leucogenys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EGFR	Receptor protein-tyrosine kinase. (1206 aa)
	ENSNLEP00000035385	Prohibitin. (283 aa)
	ENSNLEP00000035153	Prohibitin. (261 aa)
	ADCYAP1R1	ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (500 aa)
	ENSNLEP00000030944	Prohibitin. (220 aa)
	ENSNLEP00000025813	Prohibitin. (188 aa)
	FGFR3	Receptor protein-tyrosine kinase. (583 aa)
	PTH	Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (115 aa)
	LPAR1	Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
	TXK	Tyrosine-protein kinase. (527 aa)
	AVPR1A	Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. (405 aa)
	FGFR2	Fibroblast growth factor receptor. (820 aa)
	RASGRP4	RAS guanyl releasing protein 4. (673 aa)
	PLAA	Phospholipase A2 activating protein. (764 aa)
	PLA2G1B	Phospholipase A(2). (148 aa)
	ABL2	Tyrosine-protein kinase. (1182 aa)
	ESR1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
	GNA13	G protein subunit alpha 13. (373 aa)
	CCL5	C-C motif chemokine. (91 aa)
	HPCAL1	Hippocalcin like 1. (193 aa)
	FGFR1	Fibroblast growth factor receptor. (835 aa)
	PDGFRB	Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
	PRKCZ	Protein kinase C zeta. (507 aa)
	CD86	CD86 molecule. (329 aa)
	AVPR1B	Vasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (426 aa)
	FLT1	Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa)
	PLCB2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1083 aa)
	GNAQ	G protein subunit alpha q. (358 aa)
	HPCA	Hippocalcin. (193 aa)
	PHB	Prohibitin. (272 aa)
	P2RY12	Purinergic receptor P2Y12. (342 aa)
	ITK	Tyrosine-protein kinase. (621 aa)
	PHB2	Prohibitin. (299 aa)
	EDNRA	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
	PLA2G5	Phospholipase A(2). (138 aa)
	HRAS	HRas proto-oncogene, GTPase. (189 aa)
	KIT	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (969 aa)
	LOC100592336	PH_3 domain-containing protein. (247 aa)
	PTAFR	Platelet activating factor receptor; Belongs to the G-protein coupled receptor 1 family. (342 aa)
	CCN1	Cellular communication network factor 1. (317 aa)
	ENSNLEP00000046375	Prohibitin. (169 aa)
	GNA15	G protein subunit alpha 15. (322 aa)
	ENSNLEP00000047903	Uncharacterized protein. (340 aa)
	ARHGAP6	Rho GTPase activating protein 6. (973 aa)
	LPAR2	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (297 aa)
	HTR2B	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (398 aa)
	ADRA1A	Adrenoceptor alpha 1A. (470 aa)
	AGTR1	Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family. (394 aa)
	ENSNLEP00000042917	Prohibitin. (131 aa)
	ENSNLEP00000042144	Prohibitin. (291 aa)
	P2RY6	Pyrimidinergic receptor P2Y6. (328 aa)
	LOC100593010	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (459 aa)
	NMUR1	Neuromedin U receptor 1. (412 aa)
	HTR2A	5-hydroxytryptamine receptor 2A. (471 aa)
	ARL1	ADP ribosylation factor like GTPase 1; Belongs to the small GTPase superfamily. Arf family. (164 aa)
	SELE	Selectin E. (612 aa)
	ENSNLEP00000037203	Prohibitin. (260 aa)

Your Current Organism:

Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL2	EGFR	ENSNLEP00000018934	ENSNLEP00000035792	Tyrosine-protein kinase.	Receptor protein-tyrosine kinase.	0.709
ADCYAP1R1	ENSNLEP00000047903	ENSNLEP00000031323	ENSNLEP00000047903	ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family.	Uncharacterized protein.	0.566
ADCYAP1R1	GNAQ	ENSNLEP00000031323	ENSNLEP00000003533	ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family.	G protein subunit alpha q.	0.566
ADCYAP1R1	PTH	ENSNLEP00000031323	ENSNLEP00000021470	ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family.	Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family.	0.515
ADRA1A	AVPR1A	ENSNLEP00000043808	ENSNLEP00000020752	Adrenoceptor alpha 1A.	Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system.	0.412
ADRA1A	ENSNLEP00000047903	ENSNLEP00000043808	ENSNLEP00000047903	Adrenoceptor alpha 1A.	Uncharacterized protein.	0.722
ADRA1A	GNA13	ENSNLEP00000043808	ENSNLEP00000018099	Adrenoceptor alpha 1A.	G protein subunit alpha 13.	0.972
ADRA1A	GNA15	ENSNLEP00000043808	ENSNLEP00000047095	Adrenoceptor alpha 1A.	G protein subunit alpha 15.	0.414
ADRA1A	GNAQ	ENSNLEP00000043808	ENSNLEP00000003533	Adrenoceptor alpha 1A.	G protein subunit alpha q.	0.971
ADRA1A	PLCB2	ENSNLEP00000043808	ENSNLEP00000003404	Adrenoceptor alpha 1A.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.413
AGTR1	AVPR1A	ENSNLEP00000043125	ENSNLEP00000020752	Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family.	Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system.	0.519
AGTR1	EDNRA	ENSNLEP00000043125	ENSNLEP00000006835	Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	0.520
AGTR1	EGFR	ENSNLEP00000043125	ENSNLEP00000035792	Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family.	Receptor protein-tyrosine kinase.	0.490
AGTR1	ENSNLEP00000047903	ENSNLEP00000043125	ENSNLEP00000047903	Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein.	0.807
AGTR1	GNA13	ENSNLEP00000043125	ENSNLEP00000018099	Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family.	G protein subunit alpha 13.	0.920
AGTR1	GNA15	ENSNLEP00000043125	ENSNLEP00000047095	Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family.	G protein subunit alpha 15.	0.488
AGTR1	GNAQ	ENSNLEP00000043125	ENSNLEP00000003533	Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family.	G protein subunit alpha q.	0.979
AGTR1	HTR2B	ENSNLEP00000043125	ENSNLEP00000048531	Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.437
AGTR1	LPAR1	ENSNLEP00000043125	ENSNLEP00000021217	Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family.	Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.921
AGTR1	LPAR2	ENSNLEP00000043125	ENSNLEP00000045220	Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.919

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