(45 nodes) Regulation of keratinocyte proliferation network (Nomascus leucogenys)

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second shell of interactors

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a 3D structure is known or predicted

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Predicted Interactions

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Your Input:
	CASK	Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (912 aa)
	ZEB1	Zinc finger E-box binding homeobox 1. (1105 aa)
	VDR	Vitamin D receptor. (427 aa)
	FGFR2	Fibroblast growth factor receptor. (820 aa)
	PTCH1	Patched 1. (1446 aa)
	LOC100607937	Uncharacterized protein. (600 aa)
	PRKD1	Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (832 aa)
	TGM1	Transglutaminase 1. (808 aa)
	ZFP36	ZFP36 ring finger protein. (322 aa)
	SNAI2	Snail family transcriptional repressor 2. (268 aa)
	CRNN	Cornulin. (495 aa)
	STXBP4	Syntaxin binding protein 4. (539 aa)
	IFT52	Intraflagellar transport 52. (396 aa)
	SRSF6	Serine and arginine rich splicing factor 6. (344 aa)
	FGF7	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
	OVOL1	Ovo like transcriptional repressor 1. (267 aa)
	NOTCH2	Notch receptor 2. (2444 aa)
	CDH3	Cadherin 3; Cadherins are calcium-dependent cell adhesion proteins. (829 aa)
	HAS2	Hyaluronan synthase 2. (552 aa)
	IFT172	Intraflagellar transport 172. (1703 aa)
	SFN	Stratifin; Belongs to the 14-3-3 family. (248 aa)
	SLURP1	Secreted LY6/PLAUR domain containing 1. (103 aa)
	REG3A	Regenerating family member 3 alpha. (175 aa)
	REG3G	Regenerating family member 3 gamma. (175 aa)
	ZFP36L1	ZFP36 ring finger protein like 1. (338 aa)
	MED1	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1558 aa)
	BCL11B	BAF chromatin remodeling complex subunit BCL11B. (864 aa)
	ENSNLEP00000045603	Uncharacterized protein. (252 aa)
	KLF9	Kruppel like factor 9. (244 aa)
	PTPRK	Protein tyrosine phosphatase receptor type K. (1416 aa)
	EFNB2	Ephrin B2; Belongs to the ephrin family. (299 aa)
	AREG	EGF-like domain-containing protein. (274 aa)
	INTU	Inturned planar cell polarity protein. (949 aa)
	IRF6	Interferon regulatory factor 6. (467 aa)
	ENSNLEP00000033551	Uncharacterized protein. (169 aa)
	ENSNLEP00000033330	Uncharacterized protein. (193 aa)
	TP63	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
	ENSNLEP00000032543	Uncharacterized protein. (168 aa)
	YAP1	Uncharacterized protein. (418 aa)
	CD109	CD109 molecule. (1405 aa)
	IFT80	Intraflagellar transport 80. (777 aa)
	LRG1	Leucine rich alpha-2-glycoprotein 1. (347 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	ENSNLEP00000027393	Uncharacterized protein. (308 aa)
	IFT57	Intraflagellar transport 57. (429 aa)

Your Current Organism:

Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AREG	FGF7	ENSNLEP00000040124	ENSNLEP00000007476	EGF-like domain-containing protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.513
AREG	FGFR2	ENSNLEP00000040124	ENSNLEP00000020533	EGF-like domain-containing protein.	Fibroblast growth factor receptor.	0.773
CASK	STXBP4	ENSNLEP00000002678	ENSNLEP00000009744	Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.	Syntaxin binding protein 4.	0.512
ENSNLEP00000032543	PTCH1	ENSNLEP00000032543	ENSNLEP00000020373	Uncharacterized protein.	Patched 1.	0.467
ENSNLEP00000032543	SFN	ENSNLEP00000032543	ENSNLEP00000022474	Uncharacterized protein.	Stratifin; Belongs to the 14-3-3 family.	0.737
ENSNLEP00000032543	SNAI2	ENSNLEP00000032543	ENSNLEP00000016248	Uncharacterized protein.	Snail family transcriptional repressor 2.	0.499
ENSNLEP00000032543	TP63	ENSNLEP00000032543	ENSNLEP00000032932	Uncharacterized protein.	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.	0.749
ENSNLEP00000032543	ZEB1	ENSNLEP00000032543	ENSNLEP00000022027	Uncharacterized protein.	Zinc finger E-box binding homeobox 1.	0.541
ENSNLEP00000033330	IFT172	ENSNLEP00000033330	ENSNLEP00000004557	Uncharacterized protein.	Intraflagellar transport 172.	0.913
ENSNLEP00000033330	IFT52	ENSNLEP00000033330	ENSNLEP00000007984	Uncharacterized protein.	Intraflagellar transport 52.	0.976
ENSNLEP00000033330	IFT57	ENSNLEP00000033330	ENSNLEP00000027391	Uncharacterized protein.	Intraflagellar transport 57.	0.969
ENSNLEP00000033330	IFT80	ENSNLEP00000033330	ENSNLEP00000029676	Uncharacterized protein.	Intraflagellar transport 80.	0.920
FGF10	FGF7	ENSNLEP00000029066	ENSNLEP00000007476	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.487
FGF10	FGFR2	ENSNLEP00000029066	ENSNLEP00000020533	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor receptor.	0.999
FGF7	AREG	ENSNLEP00000007476	ENSNLEP00000040124	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	EGF-like domain-containing protein.	0.513
FGF7	FGF10	ENSNLEP00000007476	ENSNLEP00000029066	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.487
FGF7	FGFR2	ENSNLEP00000007476	ENSNLEP00000020533	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor receptor.	0.998
FGFR2	AREG	ENSNLEP00000020533	ENSNLEP00000040124	Fibroblast growth factor receptor.	EGF-like domain-containing protein.	0.773
FGFR2	FGF10	ENSNLEP00000020533	ENSNLEP00000029066	Fibroblast growth factor receptor.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.999
FGFR2	FGF7	ENSNLEP00000020533	ENSNLEP00000007476	Fibroblast growth factor receptor.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.998

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