STRINGSTRING
ENSNLEP00000044067 ENSNLEP00000044067 SYT2 SYT2 LRRC1 LRRC1 PIP5K1C PIP5K1C UNC13A UNC13A CPLX3 CPLX3 SYT5 SYT5 PCLO PCLO RIMS1 RIMS1 UNC13B UNC13B SYT7 SYT7 UNC13C UNC13C ENSNLEP00000036861 ENSNLEP00000036861 ENSNLEP00000036455 ENSNLEP00000036455 SNAP23 SNAP23 STX1B STX1B DNAJC5 DNAJC5 STX1A STX1A SYNJ1 SYNJ1 PSEN1 PSEN1 STX3 STX3 PPFIA3 PPFIA3 SNAPIN SNAPIN PRRT2 PRRT2 SYT9 SYT9 STX4 STX4 P2RX7 P2RX7 STX11 STX11 SNAP25 SNAP25 SNCA SNCA SNAP47 SNAP47 SYT8 SYT8 RIMS3 RIMS3 CADPS2 CADPS2 CADPS CADPS SV2A SV2A CPLX4 CPLX4 STX2 STX2 DOC2A DOC2A ERC2 ERC2 SYT12 SYT12 RAB3A RAB3A BLOC1S6 BLOC1S6 NLGN1 NLGN1 SEPTIN5 SEPTIN5 CDK5 CDK5 RAP1A RAP1A RIMS2 RIMS2 OTOF OTOF BRAF BRAF SCRIB SCRIB CTBP2 CTBP2 CPLX2 CPLX2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSNLEP00000044067Uncharacterized protein. (108 aa)
SYT2Synaptotagmin 2. (419 aa)
LRRC1Leucine rich repeat containing 1. (503 aa)
PIP5K1CPIPK domain-containing protein. (759 aa)
UNC13AUnc-13 homolog A. (1460 aa)
CPLX3Complexin 3. (158 aa)
SYT5C2 domain-containing protein. (235 aa)
PCLOUncharacterized protein. (1217 aa)
RIMS1Regulating synaptic membrane exocytosis 1. (1637 aa)
UNC13BUncharacterized protein. (4218 aa)
SYT7Uncharacterized protein. (592 aa)
UNC13CC2 domain-containing protein. (135 aa)
ENSNLEP00000036861Uncharacterized protein. (119 aa)
ENSNLEP00000036455Uncharacterized protein. (127 aa)
SNAP23Synaptosomal-associated protein; Belongs to the SNAP-25 family. (211 aa)
STX1BSyntaxin 1B; Belongs to the syntaxin family. (293 aa)
DNAJC5DnaJ heat shock protein family (Hsp40) member C5. (198 aa)
STX1At-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (243 aa)
SYNJ1Synaptojanin 1. (1383 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
STX3Syntaxin 3; Belongs to the syntaxin family. (251 aa)
PPFIA3PTPRF interacting protein alpha 3. (1151 aa)
SNAPINSNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa)
PRRT2Proline rich transmembrane protein 2. (349 aa)
SYT9Synaptotagmin 9. (472 aa)
STX4Syntaxin 4; Belongs to the syntaxin family. (297 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
STX11Syntaxin 11; Belongs to the syntaxin family. (287 aa)
SNAP25Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
SNCAAlpha-synuclein; Belongs to the synuclein family. (140 aa)
SNAP47Synaptosome associated protein 47. (464 aa)
SYT8Synaptotagmin 8. (400 aa)
RIMS3Regulating synaptic membrane exocytosis 3. (308 aa)
CADPS2Calcium dependent secretion activator 2. (1297 aa)
CADPSUncharacterized protein. (1183 aa)
SV2ASynaptic vesicle glycoprotein 2A. (742 aa)
CPLX4Complexin 4. (160 aa)
STX2Syntaxin 2; Belongs to the syntaxin family. (287 aa)
DOC2ADouble C2 domain alpha. (355 aa)
ERC2ELKS/RAB6-interacting/CAST family member 2. (957 aa)
SYT12Synaptotagmin 12. (421 aa)
RAB3ARAB3A, member RAS oncogene family. (186 aa)
BLOC1S6Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...] (176 aa)
NLGN1Neuroligin 1. (823 aa)
SEPTIN5Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (323 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (320 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
RIMS2Uncharacterized protein. (1367 aa)
OTOFOtoferlin. (1968 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (764 aa)
SCRIBScribble planar cell polarity protein. (1449 aa)
CTBP2C-terminal binding protein 2. (957 aa)
CPLX2Complexin 2. (134 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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