STRINGSTRING
VPS26A VPS26A ATP6V0B ATP6V0B PRKACA PRKACA WDR24 WDR24 ENSNLEP00000025893 ENSNLEP00000025893 MAPK10 MAPK10 ATP6V1C2 ATP6V1C2 ENSNLEP00000027009 ENSNLEP00000027009 AKT1 AKT1 SNX30 SNX30 PIK3C3 PIK3C3 EXOC1 EXOC1 UVRAG UVRAG LOC100597720 LOC100597720 ENSNLEP00000031088 ENSNLEP00000031088 BNIP3 BNIP3 USP30 USP30 ATP13A2 ATP13A2 ENSNLEP00000032219 ENSNLEP00000032219 ENSNLEP00000032971 ENSNLEP00000032971 ENSNLEP00000033340 ENSNLEP00000033340 MTOR MTOR PIK3R4 PIK3R4 ENSNLEP00000036861 ENSNLEP00000036861 GPSM1 GPSM1 ATP6V1H ATP6V1H SNX5 SNX5 OPTN OPTN PAFAH1B2 PAFAH1B2 TSC2 TSC2 LACRT LACRT ENSNLEP00000039612 ENSNLEP00000039612 TIGAR TIGAR GNAI3 GNAI3 ENSNLEP00000041863 ENSNLEP00000041863 UCHL1 UCHL1 SUPT5H SUPT5H SCOC SCOC QSOX1 QSOX1 POLDIP2 POLDIP2 ENSNLEP00000043930 ENSNLEP00000043930 KDR KDR HMOX1 HMOX1 ATP6V1E1 ATP6V1E1 MAPK8 MAPK8 LOC100593029 LOC100593029 TECPR1 TECPR1 ENSNLEP00000047083 ENSNLEP00000047083 SPTLC2 SPTLC2 EHMT2 EHMT2 TRIM13 TRIM13 RUBCN RUBCN ENSNLEP00000047551 ENSNLEP00000047551 DCN DCN ENSNLEP00000047635 ENSNLEP00000047635 SESN3 SESN3 HIF1A HIF1A SLC25A4 SLC25A4 USP36 USP36 HSPB8 HSPB8 HTT HTT MTMR8 MTMR8 SPTLC1 SPTLC1 PIP4K2B PIP4K2B LZTS1 LZTS1 SNX4 SNX4 ATP6V1B2 ATP6V1B2 NOD2 NOD2 CLN3 CLN3 NUPR1 NUPR1 WIPI1 WIPI1 MAPK3 MAPK3 RIPK2 RIPK2 ATP6V0A2 ATP6V0A2 G1QNR4_NOMLE G1QNR4_NOMLE TMEM39B TMEM39B NRBP2 NRBP2 KIAA1324 KIAA1324 CDK5 CDK5 RHEB RHEB C9orf72 C9orf72 TMEM39A TMEM39A ATG2A ATG2A SMG1 SMG1 SEC22B SEC22B PIK3CA PIK3CA SNX32 SNX32 FYCO1 FYCO1 NEDD4 NEDD4 NPC1 NPC1 RUFY4 RUFY4 FEZ1 FEZ1 VDAC1 VDAC1 ULK1 ULK1 RAB3GAP1 RAB3GAP1 G1RD82_NOMLE G1RD82_NOMLE ATP6V0C ATP6V0C VPS13D VPS13D CHMP4B CHMP4B CLEC16A CLEC16A RNF41 RNF41 SNX7 SNX7 ATP6V0A1 ATP6V0A1 CAPNS1 CAPNS1 BECN1 BECN1 SIRT1 SIRT1 VPS13C VPS13C SESN1 SESN1 IL4 IL4 ATG14 ATG14 PIP4K2A PIP4K2A TSC1 TSC1 EXOC4 EXOC4 ATG5 ATG5 RAB3GAP2 RAB3GAP2 AMBRA1 AMBRA1 SMCR8 SMCR8 IKBKG IKBKG PRKAA2 PRKAA2 SLC25A5 SLC25A5 ERN1 ERN1 NOD1 NOD1 EPM2A EPM2A RNF31 RNF31 VPS35 VPS35 SCFD1 SCFD1 FEZ2 FEZ2 BNIP3L BNIP3L LARP1 LARP1 BAG3 BAG3 ATP6V1G1 ATP6V1G1 WAC WAC TBK1 TBK1 MOAP1 MOAP1 PIP4K2C PIP4K2C LRSAM1 LRSAM1 LRRK2 LRRK2 UBQLN2 UBQLN2 EXOC8 EXOC8 PINK1 PINK1 CALCOCO2 CALCOCO2 SESN2 SESN2 HDAC6 HDAC6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
VPS26AVPS26, retromer complex component A. (334 aa)
ATP6V0BUncharacterized protein; Belongs to the V-ATPase proteolipid subunit family. (258 aa)
PRKACAProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (294 aa)
WDR24WD repeat domain 24. (903 aa)
ENSNLEP00000025893Uncharacterized protein. (271 aa)
MAPK10Mitogen-activated protein kinase. (550 aa)
ATP6V1C2V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (361 aa)
ENSNLEP00000027009Uncharacterized protein. (249 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa)
SNX30Sorting nexin family member 30. (437 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (895 aa)
EXOC1Exocyst complex component 1. (901 aa)
UVRAGUV radiation resistance associated. (699 aa)
LOC100597720Uncharacterized protein. (278 aa)
ENSNLEP00000031088Protein kinase domain-containing protein. (557 aa)
BNIP3Uncharacterized protein. (231 aa)
USP30Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (500 aa)
ATP13A2Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1012 aa)
ENSNLEP00000032219V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (87 aa)
ENSNLEP00000032971Uncharacterized protein. (271 aa)
ENSNLEP00000033340Vps5 domain-containing protein. (249 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2578 aa)
PIK3R4Phosphoinositide-3-kinase regulatory subunit 4. (1358 aa)
ENSNLEP00000036861Uncharacterized protein. (119 aa)
GPSM1G protein signaling modulator 1. (701 aa)
ATP6V1HV-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (483 aa)
SNX5Sorting nexin; Involved in several stages of intracellular trafficking. (404 aa)
OPTNOptineurin. (577 aa)
PAFAH1B2Platelet activating factor acetylhydrolase 1b catalytic subunit 2. (229 aa)
TSC2TSC complex subunit 2. (1777 aa)
LACRTUncharacterized protein. (102 aa)
ENSNLEP00000039612Uncharacterized protein. (517 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (270 aa)
GNAI3G protein subunit alpha i3. (354 aa)
ENSNLEP00000041863SMG1_N domain-containing protein. (611 aa)
UCHL1Ubiquitin carboxyl-terminal hydrolase. (223 aa)
SUPT5HTranscription elongation factor SPT5. (1072 aa)
SCOCShort coiled-coil protein. (159 aa)
QSOX1Sulfhydryl oxidase. (739 aa)
POLDIP2DNA polymerase delta interacting protein 2. (368 aa)
ENSNLEP00000043930Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (265 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1367 aa)
HMOX1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (288 aa)
ATP6V1E1ATPase H+ transporting V1 subunit E1. (204 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
LOC100593029PX domain-containing protein. (372 aa)
TECPR1Tectonin beta-propeller repeat containing 1. (1162 aa)
ENSNLEP00000047083Uncharacterized protein. (267 aa)
SPTLC2Serine palmitoyltransferase long chain base subunit 2. (566 aa)
EHMT2Euchromatic histone lysine methyltransferase 2. (1122 aa)
TRIM13Tripartite motif containing 13. (410 aa)
RUBCNRubicon autophagy regulator. (966 aa)
ENSNLEP00000047551Uncharacterized protein. (553 aa)
DCNDecorin; May affect the rate of fibrils formation. (359 aa)
ENSNLEP00000047635Uncharacterized protein. (162 aa)
SESN3Sestrin 3. (520 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (850 aa)
SLC25A4Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (366 aa)
USP36Ubiquitin specific peptidase 36; Belongs to the peptidase C19 family. (1116 aa)
HSPB8Heat shock protein family B (small) member 8; Belongs to the small heat shock protein (HSP20) family. (196 aa)
HTTHuntingtin. (3048 aa)
MTMR8Myotubularin related protein 8. (704 aa)
SPTLC1Serine palmitoyltransferase long chain base subunit 1. (513 aa)
PIP4K2BPhosphatidylinositol-5-phosphate 4-kinase type 2 beta. (416 aa)
LZTS1Leucine zipper tumor suppressor 1. (589 aa)
SNX4Sorting nexin 4. (442 aa)
ATP6V1B2Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (528 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1040 aa)
CLN3Battenin. (384 aa)
NUPR1Nuclear protein 1, transcriptional regulator. (100 aa)
WIPI1WD repeat domain, phosphoinositide interacting 1. (419 aa)
MAPK3Mitogen-activated protein kinase. (278 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
ATP6V0A2V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (856 aa)
G1QNR4_NOMLEExocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (650 aa)
TMEM39BTransmembrane protein 39B. (525 aa)
NRBP2Nuclear receptor binding protein 2. (456 aa)
KIAA1324KIAA1324. (918 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (320 aa)
RHEBRas homolog, mTORC1 binding. (184 aa)
C9orf72Uncharacterized protein. (317 aa)
TMEM39ATransmembrane protein 39A. (476 aa)
ATG2AAutophagy related 2A. (1881 aa)
SMG1Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2477 aa)
SEC22BSEC22 homolog B, vesicle trafficking protein (gene/pseudogene); Belongs to the synaptobrevin family. (215 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
SNX32PX domain-containing protein. (327 aa)
FYCO1FYVE and coiled-coil domain containing 1. (1478 aa)
NEDD4NEDD4 E3 ubiquitin protein ligase. (1319 aa)
NPC1NPC intracellular cholesterol transporter 1. (1221 aa)
RUFY4RUN domain-containing protein. (466 aa)
FEZ1Fasciculation and elongation protein zeta 1. (392 aa)
VDAC1Voltage dependent anion channel 1. (282 aa)
ULK1Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. (1049 aa)
RAB3GAP1RAB3 GTPase activating protein catalytic subunit 1. (980 aa)
G1RD82_NOMLEUncharacterized protein. (342 aa)
ATP6V0CV-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
VPS13DVacuolar protein sorting 13 homolog D. (4387 aa)
CHMP4BCharged multivesicular body protein 4B. (224 aa)
CLEC16AC-type lectin domain containing 16A. (1043 aa)
RNF41Ring finger protein 41. (317 aa)
SNX7Sorting nexin 7. (451 aa)
ATP6V0A1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (825 aa)
CAPNS1Calpain small subunit 1. (264 aa)
BECN1Beclin 1. (450 aa)
SIRT1Sirtuin 1. (734 aa)
VPS13CVacuolar protein sorting 13 homolog C. (3745 aa)
SESN1Sestrin 1. (551 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (135 aa)
ATG14Autophagy related 14. (492 aa)
PIP4K2APhosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (371 aa)
TSC1TSC complex subunit 1. (1164 aa)
EXOC4Exocyst complex component 4. (974 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
RAB3GAP2RAB3 GTPase activating non-catalytic protein subunit 2. (1390 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1284 aa)
SMCR8SMCR8-C9orf72 complex subunit. (937 aa)
IKBKGNEMO domain-containing protein. (173 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
SLC25A5Solute carrier family 25 member 5; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (977 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (953 aa)
EPM2AEPM2A glucan phosphatase, laforin. (331 aa)
RNF31Uncharacterized protein. (1072 aa)
VPS35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (790 aa)
SCFD1Sec1 family domain containing 1; Belongs to the STXBP/unc-18/SEC1 family. (644 aa)
FEZ2Fasciculation and elongation protein zeta 2. (376 aa)
BNIP3LBCL2 interacting protein 3 like. (219 aa)
LARP1La ribonucleoprotein domain family member 1. (1007 aa)
BAG3BCL2 associated athanogene 3. (574 aa)
ATP6V1G1V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
WACWW domain containing adaptor with coiled-coil. (647 aa)
TBK1TANK binding kinase 1. (729 aa)
MOAP1Modulator of apoptosis 1. (351 aa)
PIP4K2CPhosphatidylinositol-5-phosphate 4-kinase type 2 gamma. (421 aa)
LRSAM1Leucine rich repeat and sterile alpha motif containing 1. (723 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
UBQLN2Ubiquilin 2. (624 aa)
EXOC8Exocyst complex component 8. (725 aa)
PINK1Protein kinase domain-containing protein. (563 aa)
CALCOCO2Calcium binding and coiled-coil domain 2. (470 aa)
SESN2Sestrin 2. (470 aa)
HDAC6Uncharacterized protein. (146 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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