STRINGSTRING
PRKCA PRKCA VRK1 VRK1 ACVR1 ACVR1 TAF1 TAF1 STK11 STK11 NLK NLK PRKD2 PRKD2 CAD CAD DYRK4 DYRK4 CSNK2A2 CSNK2A2 STK39 STK39 CDK5 CDK5 TGFBR2 TGFBR2 G1QVV6_NOMLE G1QVV6_NOMLE CDC42BPG CDC42BPG GRK2 GRK2 PRKCD PRKCD ULK1 ULK1 LOC100592336 LOC100592336 CSNK2A1 CSNK2A1 MYLK2 MYLK2 GSK3A GSK3A SBK1 SBK1 TTK TTK PRKDC PRKDC MAP3K10 MAP3K10 HIPK4 HIPK4 DYRK1B DYRK1B TSSK4 TSSK4 PRKD1 PRKD1 WNK3 WNK3 TBK1 TBK1 MAP3K12 MAP3K12 ACVR1B ACVR1B HIPK3 HIPK3 LRRK2 LRRK2 HASPIN HASPIN DYRK3 DYRK3 DYRK1A DYRK1A PRKACA PRKACA PKN1 PKN1 MAPK10 MAPK10 GSK3B GSK3B OXSR1 OXSR1 MAPK1 MAPK1 UMOD UMOD AKT1 AKT1 CDK1 CDK1 DCAF1 DCAF1 HIPK1 HIPK1 CLK1 CLK1 ATF2 ATF2 MTOR MTOR ROCK2 ROCK2 BCL2 BCL2 ENSNLEP00000036861 ENSNLEP00000036861 CIT CIT CDC42BPB CDC42BPB CDK10 CDK10 TNKS TNKS HIPK2 HIPK2 CAMK2D CAMK2D CHEK1 CHEK1 LOC100593010 LOC100593010 LMTK2 LMTK2 TGFBR1 TGFBR1 CAMK2A CAMK2A ROCK1 ROCK1 PRKCB PRKCB WNK1 WNK1 MAPK8 MAPK8 CDC42BPA CDC42BPA MARK2 MARK2 DYRK2 DYRK2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
VRK1VRK serine/threonine kinase 1; Belongs to the protein kinase superfamily. (396 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
TAF1TATA-box binding protein associated factor 1. (1767 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (423 aa)
NLKMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa)
PRKD2Uncharacterized protein. (716 aa)
CADCarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (2200 aa)
DYRK4Dual specificity tyrosine phosphorylation regulated kinase 4. (520 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (320 aa)
STK39Serine/threonine kinase 39. (507 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (320 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
G1QVV6_NOMLEProtein kinase domain-containing protein. (695 aa)
CDC42BPGCDC42 binding protein kinase gamma; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1471 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (589 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
ULK1Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. (1049 aa)
LOC100592336PH_3 domain-containing protein. (247 aa)
CSNK2A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa)
MYLK2Myosin light chain kinase 2. (596 aa)
GSK3AGlycogen synthase kinase 3 alpha. (439 aa)
SBK1Serine/threonine-protein kinase SBK1; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (424 aa)
TTKTTK protein kinase. (852 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit. (3853 aa)
MAP3K10Protein kinase domain-containing protein. (689 aa)
HIPK4Homeodomain interacting protein kinase 4. (564 aa)
DYRK1BProtein kinase domain-containing protein. (528 aa)
TSSK4Testis specific serine kinase 4. (337 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (832 aa)
WNK3WNK lysine deficient protein kinase 3. (1800 aa)
TBK1TANK binding kinase 1. (729 aa)
MAP3K12Mitogen-activated protein kinase kinase kinase 12. (747 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (498 aa)
HIPK3Homeodomain interacting protein kinase 3. (1215 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
HASPINHistone H3 associated protein kinase. (790 aa)
DYRK3Dual specificity tyrosine phosphorylation regulated kinase 3. (583 aa)
DYRK1ADual specificity tyrosine phosphorylation regulated kinase 1A. (758 aa)
PRKACAProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (294 aa)
PKN1Protein kinase domain-containing protein. (839 aa)
MAPK10Mitogen-activated protein kinase. (550 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (478 aa)
OXSR1Oxidative stress responsive kinase 1. (530 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (341 aa)
UMODUromodulin. (676 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
DCAF1DDB1 and CUL4 associated factor 1. (1507 aa)
HIPK1Homeodomain interacting protein kinase 1. (1142 aa)
CLK1CDC like kinase 1; Belongs to the protein kinase superfamily. (457 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2578 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
ENSNLEP00000036861Uncharacterized protein. (119 aa)
CITCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2048 aa)
CDC42BPBCDC42 binding protein kinase beta; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1699 aa)
CDK10Cyclin dependent kinase 10; Belongs to the protein kinase superfamily. (358 aa)
TNKSPoly [ADP-ribose] polymerase. (1312 aa)
HIPK2Homeodomain interacting protein kinase 2. (1198 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (533 aa)
CHEK1Checkpoint kinase 1. (492 aa)
LOC100593010Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (459 aa)
LMTK2Lemur tyrosine kinase 2. (1501 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (498 aa)
CAMK2AProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (476 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1359 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
WNK1WNK lysine deficient protein kinase 1. (2833 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
CDC42BPANon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1737 aa)
MARK2Non-specific serine/threonine protein kinase. (788 aa)
DYRK2Dual specificity tyrosine phosphorylation regulated kinase 2. (604 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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