STRINGSTRING
PAWR PAWR ITGA2 ITGA2 P2RX4 P2RX4 ENSNLEP00000044067 ENSNLEP00000044067 PROK2 PROK2 OPRM1 OPRM1 NR2F6 NR2F6 SCN10A SCN10A NTRK1 NTRK1 TAC4 TAC4 RETREG1-2 RETREG1-2 AQP1 AQP1 KCNA1 KCNA1 BDKRB1 BDKRB1 PTGS2 PTGS2 TRPV1 TRPV1 EDNRB EDNRB P2RX7 P2RX7 LOC100581245 LOC100581245 POMK POMK PRDM12 PRDM12 RETREG1 RETREG1 TRPA1 TRPA1 CHRNB2 CHRNB2 OPRL1 OPRL1 MMP24 MMP24 NTSR1 NTSR1 NLGN2 NLGN2 CNR2 CNR2 TMEM120A TMEM120A NPY1R NPY1R HOXD1 HOXD1 IAPP IAPP PHF24 PHF24 IL12B IL12B CDK5 CDK5 ASIC3 ASIC3 EPHB1 EPHB1 MME MME KCNA2 KCNA2 SCN9A SCN9A SCN1A SCN1A NIPSNAP1 NIPSNAP1 GIP GIP MAPK3 MAPK3 G1QLB3_NOMLE G1QLB3_NOMLE CALCA CALCA PENK PENK EDN1 EDN1 ANO1 ANO1 GRIN2A GRIN2A FYN FYN BACE1 BACE1 HTR2A HTR2A SCN3B SCN3B CXCL12 CXCL12 OPRK1 OPRK1 IL18 IL18 ENSNLEP00000036861 ENSNLEP00000036861 MECP2 MECP2 ENSNLEP00000035827 ENSNLEP00000035827 KCND2 KCND2 LXN LXN PTGES PTGES GRM1 GRM1 TAC1 TAC1 TACR1 TACR1 P2RY1 P2RY1 UCHL1 UCHL1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PAWRPro-apoptotic WT1 regulator. (340 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1181 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (404 aa)
ENSNLEP00000044067Uncharacterized protein. (108 aa)
PROK2Prokineticin 2. (129 aa)
OPRM1Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. (475 aa)
NR2F6Nuclear receptor subfamily 2 group F member 6. (358 aa)
SCN10ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1959 aa)
NTRK1Tyrosine-protein kinase receptor. (787 aa)
TAC4Uncharacterized protein. (86 aa)
RETREG1-2Reticulophagy regulator 1 isoform X2. (141 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (269 aa)
KCNA1Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family. (495 aa)
BDKRB1G_PROTEIN_RECEP_F1_2 domain-containing protein. (284 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (850 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (532 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
LOC100581245G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the tubulin family. (768 aa)
POMKProtein O-mannose kinase. (350 aa)
PRDM12SET domain-containing protein. (227 aa)
RETREG1Reticulophagy regulator 1. (455 aa)
TRPA1Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1094 aa)
CHRNB2Uncharacterized protein. (329 aa)
OPRL1Opioid related nociceptin receptor 1; Belongs to the G-protein coupled receptor 1 family. (323 aa)
MMP24Matrix metallopeptidase 24. (563 aa)
NTSR1Neurotensin receptor 1; Belongs to the G-protein coupled receptor 1 family. (394 aa)
NLGN2Neuroligin 2. (768 aa)
CNR2Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. (360 aa)
TMEM120ATransmembrane protein 120A. (365 aa)
NPY1RNeuropeptide Y receptor Y1; Belongs to the G-protein coupled receptor 1 family. (383 aa)
HOXD1Homeobox D1. (328 aa)
IAPPIslet amyloid polypeptide. (89 aa)
PHF24Zf_RING domain-containing protein. (244 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (328 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (320 aa)
ASIC3Acid sensing ion channel subunit 3; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (507 aa)
EPHB1EPH receptor B1. (984 aa)
MMEMembrane metalloendopeptidase. (750 aa)
KCNA2BTB domain-containing protein; Belongs to the potassium channel family. (356 aa)
SCN9ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1993 aa)
SCN1ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2009 aa)
NIPSNAP1Nipsnap homolog 1. (256 aa)
GIPGastric inhibitory polypeptide. (153 aa)
MAPK3Mitogen-activated protein kinase. (278 aa)
G1QLB3_NOMLEC-C motif chemokine. (138 aa)
CALCACalcitonin related polypeptide alpha. (141 aa)
PENKProenkephalin. (267 aa)
EDN1Endothelin 1. (211 aa)
ANO1Anoctamin. (912 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1464 aa)
FYNTyrosine-protein kinase. (537 aa)
BACE1Beta-secretase 1; Belongs to the peptidase A1 family. (501 aa)
HTR2A5-hydroxytryptamine receptor 2A. (471 aa)
SCN3BSodium voltage-gated channel beta subunit 3. (215 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (140 aa)
OPRK1Opioid receptor kappa 1; Belongs to the G-protein coupled receptor 1 family. (380 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
ENSNLEP00000036861Uncharacterized protein. (119 aa)
MECP2MBD domain-containing protein. (156 aa)
ENSNLEP00000035827G_PROTEIN_RECEP_F1_2 domain-containing protein. (308 aa)
KCND2Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (630 aa)
LXNLatexin. (222 aa)
PTGESProstaglandin E synthase. (163 aa)
GRM1Glutamate metabotropic receptor 1. (1195 aa)
TAC1Tachykinin precursor 1. (129 aa)
TACR1Tachykinin receptor 1. (406 aa)
P2RY1Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
UCHL1Ubiquitin carboxyl-terminal hydrolase. (223 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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