STRINGSTRING
EPHB3 EPHB3 RAPGEF2 RAPGEF2 B4GALT6 B4GALT6 MAP2 MAP2 TTC36 TTC36 SECISBP2 SECISBP2 DRAXIN DRAXIN ZMIZ1 ZMIZ1 GBX2 GBX2 G1RJA2_NOMLE G1RJA2_NOMLE CHRNB2 CHRNB2 DCC DCC PTEN PTEN NIN NIN LEP LEP UQCRQ UQCRQ PLXNA4 PLXNA4 NR2E1 NR2E1 LRRC45 LRRC45 SPTBN4 SPTBN4 GATA2 GATA2 DCX DCX NPY NPY FGFR2 FGFR2 GABRB1 GABRB1 SZT2 SZT2 NRP1 NRP1 BTG2 BTG2 SOX1 SOX1 MYCBP2 MYCBP2 HSP90AB1 HSP90AB1 SEMA3E SEMA3E ASCL1 ASCL1 PHOX2B PHOX2B DRD2 DRD2 DCLK1 DCLK1 FEZF2 FEZF2 LINGO1 LINGO1 LHX8 LHX8 NFIB NFIB SPG11 SPG11 CNTN2 CNTN2 ENSNLEP00000036861 ENSNLEP00000036861 CDH11 CDH11 AGBL4 AGBL4 DRD1 DRD1 NDNF NDNF ENSNLEP00000040092 ENSNLEP00000040092 PLXNA3 PLXNA3 NHLH2 NHLH2 B4GALT5 B4GALT5 EPHB2 EPHB2 EPHA4 EPHA4 NRP2 NRP2 ENSNLEP00000043017 ENSNLEP00000043017 GBA2 GBA2 RAC3 RAC3 SLC4A10 SLC4A10 LHX6 LHX6 TAOK1 TAOK1 TSKU TSKU KIFBP KIFBP SLIT2 SLIT2 ADARB1 ADARB1 MPP5 MPP5 NR4A2 NR4A2 GLI2 GLI2 PLXNA1 PLXNA1 ATP7A ATP7A FBXO45 FBXO45 HPRT1 HPRT1 DISC1 DISC1 NOVA2 NOVA2 EPHB6 EPHB6 ARHGAP35 ARHGAP35 TCTN1 TCTN1 NTRK2 NTRK2 AGTPBP1 AGTPBP1 EPHB1 EPHB1 OGDH OGDH CDK5 CDK5 DCLK2 DCLK2 SCYL2 SCYL2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EPHB3EPH receptor B3. (1053 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1642 aa)
B4GALT6Beta-1,4-galactosyltransferase 6. (382 aa)
MAP2Microtubule-associated protein. (1827 aa)
TTC36Tetratricopeptide repeat domain 36. (191 aa)
SECISBP2SECIS binding protein 2. (787 aa)
DRAXINDraxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. (349 aa)
ZMIZ1Zinc finger MIZ-type containing 1. (1067 aa)
GBX2Gastrulation brain homeobox 2. (348 aa)
G1RJA2_NOMLEIGv domain-containing protein. (221 aa)
CHRNB2Uncharacterized protein. (329 aa)
DCCDCC netrin 1 receptor. (1322 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
NINNinein. (2133 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
UQCRQUbiquinol-cytochrome c reductase complex III subunit VII. (82 aa)
PLXNA4Plexin A4. (1864 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (422 aa)
LRRC45Leucine rich repeat containing 45. (665 aa)
SPTBN4Spectrin beta chain; Belongs to the spectrin family. (2474 aa)
GATA2GATA binding protein 2. (480 aa)
DCXDoublecortin. (408 aa)
NPYNeuropeptide Y. (97 aa)
FGFR2Fibroblast growth factor receptor. (820 aa)
GABRB1Gamma-aminobutyric acid type A receptor beta1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (474 aa)
SZT2SZT2 subunit of KICSTOR complex. (3454 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (901 aa)
BTG2BTG anti-proliferation factor 2. (158 aa)
SOX1HMG box domain-containing protein. (251 aa)
MYCBP2MYC binding protein 2. (4726 aa)
HSP90AB1Heat shock protein 90 alpha family class B member 1. (665 aa)
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (775 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (235 aa)
PHOX2BPaired like homeobox 2B. (314 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (445 aa)
DCLK1Doublecortin like kinase 1. (740 aa)
FEZF2FEZ family zinc finger 2. (446 aa)
LINGO1Leucine rich repeat and Ig domain containing 1. (619 aa)
LHX8LIM homeobox 8. (377 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (487 aa)
SPG11SPG11 vesicle trafficking associated, spatacsin. (2443 aa)
CNTN2Contactin 2. (1049 aa)
ENSNLEP00000036861Uncharacterized protein. (119 aa)
CDH11Cadherin 11; Cadherins are calcium-dependent cell adhesion proteins. (796 aa)
AGBL4ATP/GTP binding protein like 4. (503 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
NDNFNeuron derived neurotrophic factor. (568 aa)
ENSNLEP00000040092Protein kinase domain-containing protein. (281 aa)
PLXNA3Plexin A3. (1828 aa)
NHLH2Nescient helix-loop-helix 2. (135 aa)
B4GALT5Beta-1,4-galactosyltransferase 5. (388 aa)
EPHB2EPH receptor B2. (1015 aa)
EPHA4EPH receptor A4. (967 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (930 aa)
ENSNLEP00000043017HATPase_c domain-containing protein. (648 aa)
GBA2Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide. (907 aa)
RAC3Rac family small GTPase 3. (205 aa)
SLC4A10Anion exchange protein. (1140 aa)
LHX6LIM homeobox 6. (352 aa)
TAOK1TAO kinase 1. (1002 aa)
TSKUTsukushi, small leucine rich proteoglycan. (354 aa)
KIFBPKIF1 binding protein. (646 aa)
SLIT2Slit guidance ligand 2. (1389 aa)
ADARB1Adenosine deaminase RNA specific B1. (741 aa)
MPP5Membrane palmitoylated protein 5; Belongs to the MAGUK family. (675 aa)
NR4A2Nuclear receptor subfamily 4 group A member 2. (598 aa)
GLI2GLI family zinc finger 2. (1589 aa)
PLXNA1Plexin A1. (1880 aa)
ATP7AATPase copper transporting alpha. (1460 aa)
FBXO45F-box protein 45. (288 aa)
HPRT1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (218 aa)
DISC1Uncharacterized protein. (202 aa)
NOVA2Uncharacterized protein. (274 aa)
EPHB6EPH receptor B6. (1019 aa)
ARHGAP35Rho GTPase activating protein 35. (1499 aa)
TCTN1Tectonic family member 1. (598 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
AGTPBP1ATP/GTP binding protein 1. (1236 aa)
EPHB1EPH receptor B1. (984 aa)
OGDHOxoglutarate dehydrogenase. (1038 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (320 aa)
DCLK2Doublecortin like kinase 2. (783 aa)
SCYL2SCY1 like pseudokinase 2. (933 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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