STRINGSTRING
RAB27A RAB27A SLC24A5 SLC24A5 MREG MREG SOX10 SOX10 LRMDA LRMDA OCA2 OCA2 ADAMTS20 ADAMTS20 MEF2C MEF2C BCL2 BCL2 EDN3 EDN3 BLOC1S6 BLOC1S6 USP13 USP13 GLI3 GLI3 CITED1 CITED1 HPS6 HPS6 TYRP1 TYRP1 EDNRB EDNRB MITF MITF ENPP1 ENPP1 ADAMTS9 ADAMTS9 KIT KIT HPS4 HPS4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RAB27ARAB27A, member RAS oncogene family. (221 aa)
SLC24A5Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (500 aa)
MREGMelanoregulin. (214 aa)
SOX10HMG box domain-containing protein. (236 aa)
LRMDALeucine rich melanocyte differentiation associated. (226 aa)
OCA2OCA2 melanosomal transmembrane protein. (832 aa)
ADAMTS20ADAM metallopeptidase with thrombospondin type 1 motif 20. (1912 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
EDN3Uncharacterized protein. (211 aa)
BLOC1S6Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...] (176 aa)
USP13Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (807 aa)
GLI3GLI family zinc finger 3. (1502 aa)
CITED1Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (219 aa)
HPS6Hermansky-Pudlak syndrome 6 protein homolog; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. (775 aa)
TYRP1Tyrosinase related protein 1. (537 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (532 aa)
MITFMelanocyte inducing transcription factor. (526 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase 1. (827 aa)
ADAMTS9ADAM metallopeptidase with thrombospondin type 1 motif 9. (1935 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (969 aa)
HPS4HPS4 biogenesis of lysosomal organelles complex 3 subunit 2. (708 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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