STRINGSTRING
CPTP CPTP MEFV MEFV CTNNBIP1 CTNNBIP1 VIL1 VIL1 KANK1 KANK1 ULK1 ULK1 CLDN7 CLDN7 CAPZB CAPZB TFIP11 TFIP11 RDX RDX PRKCD PRKCD MAP2 MAP2 TWF2 TWF2 IMPACT IMPACT TMOD3 TMOD3 TMOD2 TMOD2 SSH3 SSH3 MYADM MYADM SOST SOST FAM49B FAM49B ZNF827 ZNF827 RPL13A RPL13A VILL VILL TREM2 TREM2 IAPP IAPP MAPRE1 MAPRE1 OPRD1 OPRD1 G1RGJ3_NOMLE G1RGJ3_NOMLE G1RHS2_NOMLE G1RHS2_NOMLE TMEM130 TMEM130 ISL1 ISL1 ARFGEF1 ARFGEF1 TRAF3IP1 TRAF3IP1 CAPZA2 CAPZA2 CLIP3 CLIP3 LCMT1 LCMT1 DKK1 DKK1 LMOD2 LMOD2 SPTA1 SPTA1 DACT1 DACT1 AIDA AIDA PPM1A PPM1A FLII FLII SPTBN4 SPTBN4 BBS4 BBS4 SPTB SPTB SNCA SNCA MKKS MKKS KANK4 KANK4 ADD3 ADD3 VPS35 VPS35 LOC100581245 LOC100581245 SCIN SCIN PTGER4 PTGER4 CLU CLU AVIL AVIL HSPA5 HSPA5 TWF1 TWF1 KIF14 KIF14 LMOD1 LMOD1 CAPZA3 CAPZA3 TMOD1 TMOD1 LMO4 LMO4 LDLRAD4 LDLRAD4 HDAC6 HDAC6 DYRK1A DYRK1A SVIL SVIL TMSB15A TMSB15A GSK3B GSK3B ENSNLEP00000026534 ENSNLEP00000026534 PRRT2 PRRT2 ENSNLEP00000027025 ENSNLEP00000027025 SOX9 SOX9 DDX3X DDX3X SORL1 SORL1 ENSNLEP00000029188 ENSNLEP00000029188 ADD1 ADD1 NCK2 NCK2 CRYAB CRYAB DNAJC15 DNAJC15 ADD2 ADD2 ENSNLEP00000031566 ENSNLEP00000031566 JAM3 JAM3 ENSNLEP00000032357 ENSNLEP00000032357 ENSNLEP00000032709 ENSNLEP00000032709 LOC100601030 LOC100601030 SSH1 SSH1 LAMP2 LAMP2 ENSNLEP00000034296 ENSNLEP00000034296 SPTBN5 SPTBN5 CAPZA1 CAPZA1 SSH2 SSH2 ENSNLEP00000035044 ENSNLEP00000035044 EP300 EP300 ENSNLEP00000035981 ENSNLEP00000035981 ENSNLEP00000036158 ENSNLEP00000036158 LOC100593615 LOC100593615 FHOD3 FHOD3 DMTN DMTN AKAIN1 AKAIN1 NLRC3 NLRC3 BIRC2 BIRC2 ENSNLEP00000038312 ENSNLEP00000038312 SVIP SVIP STMN2 STMN2 LOC100606191 LOC100606191 HSF1 HSF1 VDAC2 VDAC2 SPTBN1 SPTBN1 ENSNLEP00000039612 ENSNLEP00000039612 CLUL1 CLUL1 ARHGEF7 ARHGEF7 SPTBN2 SPTBN2 PEX5 PEX5 GSN GSN CDC42 CDC42 SPTAN1 SPTAN1 BCL11A BCL11A TBCD TBCD ANKRD27 ANKRD27 PARK7 PARK7 PMEPA1 PMEPA1 TUBB4A TUBB4A ENSNLEP00000045854 ENSNLEP00000045854 ENSNLEP00000045860 ENSNLEP00000045860 PFN1-2 PFN1-2 STMN1 STMN1 SLIT2 SLIT2 SRC SRC ENSNLEP00000048831 ENSNLEP00000048831 SMAD6 SMAD6 ENSNLEP00000049000 ENSNLEP00000049000 INPP5J INPP5J EPS8 EPS8 NCK1 NCK1 CDH5 CDH5 NOP53 NOP53 FKBP4 FKBP4 EML2 EML2 LMOD3 LMOD3 CAPG CAPG TBX20 TBX20 KANK3 KANK3 PFN4 PFN4 PRKCZ PRKCZ TMC8 TMC8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CPTPCeramide-1-phosphate transfer protein. (214 aa)
MEFVMEFV innate immuity regulator, pyrin. (781 aa)
CTNNBIP1Catenin beta interacting protein 1. (81 aa)
VIL1Villin 1. (827 aa)
KANK1KN motif and ankyrin repeat domains 1. (1352 aa)
ULK1Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. (1049 aa)
CLDN7Uncharacterized protein. (147 aa)
CAPZBF-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (262 aa)
TFIP11Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...] (830 aa)
RDXRadixin. (604 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
MAP2Microtubule-associated protein. (1827 aa)
TWF2Twinfilin actin binding protein 2. (349 aa)
IMPACTImpact RWD domain protein. (320 aa)
TMOD3Tropomodulin 3. (352 aa)
TMOD2Tropomodulin 2. (351 aa)
SSH3Slingshot protein phosphatase 3. (612 aa)
MYADMMyeloid associated differentiation marker. (322 aa)
SOSTSclerostin. (213 aa)
FAM49BFamily with sequence similarity 49 member B. (324 aa)
ZNF827Zinc finger protein 827. (1081 aa)
RPL13AUncharacterized protein; Belongs to the universal ribosomal protein uL13 family. (195 aa)
VILLVillin like. (860 aa)
TREM2Ig-like domain-containing protein. (222 aa)
IAPPIslet amyloid polypeptide. (89 aa)
MAPRE1Microtubule associated protein RP/EB family member 1. (268 aa)
OPRD1G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (265 aa)
G1RGJ3_NOMLEUncharacterized protein. (283 aa)
G1RHS2_NOMLEHP domain-containing protein. (80 aa)
TMEM130Transmembrane protein 130. (406 aa)
ISL1ISL LIM homeobox 1. (349 aa)
ARFGEF1ADP ribosylation factor guanine nucleotide exchange factor 1. (1849 aa)
TRAF3IP1TRAF3 interacting protein 1. (691 aa)
CAPZA2F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (232 aa)
CLIP3CAP-Gly domain containing linker protein 3. (504 aa)
LCMT1Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. (340 aa)
DKK1Dickkopf-like protein 1. (266 aa)
LMOD2Leiomodin 2. (550 aa)
SPTA1Spectrin alpha, erythrocytic 1. (2387 aa)
DACT1Dishevelled binding antagonist of beta catenin 1. (837 aa)
AIDAAxin interactor, dorsalization associated. (306 aa)
PPM1AProtein phosphatase, Mg2+/Mn2+ dependent 1A. (455 aa)
FLIIFLII actin remodeling protein. (1161 aa)
SPTBN4Spectrin beta chain; Belongs to the spectrin family. (2474 aa)
BBS4Bardet-Biedl syndrome 4. (518 aa)
SPTBSpectrin beta chain; Belongs to the spectrin family. (2266 aa)
SNCAAlpha-synuclein; Belongs to the synuclein family. (140 aa)
MKKSMcKusick-Kaufman syndrome. (570 aa)
KANK4KN motif and ankyrin repeat domains 4. (995 aa)
ADD3Adducin 3. (672 aa)
VPS35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (790 aa)
LOC100581245G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the tubulin family. (768 aa)
SCINScinderin. (715 aa)
PTGER4Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (490 aa)
CLUClusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. (448 aa)
AVILAdvillin. (819 aa)
HSPA5Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)
TWF1Twinfilin actin binding protein 1. (384 aa)
KIF14Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1648 aa)
LMOD1Leiomodin 1. (621 aa)
CAPZA3F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (299 aa)
TMOD1Tropomodulin 1. (365 aa)
LMO4LIM domain only 4. (165 aa)
LDLRAD4Low density lipoprotein receptor class A domain containing 4. (306 aa)
HDAC6Uncharacterized protein. (146 aa)
DYRK1ADual specificity tyrosine phosphorylation regulated kinase 1A. (758 aa)
SVILSupervillin. (1949 aa)
TMSB15AThymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (45 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (478 aa)
ENSNLEP00000026534Uncharacterized protein. (139 aa)
PRRT2Proline rich transmembrane protein 2. (349 aa)
ENSNLEP00000027025PPM-type phosphatase domain-containing protein. (340 aa)
SOX9SRY-box transcription factor 9. (510 aa)
DDX3XDEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (704 aa)
SORL1Sortilin related receptor 1. (2174 aa)
ENSNLEP00000029188Uncharacterized protein. (60 aa)
ADD1Adducin 1. (753 aa)
NCK2Cytoplasmic protein. (380 aa)
CRYABCrystallin alpha B; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (175 aa)
DNAJC15DnaJ heat shock protein family (Hsp40) member C15. (150 aa)
ADD2Adducin 2. (726 aa)
ENSNLEP00000031566HP domain-containing protein. (71 aa)
JAM3Junctional adhesion molecule 3. (275 aa)
ENSNLEP00000032357Uncharacterized protein; Belongs to the universal ribosomal protein uL13 family. (197 aa)
ENSNLEP00000032709Profilin; Belongs to the profilin family. (120 aa)
LOC100601030Uncharacterized protein. (79 aa)
SSH1Slingshot protein phosphatase 1. (1032 aa)
LAMP2Lysosomal associated membrane protein 2. (411 aa)
ENSNLEP00000034296DJ-1_PfpI domain-containing protein. (133 aa)
SPTBN5Spectrin beta, non-erythrocytic 5. (3637 aa)
CAPZA1F-actin-capping protein subunit alpha-2; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity). (286 aa)
SSH2Slingshot protein phosphatase 2. (1450 aa)
ENSNLEP00000035044Uncharacterized protein. (195 aa)
EP300E1A binding protein p300. (2306 aa)
ENSNLEP00000035981Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (393 aa)
ENSNLEP00000036158Uncharacterized protein; Belongs to the universal ribosomal protein uL13 family. (201 aa)
LOC100593615TPR_REGION domain-containing protein. (160 aa)
FHOD3Formin homology 2 domain containing 3. (1567 aa)
DMTNDematin actin binding protein. (406 aa)
AKAIN1A-kinase anchor inhibitor 1. (69 aa)
NLRC3NLR family CARD domain containing 3. (1102 aa)
BIRC2Baculoviral IAP repeat containing 2. (615 aa)
ENSNLEP00000038312Uncharacterized protein; Belongs to the heat shock protein 70 family. (615 aa)
SVIPSmall VCP interacting protein. (77 aa)
STMN2Stathmin; Belongs to the stathmin family. (185 aa)
LOC100606191Uncharacterized protein. (159 aa)
HSF1HSF_DOMAIN domain-containing protein. (272 aa)
VDAC2Voltage dependent anion channel 2. (297 aa)
SPTBN1Spectrin beta chain; Belongs to the spectrin family. (2289 aa)
ENSNLEP00000039612Uncharacterized protein. (517 aa)
CLUL1Clusterin; Belongs to the clusterin family. (518 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (747 aa)
SPTBN2Spectrin beta chain; Belongs to the spectrin family. (2353 aa)
PEX5Peroxisomal biogenesis factor 5. (637 aa)
GSNGelsolin. (814 aa)
CDC42Cell division cycle 42. (191 aa)
SPTAN1Spectrin alpha, non-erythrocytic 1. (2410 aa)
BCL11ABAF chromatin remodeling complex subunit BCL11A. (838 aa)
TBCDTubulin folding cofactor D. (1208 aa)
ANKRD27Ankyrin repeat domain 27. (1050 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
PMEPA1Prostate transmembrane protein, androgen induced 1. (274 aa)
TUBB4ATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (372 aa)
ENSNLEP00000045854Uncharacterized protein. (185 aa)
ENSNLEP00000045860Uncharacterized protein. (64 aa)
PFN1-2Profilin; Belongs to the profilin family. (128 aa)
STMN1Stathmin; Belongs to the stathmin family. (172 aa)
SLIT2Slit guidance ligand 2. (1389 aa)
SRCTyrosine-protein kinase. (537 aa)
ENSNLEP00000048831F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (255 aa)
SMAD6Mothers against decapentaplegic homolog. (465 aa)
ENSNLEP00000049000Uncharacterized protein. (110 aa)
INPP5JInositol polyphosphate-5-phosphatase J. (1007 aa)
EPS8Epidermal growth factor receptor pathway substrate 8. (822 aa)
NCK1Cytoplasmic protein. (377 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (687 aa)
NOP53Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (478 aa)
FKBP4Peptidylprolyl isomerase. (424 aa)
EML2EMAP like 2. (722 aa)
LMOD3Leiomodin 3. (559 aa)
CAPGCapping actin protein, gelsolin like. (348 aa)
TBX20T-box transcription factor 20. (447 aa)
KANK3KN motif and ankyrin repeat domains 3. (840 aa)
PFN4Profilin; Belongs to the profilin family. (128 aa)
PRKCZProtein kinase C zeta. (507 aa)
TMC8Transmembrane channel-like protein. (698 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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