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| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | MNAT1 | CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa) |
| | CAB39 | Calcium binding protein 39. (341 aa) |
| | BMP2 | Bone morphogenetic protein 2. (396 aa) |
| | BMPR1B | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | CCL5 | C-C motif chemokine. (91 aa) |
| | MTCP1 | Mature T cell proliferation 1. (107 aa) |
| | MADD | MAP kinase activating death domain. (1459 aa) |
| | CARD10 | Caspase recruitment domain family member 10. (898 aa) |
| | DBF4 | DBF4 zinc finger. (674 aa) |
| | PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (233 aa) |
| | ALK | Uncharacterized protein. (1134 aa) |
| | RIPK3 | Receptor interacting serine/threonine kinase 3. (506 aa) |
| | NCKAP1L | NCK associated protein 1 like. (1109 aa) |
| | ENSNLEP00000034296 | DJ-1_PfpI domain-containing protein. (133 aa) |
| | CCNY | Cyclin Y; Belongs to the cyclin family. (363 aa) |
| | ENSNLEP00000035153 | Prohibitin. (261 aa) |
| | TLR6 | TIR domain-containing protein. (472 aa) |
| | ENSNLEP00000035385 | Prohibitin. (283 aa) |
| | ENSNLEP00000035670 | CYCLIN domain-containing protein; Belongs to the cyclin family. (335 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1206 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | ALKAL2 | ALK and LTK ligand 2. (152 aa) |
| | MLST8 | MTOR associated protein, LST8 homolog. (326 aa) |
| | PRLR | Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (622 aa) |
| | ENSNLEP00000037203 | Prohibitin. (260 aa) |
| | ADRA2B | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (391 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) |
| | CKS2 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa) |
| | ADCY8 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1255 aa) |
| | BORA | BORA aurora kinase A activator. (634 aa) |
| | ENSNLEP00000039390 | Protein kinase domain-containing protein. (673 aa) |
| | ENSNLEP00000039490 | Uncharacterized protein. (50 aa) |
| | PDGFC | Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa) |
| | AREG | EGF-like domain-containing protein. (274 aa) |
| | LOC100593010 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (459 aa) |
| | ENSNLEP00000040637 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (166 aa) |
| | ENSNLEP00000040950 | Uncharacterized protein; Belongs to the eukaryotic ribosomal protein P1/P2 family. (114 aa) |
| | ANGPT1 | Angiopoietin 1. (498 aa) |
| | ENSNLEP00000041273 | Uncharacterized protein. (190 aa) |
| | CAMKK2 | Calcium/calmodulin dependent protein kinase kinase 2. (591 aa) |
| | TPX2 | TPX2 microtubule nucleation factor. (783 aa) |
| | ENSNLEP00000042144 | Prohibitin. (291 aa) |
| | EMP2 | Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa) |
| | ABI1 | Abl interactor 1. (508 aa) |
| | TAOK2 | TAO kinase 2. (1246 aa) |
| | TRAF4 | TNF receptor-associated factor. (471 aa) |
| | ENSNLEP00000042917 | Prohibitin. (131 aa) |
| | ENSNLEP00000042936 | Protein kinase domain-containing protein. (201 aa) |
| | PARK7 | Parkinsonism associated deglycase. (189 aa) |
| | TIRAP | TIR domain containing adaptor protein. (221 aa) |
| | ENSNLEP00000043969 | CSN8_PSD8_EIF3K domain-containing protein. (192 aa) |
| | DAB2IP | DAB2 interacting protein. (1159 aa) |
| | CD40LG | CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa) |
| | GPRC5B | G protein-coupled receptor class C group 5 member B. (344 aa) |
| | SLC1A1 | Amino acid transporter. (457 aa) |
| | IGF1 | IlGF domain-containing protein. (196 aa) |
| | WNK1 | WNK lysine deficient protein kinase 1. (2833 aa) |
| | NRG1 | Neuregulin 1. (713 aa) |
| | TAOK1 | TAO kinase 1. (1002 aa) |
| | CCDC88A | Coiled-coil domain containing 88A. (1871 aa) |
| | ENSNLEP00000046123 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (136 aa) |
| | HNF1A | Uncharacterized protein. (562 aa) |
| | ENSNLEP00000046375 | Prohibitin. (169 aa) |
| | FBN1 | Fibrillin 1. (2873 aa) |
| | GHR | Growth hormone receptor. (645 aa) |
| | ITGB1BP1 | Integrin subunit beta 1 binding protein 1. (200 aa) |
| | ERBB3 | Erb-b2 receptor tyrosine kinase 3. (1343 aa) |
| | INCENP | Inner centromere protein. (920 aa) |
| | EPGN | Epithelial mitogen. (154 aa) |
| | LOC100580239 | Uncharacterized protein; Belongs to the eukaryotic ribosomal protein P1/P2 family. (114 aa) |
| | MARK2 | Non-specific serine/threonine protein kinase. (788 aa) |
| | SRC | Tyrosine-protein kinase. (537 aa) |
| | AXIN1 | Axin 1. (837 aa) |
| | CARD14 | Caspase recruitment domain family member 14. (931 aa) |
| | ERCC6 | ERCC excision repair 6, chromatin remodeling factor. (1492 aa) |
| | G1S167_NOMLE | Uncharacterized protein. (410 aa) |
| | TNFRSF10A | TNF receptor superfamily member 10a. (471 aa) |
| | P2RX7 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa) |
| | EFNA5 | Ephrin A5; Belongs to the ephrin family. (228 aa) |
| | PIM1 | Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (402 aa) |
| | CLSPN | Claspin. (1315 aa) |
| | COPS8 | COP9 signalosome subunit 8. (209 aa) |
| | BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa) |
| | PRKCZ | Protein kinase C zeta. (507 aa) |
| | CD86 | CD86 molecule. (329 aa) |
| | INSR | Insulin receptor. (1232 aa) |
| | TCL1B | Uncharacterized protein. (123 aa) |
| | TCL1A | T cell leukemia/lymphoma 1A. (114 aa) |
| | ALKAL1 | ALK and LTK ligand 1. (129 aa) |
| | CCNK | Cyclin K; Belongs to the cyclin family. (545 aa) |
| | DGKQ | Diacylglycerol kinase. (673 aa) |
| | RGCC | Regulator of cell cycle. (137 aa) |
| | CALCA | Calcitonin related polypeptide alpha. (141 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (423 aa) |
| | PAK2 | Non-specific serine/threonine protein kinase. (524 aa) |
| | MOB3A | MOB kinase activator 3A. (217 aa) |
| | FAM20A | Fam20C domain-containing protein. (248 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) |
| | PHB | Prohibitin. (272 aa) |
| | MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (383 aa) |
| | UCN | Urocortin. (124 aa) |
| | NTF3 | Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (268 aa) |
| | CAB39L | Calcium binding protein 39 like. (337 aa) |
| | PPP2R3C | Protein phosphatase 2 regulatory subunit B''gamma. (453 aa) |
| | GPRC5A | G protein-coupled receptor class C group 5 member A. (357 aa) |
| | GPRC5D | G protein-coupled receptor class C group 5 member D. (343 aa) |
| | LTK | Leukocyte receptor tyrosine kinase. (864 aa) |
| | PPIA | Peptidyl-prolyl cis-trans isomerase A, N-terminally processed; PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding; Belongs to the cyclophilin-type PPIase family. PPIase A subfamily. (165 aa) |
| | CCNB1 | Cyclin B1; Belongs to the cyclin family. (429 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) |
| | GHRL | Ghrelin and obestatin prepropeptide. (117 aa) |
| | MOB3B | MOB kinase activator 3B. (216 aa) |
| | PHB2 | Prohibitin. (299 aa) |
| | DBF4B | DBF4-type domain-containing protein. (407 aa) |
| | ACVR2B | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (512 aa) |
| | ECT2 | Epithelial cell transforming 2. (914 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa) |
| | MAP3K13 | Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (966 aa) |
| | STRADB | STE20 related adaptor beta. (412 aa) |
| | ALS2 | Alsin Rho guanine nucleotide exchange factor ALS2. (1628 aa) |
| | CCNYL1 | Cyclin Y like 1; Belongs to the cyclin family. (289 aa) |
| | ERBB4 | Receptor protein-tyrosine kinase. (1308 aa) |
| | PRKCD | Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) |
| | MOB1B | MOB kinase activator 1B. (221 aa) |
| | EREG | Epiregulin. (169 aa) |
| | BTC | Betacellulin. (178 aa) |
| | DYNAP | Dynactin associated protein. (210 aa) |
| | TOM1L1 | Target of myb1 like 1 membrane trafficking protein; Belongs to the TOM1 family. (476 aa) |
| | MALT1 | MALT1 paracaspase. (824 aa) |
| | SLC11A1 | Solute carrier family 11 member 1. (550 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa) |
| | CHRNA3 | Cholinergic receptor nicotinic alpha 3 subunit. (503 aa) |
| | JAK2 | Tyrosine-protein kinase. (1132 aa) |
| | STAP1 | Signal transducing adaptor family member 1. (295 aa) |
| | HBEGF | Heparin binding EGF like growth factor. (208 aa) |
| | ANGPT4 | Angiopoietin 4. (480 aa) |
| | LOC100592336 | PH_3 domain-containing protein. (247 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | ETAA1 | ETAA1 activator of ATR kinase. (897 aa) |
| | TGFA | Transforming growth factor alpha. (166 aa) |
| | GAS6 | Growth arrest specific 6. (679 aa) |
| | GREM1 | CTCK domain-containing protein. (143 aa) |
| | PIBF1 | Progesterone immunomodulatory binding factor 1. (758 aa) |
| | AFAP1L2 | Actin filament associated protein 1 like 2. (801 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (871 aa) |
| | RICTOR | RPTOR independent companion of MTOR complex 2. (1709 aa) |
| | MOB3C | MOB kinase activator 3C. (216 aa) |
| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1208 aa) |
| | WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa) |
| | AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2. (1186 aa) |
| | MAP3K12 | Mitogen-activated protein kinase kinase kinase 12. (747 aa) |
| | CCNT1 | Cyclin T1; Belongs to the cyclin family. (726 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa) |
| | KIF14 | Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1648 aa) |
| | CHI3L1 | Chitinase 3 like 1; Belongs to the glycosyl hydrolase 18 family. (403 aa) |
| | ADRA2C | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (374 aa) |
| | CDK5R2 | Cyclin-dependent kinase 5 activator. (367 aa) |
| | G1SB75_NOMLE | Uncharacterized protein. (81 aa) |
| | ADNP | Activity dependent neuroprotector homeobox. (1102 aa) |
| | PINK1 | Protein kinase domain-containing protein. (563 aa) |
| | PRNP | Major prion protein; Belongs to the prion family. (253 aa) |
| | BMPR1A | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (533 aa) |
| | ENSNLEP00000025459 | Uncharacterized protein; Belongs to the eukaryotic ribosomal protein P1/P2 family. (103 aa) |
| | ENSNLEP00000025813 | Prohibitin. (188 aa) |
| | GPRC5C | G protein-coupled receptor class C group 5 member C. (440 aa) |
| | STK3 | Serine/threonine kinase 3. (519 aa) |
| | DAZAP2 | Uncharacterized protein. (168 aa) |
| | MOB2 | MOB kinase activator 2. (268 aa) |
| | RPLP1 | Uncharacterized protein; Belongs to the eukaryotic ribosomal protein P1/P2 family. (114 aa) |
| | ENSNLEP00000027334 | Uncharacterized protein; Belongs to the eukaryotic ribosomal protein P1/P2 family. (92 aa) |
| | ENSNLEP00000027432 | TNF receptor-associated factor. (488 aa) |
| | SPRY2 | Sprouty RTK signaling antagonist 2. (338 aa) |
| | DDX3X | DEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (704 aa) |
| | DELE1 | DAP3 binding cell death enhancer 1. (536 aa) |
| | STK4 | Serine/threonine kinase 4. (490 aa) |
| | DLG1 | Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (916 aa) |
| | STRADA | STE20 related adaptor alpha. (431 aa) |
| | ENSNLEP00000029188 | Uncharacterized protein. (60 aa) |
| | TNFSF15 | Tumor necrosis factor ligand 1B. (251 aa) |
| | CALM1 | Calmodulin 1; Belongs to the calmodulin family. (150 aa) |
| | CCNT2 | Cyclin T2; Belongs to the cyclin family. (730 aa) |
| | ENSNLEP00000029829 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (66 aa) |
| | DUSP19 | Dual specificity phosphatase 19; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (218 aa) |
| | PRKAG2 | Protein kinase AMP-activated non-catalytic subunit gamma 2. (569 aa) |
| | IGF2 | IlGF domain-containing protein. (180 aa) |
| | RPTOR | Regulatory associated protein of MTOR complex 1. (1318 aa) |
| | ENSNLEP00000030944 | Prohibitin. (220 aa) |
| | ENSNLEP00000031088 | Protein kinase domain-containing protein. (557 aa) |
| | GRM5 | Glutamate metabotropic receptor 5. (1210 aa) |
| | ENSNLEP00000032143 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (108 aa) |
| | ITGB3 | Integrin beta; Belongs to the integrin beta chain family. (806 aa) |
| | LTF | Uncharacterized protein. (453 aa) |
| | LOC100579883 | BRCT domain-containing protein. (585 aa) |
| | OSBPL8 | Oxysterol-binding protein; Belongs to the OSBP family. (873 aa) |
| | ENSNLEP00000032876 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (133 aa) |
| | ZFP91 | Uncharacterized protein. (570 aa) |
| | ENSNLEP00000033820 | Protein kinase domain-containing protein. (407 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2578 aa) |
| | MAPK8IP2 | PID domain-containing protein. (178 aa) |
| | NTRK3 | Tyrosine-protein kinase receptor. (706 aa) |
| | TLR3 | Toll like receptor 3; Belongs to the Toll-like receptor family. (904 aa) |
| | CKS1B | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa) |
| | WNK4 | WNK lysine deficient protein kinase 4. (1037 aa) |
| | EPO | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (193 aa) |
| | IQGAP1 | IQ motif containing GTPase activating protein 1. (1657 aa) |
| | PRRC1 | Proline rich coiled-coil 1. (445 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa) |
| | ABL1 | Tyrosine-protein kinase. (1006 aa) |
| | PARP16 | Poly [ADP-ribose] polymerase. (207 aa) |
| | IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (135 aa) |
| | GLYAT | Glycine-N-acyltransferase. (296 aa) |
| | FAM20C | FAM20C golgi associated secretory pathway kinase. (551 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
