31 items (Nomascus leucogenys) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Your Input:
	ENSNLEP00000040637	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (166 aa)
	LOC100593010	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (459 aa)
	IL18	Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
	ADRA2B	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (391 aa)
	ENSNLEP00000034296	DJ-1_PfpI domain-containing protein. (133 aa)
	MTOR	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2578 aa)
	ENSNLEP00000032876	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (133 aa)
	OSBPL8	Oxysterol-binding protein; Belongs to the OSBP family. (873 aa)
	ENSNLEP00000031088	Protein kinase domain-containing protein. (557 aa)
	ENSNLEP00000029188	Uncharacterized protein. (60 aa)
	PINK1	Protein kinase domain-containing protein. (563 aa)
	ADRA2C	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (374 aa)
	PDGFB	Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (233 aa)
	NTRK3	Tyrosine-protein kinase receptor. (706 aa)
	GAS6	Growth arrest specific 6. (679 aa)
	FGF1	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
	LOC100592336	PH_3 domain-containing protein. (247 aa)
	DYNAP	Dynactin associated protein. (210 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
	PPIA	Peptidyl-prolyl cis-trans isomerase A, N-terminally processed; PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding; Belongs to the cyclophilin-type PPIase family. PPIase A subfamily. (165 aa)
	NTF3	Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (268 aa)
	INSR	Insulin receptor. (1232 aa)
	PRKCZ	Protein kinase C zeta. (507 aa)
	SRC	Tyrosine-protein kinase. (537 aa)
	IGF1	IlGF domain-containing protein. (196 aa)
	SLC1A1	Amino acid transporter. (457 aa)
	NRG1	Neuregulin 1. (713 aa)
	CCDC88A	Coiled-coil domain containing 88A. (1871 aa)
	ENSNLEP00000046123	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (136 aa)
	PARK7	Parkinsonism associated deglycase. (189 aa)
	ITGB1BP1	Integrin subunit beta 1 binding protein 1. (200 aa)

Your Current Organism:

Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADRA2B	ADRA2C	ENSNLEP00000037927	ENSNLEP00000022524	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.467
ADRA2C	ADRA2B	ENSNLEP00000022524	ENSNLEP00000037927	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.467
ENSNLEP00000029188	ENSNLEP00000031088	ENSNLEP00000029188	ENSNLEP00000031088	Uncharacterized protein.	Protein kinase domain-containing protein.	0.567
ENSNLEP00000029188	PINK1	ENSNLEP00000029188	ENSNLEP00000024309	Uncharacterized protein.	Protein kinase domain-containing protein.	0.567
ENSNLEP00000031088	ENSNLEP00000029188	ENSNLEP00000031088	ENSNLEP00000029188	Protein kinase domain-containing protein.	Uncharacterized protein.	0.567
ENSNLEP00000031088	ENSNLEP00000034296	ENSNLEP00000031088	ENSNLEP00000034296	Protein kinase domain-containing protein.	DJ-1_PfpI domain-containing protein.	0.567
ENSNLEP00000031088	PARK7	ENSNLEP00000031088	ENSNLEP00000043391	Protein kinase domain-containing protein.	Parkinsonism associated deglycase.	0.567
ENSNLEP00000034296	ENSNLEP00000031088	ENSNLEP00000034296	ENSNLEP00000031088	DJ-1_PfpI domain-containing protein.	Protein kinase domain-containing protein.	0.567
ENSNLEP00000034296	PINK1	ENSNLEP00000034296	ENSNLEP00000024309	DJ-1_PfpI domain-containing protein.	Protein kinase domain-containing protein.	0.567
FGF1	IGF1	ENSNLEP00000011873	ENSNLEP00000045069	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	IlGF domain-containing protein.	0.599
FGF1	PDGFB	ENSNLEP00000011873	ENSNLEP00000018484	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family.	0.405
GAS6	SRC	ENSNLEP00000012621	ENSNLEP00000048569	Growth arrest specific 6.	Tyrosine-protein kinase.	0.508
IGF1	FGF1	ENSNLEP00000045069	ENSNLEP00000011873	IlGF domain-containing protein.	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	0.599
IGF1	INSR	ENSNLEP00000045069	ENSNLEP00000000477	IlGF domain-containing protein.	Insulin receptor.	0.994
IGF1	LOC100593010	ENSNLEP00000045069	ENSNLEP00000040615	IlGF domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.418
IGF1	NTRK3	ENSNLEP00000045069	ENSNLEP00000013887	IlGF domain-containing protein.	Tyrosine-protein kinase receptor.	0.406
IGF1	PDGFB	ENSNLEP00000045069	ENSNLEP00000018484	IlGF domain-containing protein.	Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family.	0.934
IGF1	SRC	ENSNLEP00000045069	ENSNLEP00000048569	IlGF domain-containing protein.	Tyrosine-protein kinase.	0.722
IGF1	WNT5A	ENSNLEP00000045069	ENSNLEP00000008828	IlGF domain-containing protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.559
INSR	IGF1	ENSNLEP00000000477	ENSNLEP00000045069	Insulin receptor.	IlGF domain-containing protein.	0.994

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