STRINGSTRING
OXT OXT MMP2 MMP2 GPX4 GPX4 PENK PENK RARA RARA CCDC62 CCDC62 BCL2L11 BCL2L11 NCOR2 NCOR2 UCN UCN MMP15 MMP15 SLC6A4 SLC6A4 H2AZ2 H2AZ2 OGG1 OGG1 RAMP3 RAMP3 RUVBL2 RUVBL2 ESRRA ESRRA GHSR GHSR POU4F2 POU4F2 SOCS2 SOCS2 CTNNB1 CTNNB1 CYP19A1 CYP19A1 CASP9 CASP9 ENSNLEP00000032181 ENSNLEP00000032181 ENSNLEP00000032147 ENSNLEP00000032147 ADCYAP1R1 ADCYAP1R1 ENSNLEP00000030331 ENSNLEP00000030331 ENSNLEP00000029165 ENSNLEP00000029165 FGF10 FGF10 EZH2 EZH2 HTR5A HTR5A ENSNLEP00000028114 ENSNLEP00000028114 CD38 CD38 NRIP1 NRIP1 ENSNLEP00000027205 ENSNLEP00000027205 TACR1 TACR1 ENSNLEP00000026090 ENSNLEP00000026090 ENSNLEP00000025620 ENSNLEP00000025620 GPER1 GPER1 CDKN1B CDKN1B DNMT3A DNMT3A LCOR LCOR MYOG MYOG PTGS2 PTGS2 KIF18A KIF18A DHH DHH ENDOG ENDOG PTCH1 PTCH1 CYP1B1 CYP1B1 ESR1 ESR1 AIFM1 AIFM1 WNT8B WNT8B SSTR3 SSTR3 CCN2 CCN2 ESR2 ESR2 TGFB1 TGFB1 TACR3 TACR3 CALR CALR SLC34A1 SLC34A1 CRHBP CRHBP SFRP1 SFRP1 ASS1 ASS1 STAT3 STAT3 STAT5B STAT5B SRD5A1 SRD5A1 ALDH1A2 ALDH1A2 PAM PAM PDGFRB PDGFRB PTGFR PTGFR CCNA2 CCNA2 IHH IHH COL1A1 COL1A1 HNRNPD HNRNPD PDGFA PDGFA PCNA PCNA CSN1S1 CSN1S1 HPGD HPGD NCOA3 NCOA3 FAM210B FAM210B BMP7 BMP7 IGFBP2 IGFBP2 APOB APOB OXTR OXTR STRN3 STRN3 GHR GHR NR2F2 NR2F2 ZNF703 ZNF703 ENSNLEP00000045860 ENSNLEP00000045860 ENSNLEP00000044724 ENSNLEP00000044724 TH TH IGF1R IGF1R ENSNLEP00000044511 ENSNLEP00000044511 ENSNLEP00000044037 ENSNLEP00000044037 H2AZ1 H2AZ1 ITGA2 ITGA2 ENSNLEP00000042382 ENSNLEP00000042382 MBD2 MBD2 ENSNLEP00000041025 ENSNLEP00000041025 FOXA1 FOXA1 CASP8 CASP8 AREG AREG HSF1 HSF1 MAP1B MAP1B ENSNLEP00000038866 ENSNLEP00000038866 BAD BAD ENSNLEP00000037553 ENSNLEP00000037553 PPP1R9B PPP1R9B ENO2 ENO2 ENSNLEP00000035926 ENSNLEP00000035926 EGFR EGFR ENSNLEP00000034094 ENSNLEP00000034094 SSTR2 SSTR2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
OXTOxytocin/neurophysin I prepropeptide; Belongs to the vasopressin/oxytocin family. (124 aa)
MMP2Matrix metallopeptidase 2. (647 aa)
GPX4Glutathione peroxidase; Belongs to the glutathione peroxidase family. (233 aa)
PENKProenkephalin. (267 aa)
RARARetinoic acid receptor alpha. (458 aa)
CCDC62Coiled-coil domain containing 62. (684 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (198 aa)
NCOR2Nuclear receptor corepressor 2. (2373 aa)
UCNUrocortin. (124 aa)
MMP15Matrix metallopeptidase 15. (669 aa)
SLC6A4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (625 aa)
H2AZ2Histone H2A; Belongs to the histone H2A family. (128 aa)
OGG18-oxoguanine DNA glycosylase. (414 aa)
RAMP3Receptor activity modifying protein 3. (148 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa)
ESRRAEstrogen related receptor alpha. (422 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
POU4F2POU domain protein. (408 aa)
SOCS2Suppressor of cytokine signaling 2. (176 aa)
CTNNB1Catenin beta 1. (781 aa)
CYP19A1Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. (503 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (426 aa)
ENSNLEP00000032181Uncharacterized protein. (103 aa)
ENSNLEP00000032147Uncharacterized protein. (3186 aa)
ADCYAP1R1ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (500 aa)
ENSNLEP00000030331Uncharacterized protein. (367 aa)
ENSNLEP00000029165Histone H2A; Belongs to the histone H2A family. (89 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (746 aa)
HTR5A5-hydroxytryptamine receptor 5A. (357 aa)
ENSNLEP00000028114Uncharacterized protein. (405 aa)
CD38CD38 molecule. (300 aa)
NRIP1Nuclear receptor interacting protein 1. (1158 aa)
ENSNLEP00000027205Uncharacterized protein. (353 aa)
TACR1Tachykinin receptor 1. (406 aa)
ENSNLEP000000260903-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (258 aa)
ENSNLEP00000025620Uncharacterized protein. (154 aa)
GPER1G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (377 aa)
CDKN1BUncharacterized protein. (204 aa)
DNMT3ADNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (880 aa)
LCORLigand dependent nuclear receptor corepressor. (1559 aa)
MYOGMyogenin. (249 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
KIF18AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (898 aa)
DHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (396 aa)
ENDOGEndonuclease. (278 aa)
PTCH1Patched 1. (1446 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
AIFM1Apoptosis inducing factor mitochondria associated 1. (613 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
SSTR3Somatostatin receptor 3; Belongs to the G-protein coupled receptor 1 family. (418 aa)
CCN2Cellular communication network factor 2. (349 aa)
ESR2Estrogen receptor 2. (530 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
TACR3Tachykinin receptor 3; Belongs to the G-protein coupled receptor 1 family. (465 aa)
CALRCalreticulin. (417 aa)
SLC34A1Solute carrier family 34 member 1. (601 aa)
CRHBPCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (322 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
ASS1Uncharacterized protein. (412 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
STAT5BSignal transducer and activator of transcription. (650 aa)
SRD5A13-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (259 aa)
ALDH1A2Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (518 aa)
PAMPeptidylglycine alpha-amidating monooxygenase. (979 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
PTGFRProstaglandin F receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (431 aa)
IHHIndian hedgehog signaling molecule. (389 aa)
COL1A1Collagen type I alpha 1 chain. (1386 aa)
HNRNPDHeterogeneous nuclear ribonucleoprotein D. (355 aa)
PDGFAPlatelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
CSN1S1Casein alpha s1. (183 aa)
HPGD15-hydroxyprostaglandin dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (266 aa)
NCOA3Nuclear receptor coactivator. (1419 aa)
FAM210BDUF1279 domain-containing protein. (192 aa)
BMP7Bone morphogenetic protein 7. (430 aa)
IGFBP2Insulin like growth factor binding protein 2. (325 aa)
APOBApolipoprotein B. (4559 aa)
OXTROxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (389 aa)
STRN3Striatin 3. (797 aa)
GHRGrowth hormone receptor. (645 aa)
NR2F2Nuclear receptor subfamily 2 group F member 2. (414 aa)
ZNF703Zinc finger protein 703. (522 aa)
ENSNLEP00000045860Uncharacterized protein. (64 aa)
ENSNLEP00000044724Histone H2A; Belongs to the histone H2A family. (109 aa)
THTyrosine hydroxylase. (507 aa)
IGF1RTyrosine-protein kinase receptor. (1199 aa)
ENSNLEP00000044511POU domain protein. (242 aa)
ENSNLEP00000044037Histone H2A; Belongs to the histone H2A family. (115 aa)
H2AZ1Histone H2A; Belongs to the histone H2A family. (128 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1181 aa)
ENSNLEP00000042382Uncharacterized protein. (425 aa)
MBD2MBD domain-containing protein. (230 aa)
ENSNLEP00000041025Uncharacterized protein. (381 aa)
FOXA1Uncharacterized protein. (346 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (538 aa)
AREGEGF-like domain-containing protein. (274 aa)
HSF1HSF_DOMAIN domain-containing protein. (272 aa)
MAP1BMicrotubule associated protein 1B. (2370 aa)
ENSNLEP00000038866DUF1279 domain-containing protein. (188 aa)
BADUncharacterized protein. (82 aa)
ENSNLEP00000037553Uncharacterized protein. (100 aa)
PPP1R9BProtein phosphatase 1 regulatory subunit 9B. (813 aa)
ENO2Enolase 2. (434 aa)
ENSNLEP00000035926Histone H2A; Belongs to the histone H2A family. (118 aa)
EGFRReceptor protein-tyrosine kinase. (1206 aa)
ENSNLEP00000034094Uncharacterized protein. (313 aa)
SSTR2Somatostatin receptor 2; Belongs to the G-protein coupled receptor 1 family. (369 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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