STRINGSTRING
IL37 IL37 TNIP2 TNIP2 CD86 CD86 NOS1 NOS1 APOB APOB RPS6KB1 RPS6KB1 CCDC142 CCDC142 EDN1 EDN1 MAPKAPK2 MAPKAPK2 IL20 IL20 ATP4B ATP4B IL24 IL24 PRPF8 PRPF8 NOD2 NOD2 ELANE ELANE SPON2 SPON2 LYN LYN MAP2K7 MAP2K7 PENK PENK SBNO2 SBNO2 G1QLB3_NOMLE G1QLB3_NOMLE NOS2 NOS2 RARA RARA IL1A IL1A IL36G IL36G MAPK3 MAPK3 IL36RN IL36RN G1QN82_NOMLE G1QN82_NOMLE RIPK2 RIPK2 MAOB MAOB CACTIN CACTIN TBXA2R TBXA2R PTGIR PTGIR IRAK3 IRAK3 SCGB1A1 SCGB1A1 G1QTH6_NOMLE G1QTH6_NOMLE NFKBIA NFKBIA MTDH MTDH ERBIN ERBIN CD180 CD180 HAVCR2 HAVCR2 NOS3 NOS3 CD96 CD96 NLRP3 NLRP3 IL12B IL12B IL12A IL12A IRAK2 IRAK2 PTPN22 PTPN22 TIMP4 TIMP4 KCNJ8 KCNJ8 BPIFC BPIFC CD80 CD80 TREM2 TREM2 PLSCR4 PLSCR4 AKAP8 AKAP8 IRF3 IRF3 MYD88 MYD88 GHSR GHSR TRIB1 TRIB1 NFKBIL1 NFKBIL1 NR1H4 NR1H4 BPI BPI LBP LBP THPO THPO SLPI SLPI HPGD HPGD CLDN1 CLDN1 RHOA RHOA MAPKAPK3 MAPKAPK3 WNT5A WNT5A FN1 FN1 IL10RA IL10RA BTK BTK CASP9 CASP9 ARID5A ARID5A GATA1 GATA1 CXCL6 CXCL6 PF4V1 PF4V1 PPBP PPBP CXCL5 CXCL5 CXCL3 CXCL3 CXCL2 CXCL2 CXCL11 CXCL11 ALPL ALPL CXCL9 CXCL9 CXCL10 CXCL10 FOXP3 FOXP3 MPO MPO CXCL13 CXCL13 SERPINE1 SERPINE1 MALT1 MALT1 NOTCH1 NOTCH1 HNRNPA0 HNRNPA0 SLC11A1 SLC11A1 TNFRSF11A TNFRSF11A CNR2 CNR2 JAK2 JAK2 GFER GFER CD274 CD274 PDCD1LG2 PDCD1LG2 STAP1 STAP1 TNIP3 TNIP3 IL12RB2 IL12RB2 CD14 CD14 SIRPA SIRPA PLSCR3 PLSCR3 CD68 CD68 HCK HCK PTAFR PTAFR TNFRSF1B TNFRSF1B PTGFR PTGFR PELI1 PELI1 RPS6KA3 RPS6KA3 S100A9 S100A9 LOC101179385 LOC101179385 LOC100587124 LOC100587124 GFI1 GFI1 FCAR FCAR NLRP7 NLRP7 PLCG2 PLCG2 TNIP1 TNIP1 FER FER IRF8 IRF8 ZC3H12A ZC3H12A LY86 LY86 VCAM1 VCAM1 ANKRD1 ANKRD1 ASS1 ASS1 IDO1 IDO1 ABL1 ABL1 VIM VIM F2R F2R CSF2 CSF2 ACP5 ACP5 WDR83 WDR83 GCH1 GCH1 CDK19 CDK19 AKIRIN2 AKIRIN2 ADAMTS13 ADAMTS13 TICAM1 TICAM1 PALM3 PALM3 NFKB1 NFKB1 ADAM17 ADAM17 PTGER1 PTGER1 TGFB1 TGFB1 ADH5 ADH5 NOCT NOCT CCL5 CCL5 LOXL1 LOXL1 ARG1 ARG1 SNCA SNCA ZFP36 ZFP36 PAF1 PAF1 SPI1 SPI1 G1RWX7_NOMLE G1RWX7_NOMLE CSF2RB CSF2RB TNFAIP3 TNFAIP3 DEFA6 DEFA6 DEFA4 DEFA4 LOC100595156 LOC100595156 DEFA5 DEFA5 CEBPE CEBPE SELP SELP FMO1 FMO1 PCK2 PCK2 FASLG FASLG TNFSF4 TNFSF4 TAB2 TAB2 AKAP12 AKAP12 PDCD4 PDCD4 P2RX7 P2RX7 TSPO TSPO ACOD1 ACOD1 PYCARD PYCARD PLAA PLAA EDNRB EDNRB PTGER4 PTGER4 NUGGC NUGGC PRKCE PRKCE FGFR2 FGFR2 SRR SRR CYP27B1 CYP27B1 CDK4 CDK4 SHPK SHPK ABCA1 ABCA1 IL18BP IL18BP ADM ADM CTR9 CTR9 NR4A1 NR4A1 TRAF6 TRAF6 PTGS2 PTGS2 CDC73 CDC73 CITED1 CITED1 BDKRB1 BDKRB1 G1SB02_NOMLE G1SB02_NOMLE PPARD PPARD LOC100586923 LOC100586923 MAPK14 MAPK14 CHMP5 CHMP5 TLR4 TLR4 ENSNLEP00000025620 ENSNLEP00000025620 KMO KMO MAPK10 MAPK10 NR1D1 NR1D1 NR1H3 NR1H3 ENSNLEP00000027205 ENSNLEP00000027205 MAPK1 MAPK1 ENSNLEP00000027432 ENSNLEP00000027432 UMOD UMOD CD6 CD6 CPS1 CPS1 AKT1 AKT1 ENSNLEP00000028114 ENSNLEP00000028114 PDE4B PDE4B ENSNLEP00000028316 ENSNLEP00000028316 FGF10 FGF10 CSF3 CSF3 CTSG CTSG LOC100580967 LOC100580967 BCL2L2-PABPN1 BCL2L2-PABPN1 LIAS LIAS PCSK1 PCSK1 ADAM9 ADAM9 ENSNLEP00000030421 ENSNLEP00000030421 LY96 LY96 AICDA AICDA THBD THBD SBNO2-2 SBNO2-2 DIO2 DIO2 IL10 IL10 ENSNLEP00000034094 ENSNLEP00000034094 MEF2C MEF2C LITAF LITAF FOXP1 FOXP1 RELA RELA ENSNLEP00000036737 ENSNLEP00000036737 LDOC1 LDOC1 GJB6 GJB6 ENSNLEP00000037553 ENSNLEP00000037553 OTUD5 OTUD5 SELE SELE IL18 IL18 HDAC2 HDAC2 HSF1 HSF1 ENSNLEP00000039390 ENSNLEP00000039390 CASP8 CASP8 BCL10 BCL10 IFNAR1 IFNAR1 ENSNLEP00000040898 ENSNLEP00000040898 ENSNLEP00000041025 ENSNLEP00000041025 ABCC8 ABCC8 EFNB2 EFNB2 GIT1 GIT1 UPF1 UPF1 MAP2K3 MAP2K3 ENSNLEP00000041971 ENSNLEP00000041971 EPHB2 EPHB2 CX3CR1 CX3CR1 TJP1 TJP1 ENSNLEP00000042382 ENSNLEP00000042382 ICOSLG ICOSLG XBP1 XBP1 PF4 PF4 TRIM41 TRIM41 ENSNLEP00000043509 ENSNLEP00000043509 SCARB1 SCARB1 TIRAP TIRAP IL23R IL23R SELENOS SELENOS ENSNLEP00000044067 ENSNLEP00000044067 ENSNLEP00000044505 ENSNLEP00000044505 CASP1 CASP1 TH TH CCR7 CCR7 DAB2IP DAB2IP IL1B IL1B CD36 CD36 ENSNLEP00000045860 ENSNLEP00000045860 SLC7A5 SLC7A5 MAPK8 MAPK8 CXCL8 CXCL8 CMPK2 CMPK2 BCR BCR S100A14 S100A14 ENSNLEP00000047116 ENSNLEP00000047116 IL6 IL6 HMGCS2 HMGCS2 S100A8 S100A8 ENSNLEP00000047342 ENSNLEP00000047342 FOS FOS DUSP10 DUSP10 TNF TNF AXL AXL ENSNLEP00000048177 ENSNLEP00000048177 SRC SRC CAPN2 CAPN2 PTGER2 PTGER2 SMAD6 SMAD6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IL37Interleukin-1. (218 aa)
TNIP2CCHC NOA-type domain-containing protein. (322 aa)
CD86CD86 molecule. (329 aa)
NOS1Nitric oxide synthase; Produces nitric oxide (NO). (1425 aa)
APOBApolipoprotein B. (4559 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (513 aa)
CCDC142Coiled-coil domain containing 142. (749 aa)
EDN1Endothelin 1. (211 aa)
MAPKAPK2MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (370 aa)
IL20Interleukin 20. (176 aa)
ATP4BATPase H+/K+ transporting subunit beta. (237 aa)
IL24Interleukin 24. (207 aa)
PRPF8Pre-mRNA processing factor 8. (2279 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1040 aa)
ELANEElastase, neutrophil expressed; Belongs to the peptidase S1 family. (239 aa)
SPON2Spondin 2. (330 aa)
LYNTyrosine-protein kinase. (512 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (391 aa)
PENKProenkephalin. (267 aa)
SBNO2Strawberry notch homolog 2. (1252 aa)
G1QLB3_NOMLEC-C motif chemokine. (138 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1153 aa)
RARARetinoic acid receptor alpha. (458 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (247 aa)
IL36GInterleukin-1. (169 aa)
MAPK3Mitogen-activated protein kinase. (278 aa)
IL36RNInterleukin-1. (155 aa)
G1QN82_NOMLEInterleukin-1. (129 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
MAOBAmine oxidase. (520 aa)
CACTINUncharacterized protein. (625 aa)
TBXA2RThromboxane A2 receptor; Belongs to the G-protein coupled receptor 1 family. (407 aa)
PTGIRProstaglandin I2 receptor; Belongs to the G-protein coupled receptor 1 family. (386 aa)
IRAK3Interleukin 1 receptor associated kinase 3. (596 aa)
SCGB1A1Secretoglobin family 1A member 1. (91 aa)
G1QTH6_NOMLEUncharacterized protein. (222 aa)
NFKBIANFKB inhibitor alpha. (305 aa)
MTDHMetadherin. (582 aa)
ERBINErbb2 interacting protein. (1418 aa)
CD180CD180 molecule. (661 aa)
HAVCR2Hepatitis A virus cellular receptor 2. (302 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1128 aa)
CD96CD96 molecule. (586 aa)
NLRP3NLR family pyrin domain containing 3. (1020 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (328 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (203 aa)
IRAK2Interleukin 1 receptor associated kinase 2. (568 aa)
PTPN22Protein tyrosine phosphatase non-receptor type 22. (807 aa)
TIMP4TIMP metallopeptidase inhibitor 4. (224 aa)
KCNJ8Potassium voltage-gated channel subfamily J member 8. (424 aa)
BPIFCBPI fold containing family C. (507 aa)
CD80CD80 molecule. (288 aa)
TREM2Ig-like domain-containing protein. (222 aa)
PLSCR4Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (329 aa)
AKAP8A-kinase anchoring protein 8; Belongs to the AKAP95 family. (692 aa)
IRF3IRF tryptophan pentad repeat domain-containing protein. (301 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (317 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
TRIB1Tribbles pseudokinase 1. (321 aa)
NFKBIL1NFKB inhibitor like 1. (358 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (486 aa)
BPIBactericidal permeability increasing protein. (487 aa)
LBPLipopolysaccharide binding protein. (481 aa)
THPOThrombopoietin. (353 aa)
SLPISecretory leukocyte peptidase inhibitor. (132 aa)
HPGD15-hydroxyprostaglandin dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (266 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
RHOARas homolog family member A. (193 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (382 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
FN1Fibronectin 1. (2477 aa)
IL10RAInterleukin 10 receptor subunit alpha. (557 aa)
BTKTyrosine-protein kinase. (659 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (426 aa)
ARID5AAT-rich interaction domain 5A. (599 aa)
GATA1GATA binding protein 1. (413 aa)
CXCL6C-X-C motif chemokine. (114 aa)
PF4V1C-X-C motif chemokine. (101 aa)
PPBPC-X-C motif chemokine. (128 aa)
CXCL5C-X-C motif chemokine. (114 aa)
CXCL3C-X-C motif chemokine. (107 aa)
CXCL2C-X-C motif chemokine. (106 aa)
CXCL11C-X-C motif chemokine. (94 aa)
ALPLAlkaline phosphatase. (524 aa)
CXCL9C-X-C motif chemokine. (125 aa)
CXCL10C-X-C motif chemokine. (98 aa)
FOXP3Forkhead box P3. (455 aa)
MPOMyeloperoxidase. (745 aa)
CXCL13C-X-C motif chemokine ligand 13. (109 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (402 aa)
MALT1MALT1 paracaspase. (824 aa)
NOTCH1Notch receptor 1. (2451 aa)
HNRNPA0Heterogeneous nuclear ribonucleoprotein A0. (311 aa)
SLC11A1Solute carrier family 11 member 1. (550 aa)
TNFRSF11ATNF receptor superfamily member 11a. (595 aa)
CNR2Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. (360 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
GFERSulfhydryl oxidase. (205 aa)
CD274CD274 molecule. (290 aa)
PDCD1LG2Programmed cell death 1 ligand 2. (273 aa)
STAP1Signal transducing adaptor family member 1. (295 aa)
TNIP3TNFAIP3 interacting protein 3. (376 aa)
IL12RB2Interleukin 12 receptor subunit beta 2. (862 aa)
CD14Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (375 aa)
SIRPAUncharacterized protein. (486 aa)
PLSCR3Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (295 aa)
CD68CD68 molecule. (354 aa)
HCKTyrosine-protein kinase. (525 aa)
PTAFRPlatelet activating factor receptor; Belongs to the G-protein coupled receptor 1 family. (342 aa)
TNFRSF1BTNF receptor superfamily member 1B. (424 aa)
PTGFRProstaglandin F receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
RPS6KA3Ribosomal protein S6 kinase. (732 aa)
S100A9Protein S100; Belongs to the S-100 family. (112 aa)
LOC101179385Protein S100; Belongs to the S-100 family. (101 aa)
LOC100587124Protein S100; Belongs to the S-100 family. (101 aa)
GFI1Growth factor independent 1 transcriptional repressor. (403 aa)
FCARFc fragment of IgA receptor. (268 aa)
NLRP7NLR family pyrin domain containing 7. (969 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1218 aa)
TNIP1TNFAIP3 interacting protein 1. (619 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
IRF8Interferon regulatory factor 8. (426 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (560 aa)
LY86Lymphocyte antigen 86. (162 aa)
VCAM1Vascular cell adhesion molecule 1. (739 aa)
ANKRD1Ankyrin repeat domain 1. (286 aa)
ASS1Uncharacterized protein. (412 aa)
IDO1Indoleamine 2,3-dioxygenase 1. (402 aa)
ABL1Tyrosine-protein kinase. (1006 aa)
VIMIF rod domain-containing protein; Belongs to the intermediate filament family. (228 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (425 aa)
CSF2Colony stimulating factor 2. (144 aa)
ACP5Tartrate-resistant acid phosphatase type 5. (325 aa)
WDR83WD repeat domain 83. (320 aa)
GCH1GTP cyclohydrolase 1. (250 aa)
CDK19Cyclin dependent kinase 19. (481 aa)
AKIRIN2Akirin 2. (203 aa)
ADAMTS13ADAM metallopeptidase with thrombospondin type 1 motif 13. (1359 aa)
TICAM1TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (691 aa)
PALM3Paralemmin 3. (654 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
ADAM17ADAM metallopeptidase domain 17. (824 aa)
PTGER1Prostaglandin E receptor 1. (381 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
ADH5S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (383 aa)
NOCTNocturnin. (368 aa)
CCL5C-C motif chemokine. (91 aa)
LOXL1Lysyl oxidase like 1. (577 aa)
ARG1Arginase. (322 aa)
SNCAAlpha-synuclein; Belongs to the synuclein family. (140 aa)
ZFP36ZFP36 ring finger protein. (322 aa)
PAF1PAF1 homolog, Paf1/RNA polymerase II complex component. (535 aa)
SPI1Spi-1 proto-oncogene. (271 aa)
G1RWX7_NOMLEANK_REP_REGION domain-containing protein. (182 aa)
CSF2RBColony stimulating factor 2 receptor beta common subunit. (903 aa)
TNFAIP3TNF alpha induced protein 3. (790 aa)
DEFA6Defensin alpha 6. (100 aa)
DEFA4Defensin alpha 4. (97 aa)
LOC100595156DEFENSIN domain-containing protein. (99 aa)
DEFA5Defensin alpha 5. (94 aa)
CEBPECCAAT/enhancer-binding protein. (281 aa)
SELPSelectin P. (830 aa)
FMO1Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (575 aa)
FASLGTumor necrosis factor ligand 1A; Belongs to the tumor necrosis factor family. (280 aa)
TNFSF4Tumor necrosis factor ligand 2B; Belongs to the tumor necrosis factor family. (183 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
AKAP12A-kinase anchoring protein 12. (1779 aa)
PDCD4Programmed cell death 4. (470 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
TSPOTranslocator protein. (169 aa)
ACOD1Aconitate decarboxylase 1. (489 aa)
PYCARDPYD and CARD domain containing. (195 aa)
PLAAPhospholipase A2 activating protein. (764 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (532 aa)
PTGER4Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (490 aa)
NUGGCNuclear GTPase, germinal center associated. (796 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
FGFR2Fibroblast growth factor receptor. (820 aa)
SRRSerine racemase. (340 aa)
CYP27B1Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (508 aa)
CDK4Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
SHPKFGGY_N domain-containing protein. (418 aa)
ABCA1ATP binding cassette subfamily A member 1. (2254 aa)
IL18BPInterleukin 18 binding protein. (194 aa)
ADMAdrenomedullin. (184 aa)
CTR9CTR9 homolog, Paf1/RNA polymerase II complex component. (1173 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1. (589 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
CDC73Cell division cycle 73. (531 aa)
CITED1Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (219 aa)
BDKRB1G_PROTEIN_RECEP_F1_2 domain-containing protein. (284 aa)
G1SB02_NOMLEDUF4939 domain-containing protein. (94 aa)
PPARDPeroxisome proliferator activated receptor delta. (441 aa)
LOC100586923Uncharacterized protein. (695 aa)
MAPK14Mitogen-activated protein kinase. (321 aa)
CHMP5Charged multivesicular body protein 5. (219 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (832 aa)
ENSNLEP00000025620Uncharacterized protein. (154 aa)
KMOKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. (486 aa)
MAPK10Mitogen-activated protein kinase. (550 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (574 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (466 aa)
ENSNLEP00000027205Uncharacterized protein. (353 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (341 aa)
ENSNLEP00000027432TNF receptor-associated factor. (488 aa)
UMODUromodulin. (676 aa)
CD6CD6 molecule. (668 aa)
CPS1Carbamoyl-phosphate synthase 1. (1506 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa)
ENSNLEP00000028114Uncharacterized protein. (405 aa)
PDE4BPhosphodiesterase. (736 aa)
ENSNLEP00000028316ADH_N domain-containing protein. (91 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
CSF3Colony stimulating factor 3. (207 aa)
CTSGCathepsin G; Belongs to the peptidase S1 family. (255 aa)
LOC100580967DEFENSIN domain-containing protein. (108 aa)
BCL2L2-PABPN1BCL2L2-PABPN1 readthrough. (333 aa)
LIASLipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (372 aa)
PCSK1Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (744 aa)
ADAM9ADAM metallopeptidase domain 9. (819 aa)
ENSNLEP00000030421Uncharacterized protein. (190 aa)
LY96Lymphocyte antigen 96. (160 aa)
AICDAActivation induced cytidine deaminase. (202 aa)
THBDThrombomodulin. (568 aa)
SBNO2-2Uncharacterized protein. (56 aa)
DIO2Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). (145 aa)
IL10Interleukin 10. (178 aa)
ENSNLEP00000034094Uncharacterized protein. (313 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
LITAFLITAF domain-containing protein. (222 aa)
FOXP1Forkhead box P1. (693 aa)
RELARELA proto-oncogene, NF-kB subunit. (551 aa)
ENSNLEP00000036737Uncharacterized protein. (160 aa)
LDOC1LDOC1 regulator of NFKB signaling. (145 aa)
GJB6Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (261 aa)
ENSNLEP00000037553Uncharacterized protein. (100 aa)
OTUD5OTU deubiquitinase 5. (542 aa)
SELESelectin E. (612 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (533 aa)
HSF1HSF_DOMAIN domain-containing protein. (272 aa)
ENSNLEP00000039390Protein kinase domain-containing protein. (673 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (538 aa)
BCL10CARD domain-containing protein. (319 aa)
IFNAR1Interferon alpha and beta receptor subunit 1. (557 aa)
ENSNLEP00000040898Uncharacterized protein. (411 aa)
ENSNLEP00000041025Uncharacterized protein. (381 aa)
ABCC8ATP binding cassette subfamily C member 8. (1569 aa)
EFNB2Ephrin B2; Belongs to the ephrin family. (299 aa)
GIT1GIT ArfGAP 1. (772 aa)
UPF1UPF1 RNA helicase and ATPase. (996 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (317 aa)
ENSNLEP00000041971Uncharacterized protein. (346 aa)
EPHB2EPH receptor B2. (1015 aa)
CX3CR1C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (386 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1754 aa)
ENSNLEP00000042382Uncharacterized protein. (425 aa)
ICOSLGUncharacterized protein. (411 aa)
XBP1BZIP domain-containing protein. (376 aa)
PF4C-X-C motif chemokine. (106 aa)
TRIM41Tripartite motif containing 41. (585 aa)
ENSNLEP00000043509ADH_N domain-containing protein. (159 aa)
SCARB1Scavenger receptor class B member 1; Belongs to the CD36 family. (550 aa)
TIRAPTIR domain containing adaptor protein. (221 aa)
IL23RInterleukin 23 receptor. (629 aa)
SELENOSUncharacterized protein. (218 aa)
ENSNLEP00000044067Uncharacterized protein. (108 aa)
ENSNLEP00000044505RRM domain-containing protein. (254 aa)
CASP1Caspase 1; Belongs to the peptidase C14A family. (404 aa)
THTyrosine hydroxylase. (507 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa)
DAB2IPDAB2 interacting protein. (1159 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa)
CD36CD36 molecule; Belongs to the CD36 family. (433 aa)
ENSNLEP00000045860Uncharacterized protein. (64 aa)
SLC7A5Solute carrier family 7 member 5. (507 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
CMPK2Thymidylate_kin domain-containing protein. (379 aa)
BCRBCR activator of RhoGEF and GTPase. (1271 aa)
S100A14S100 calcium binding protein A14; Belongs to the S-100 family. (104 aa)
ENSNLEP00000047116RRM domain-containing protein. (125 aa)
IL6Uncharacterized protein. (258 aa)
HMGCS23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa)
S100A8Protein S100; Belongs to the S-100 family. (93 aa)
ENSNLEP00000047342C-X-C motif chemokine. (94 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
DUSP10Dual specificity phosphatase 10. (482 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
AXLReceptor protein-tyrosine kinase. (860 aa)
ENSNLEP00000048177Defensin_propep domain-containing protein. (94 aa)
SRCTyrosine-protein kinase. (537 aa)
CAPN2Calpain 2; Belongs to the peptidase C2 family. (660 aa)
PTGER2Prostaglandin E receptor 2; Belongs to the G-protein coupled receptor 1 family. (340 aa)
SMAD6Mothers against decapentaplegic homolog. (465 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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