STRINGSTRING
TGFB1 TGFB1 OXTR OXTR PTGER2 PTGER2 FOS FOS UBE3A UBE3A IGF1R IGF1R THBS1 THBS1 ENSNLEP00000042687 ENSNLEP00000042687 BAD BAD WBP2 WBP2 ENSNLEP00000032543 ENSNLEP00000032543 CAV1 CAV1 YAP1 YAP1 SREBF1 SREBF1 CD38 CD38 NR1H3 NR1H3 TACR1 TACR1 SOX10 SOX10 CLDN4 CLDN4 GABRB1 GABRB1 TGFB3 TGFB3 CYP1B1 CYP1B1 ACOD1 ACOD1 TSPO TSPO TGFB2 TGFB2 SRC SRC ABHD2 ABHD2 NCOA2 NCOA2 NKX2-2 NKX2-2 CSN1S1 CSN1S1 OXT OXT TYMS TYMS DSG1 DSG1 FOSL1 FOSL1 TRERF1 TRERF1 FOSB FOSB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
OXTROxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (389 aa)
PTGER2Prostaglandin E receptor 2; Belongs to the G-protein coupled receptor 1 family. (340 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (881 aa)
IGF1RTyrosine-protein kinase receptor. (1199 aa)
THBS1Thrombospondin 1. (1173 aa)
ENSNLEP00000042687Uncharacterized protein. (245 aa)
BADUncharacterized protein. (82 aa)
WBP2WW domain binding protein 2. (260 aa)
ENSNLEP00000032543Uncharacterized protein. (168 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
YAP1Uncharacterized protein. (418 aa)
SREBF1Sterol regulatory element binding transcription factor 1. (1147 aa)
CD38CD38 molecule. (300 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (466 aa)
TACR1Tachykinin receptor 1. (406 aa)
SOX10HMG box domain-containing protein. (236 aa)
CLDN4Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa)
GABRB1Gamma-aminobutyric acid type A receptor beta1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (474 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa)
ACOD1Aconitate decarboxylase 1. (489 aa)
TSPOTranslocator protein. (169 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
SRCTyrosine-protein kinase. (537 aa)
ABHD2Abhydrolase domain containing 2. (437 aa)
NCOA2Nuclear receptor coactivator. (1464 aa)
NKX2-2NK2 homeobox 2. (273 aa)
CSN1S1Casein alpha s1. (183 aa)
OXTOxytocin/neurophysin I prepropeptide; Belongs to the vasopressin/oxytocin family. (124 aa)
TYMSThymidylat_synt domain-containing protein. (173 aa)
DSG1Desmoglein 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1046 aa)
FOSL1BZIP domain-containing protein. (271 aa)
TRERF1Transcriptional regulating factor 1. (1218 aa)
FOSBFosB proto-oncogene, AP-1 transcription factor subunit. (338 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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