STRINGSTRING
NTRK1 NTRK1 CHRNA4 CHRNA4 TACR1 TACR1 MAPK1 MAPK1 ENSNLEP00000031077 ENSNLEP00000031077 HOMER1 HOMER1 RELA RELA BCL2 BCL2 PPP1R9B PPP1R9B B2M B2M GABBR1 GABBR1 BAD BAD HDAC2 HDAC2 LOC105739044 LOC105739044 ENSNLEP00000041886 ENSNLEP00000041886 IGF1R IGF1R TH TH HMOX1 HMOX1 CHRNA2 CHRNA2 TNF TNF GNAT3 GNAT3 NFKB1 NFKB1 CHRNB3 CHRNB3 VCAM1 VCAM1 CHRNB2 CHRNB2 SLC6A3 SLC6A3 ABAT ABAT NKX6-1 NKX6-1 CHRNB4 CHRNB4 CHRNA3 CHRNA3 CHRNA5 CHRNA5 LYPD1 LYPD1 CHRNA7 CHRNA7 AVP AVP GRM2 GRM2 PENK PENK MMP2 MMP2 EDN1 EDN1 PPARA PPARA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NTRK1Tyrosine-protein kinase receptor. (787 aa)
CHRNA4Cholinergic receptor nicotinic alpha 4 subunit. (587 aa)
TACR1Tachykinin receptor 1. (406 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (341 aa)
ENSNLEP00000031077Neur_chan_LBD domain-containing protein. (158 aa)
HOMER1Homer scaffold protein 1. (377 aa)
RELARELA proto-oncogene, NF-kB subunit. (551 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
PPP1R9BProtein phosphatase 1 regulatory subunit 9B. (813 aa)
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (119 aa)
GABBR1G_PROTEIN_RECEP_F3_4 domain-containing protein. (281 aa)
BADUncharacterized protein. (82 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (533 aa)
LOC105739044Sushi domain-containing protein. (98 aa)
ENSNLEP00000041886Ion_trans domain-containing protein; Belongs to the potassium channel family. (359 aa)
IGF1RTyrosine-protein kinase receptor. (1199 aa)
THTyrosine hydroxylase. (507 aa)
HMOX1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (288 aa)
CHRNA2Cholinergic receptor nicotinic alpha 2 subunit. (529 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
GNAT3G protein subunit alpha transducin 3. (354 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
CHRNB3Cholinergic receptor nicotinic beta 3 subunit. (458 aa)
VCAM1Vascular cell adhesion molecule 1. (739 aa)
CHRNB2Uncharacterized protein. (329 aa)
SLC6A3Solute carrier family 6 member 3. (552 aa)
ABAT4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (516 aa)
NKX6-1NK6 homeobox 1. (368 aa)
CHRNB4Cholinergic receptor nicotinic beta 4 subunit. (448 aa)
CHRNA3Cholinergic receptor nicotinic alpha 3 subunit. (503 aa)
CHRNA5Cholinergic receptor nicotinic alpha 5 subunit. (455 aa)
LYPD1LY6/PLAUR domain containing 1. (141 aa)
CHRNA7Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (358 aa)
AVPArginine vasopressin; Belongs to the vasopressin/oxytocin family. (164 aa)
GRM2Glutamate metabotropic receptor 2. (873 aa)
PENKProenkephalin. (267 aa)
MMP2Matrix metallopeptidase 2. (647 aa)
EDN1Endothelin 1. (211 aa)
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.