STRINGSTRING
EDNRB EDNRB HTR1B HTR1B HTR7 HTR7 CD38 CD38 SLC8A1 SLC8A1 CAV1 CAV1 RAP1GDS1 RAP1GDS1 ENSNLEP00000036737 ENSNLEP00000036737 TRPM4 TRPM4 HTR2A HTR2A EDN3 EDN3 ADRA1A ADRA1A DBH DBH CRP CRP SMTNL1 SMTNL1 EDN2 EDN2 AVP AVP RHOA RHOA COMP COMP EDNRA EDNRA GRIP2 GRIP2 SLC6A4 SLC6A4 KEL KEL BBS2 BBS2 AGT AGT EDN1 EDN1 BDKRB2 BDKRB2 HTR2B HTR2B MKKS MKKS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (532 aa)
HTR1B5-hydroxytryptamine receptor 1B. (390 aa)
HTR7G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (325 aa)
CD38CD38 molecule. (300 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (972 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
RAP1GDS1Rap1 GTPase-GDP dissociation stimulator 1. (626 aa)
ENSNLEP00000036737Uncharacterized protein. (160 aa)
TRPM4Uncharacterized protein. (1010 aa)
HTR2A5-hydroxytryptamine receptor 2A. (471 aa)
EDN3Uncharacterized protein. (211 aa)
ADRA1AAdrenoceptor alpha 1A. (470 aa)
DBHDopamine beta-hydroxylase. (611 aa)
CRPPentaxin. (224 aa)
SMTNL1Smoothelin like 1. (493 aa)
EDN2Endothelin 2. (177 aa)
AVPArginine vasopressin; Belongs to the vasopressin/oxytocin family. (164 aa)
RHOARas homolog family member A. (193 aa)
COMPTSP C-terminal domain-containing protein. (194 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
GRIP2Glutamate receptor interacting protein 2. (1142 aa)
SLC6A4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (625 aa)
KELKell metallo-endopeptidase (Kell blood group). (720 aa)
BBS2Bardet-Biedl syndrome 2 protein homolog. (721 aa)
AGTAngiotensinogen; Belongs to the serpin family. (485 aa)
EDN1Endothelin 1. (211 aa)
BDKRB2Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. (386 aa)
HTR2BG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (398 aa)
MKKSMcKusick-Kaufman syndrome. (570 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.