STRINGSTRING
LRP2 LRP2 PDE3A PDE3A SULT2B1 SULT2B1 NPR2 NPR2 GUCY2C GUCY2C CMKLR1 CMKLR1 C2CD2L C2CD2L LHCGR LHCGR CTSH CTSH CRHBP CRHBP CALR CALR ATP1A3 ATP1A3 NPR3 NPR3 CRHR2 CRHR2 GHRHR GHRHR CALCR CALCR TSPO TSPO EDNRB EDNRB CCKAR CCKAR SEC61B SEC61B AVPR1A AVPR1A AMHR2 AMHR2 MC4R MC4R MC3R MC3R NR3C1 NR3C1 GPER1 GPER1 RAMP1 RAMP1 THRB THRB VIPR1 VIPR1 ADCYAP1R1 ADCYAP1R1 PTH2R PTH2R PIK3R1 PIK3R1 ATP1A1 ATP1A1 CCKBR CCKBR CRYM CRYM TTR TTR EGFR EGFR PRLR PRLR LEPR LEPR ENSNLEP00000039370 ENSNLEP00000039370 ENSNLEP00000041416 ENSNLEP00000041416 IDE IDE IGF1R IGF1R ENSNLEP00000046563 ENSNLEP00000046563 FSHR FSHR GALR1 GALR1 GCGR GCGR SCTR SCTR NPR1 NPR1 GLP1R GLP1R ABHD2 ABHD2 SHC1 SHC1 RAMP2 RAMP2 MLNR MLNR HCRTR2 HCRTR2 INHBA INHBA EBI3 EBI3 ADIPOR2 ADIPOR2 ADIPOR1 ADIPOR1 GLP2R GLP2R OXTR OXTR ATP1A2 ATP1A2 GHR GHR GALR2 GALR2 HCRTR1 HCRTR1 VIPR2 VIPR2 THRA THRA ALDH1A1 ALDH1A1 ALDH1A3 ALDH1A3 ACVR1 ACVR1 AR AR AVPR1B AVPR1B INSR INSR CALCRL CALCRL SLC40A1 SLC40A1 PTH1R PTH1R GHSR GHSR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LRP2LDL receptor related protein 2. (4624 aa)
PDE3APhosphodiesterase. (1141 aa)
SULT2B1Sulfotransferase; Belongs to the sulfotransferase 1 family. (358 aa)
NPR2Guanylate cyclase. (1038 aa)
GUCY2CGuanylate cyclase. (1073 aa)
CMKLR1Chemerin chemokine-like receptor 1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
C2CD2LC2CD2 like. (716 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (701 aa)
CTSHCathepsin H; Belongs to the peptidase C1 family. (335 aa)
CRHBPCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (322 aa)
CALRCalreticulin. (417 aa)
ATP1A3Sodium/potassium-transporting ATPase subunit alpha. (952 aa)
NPR3Natriuretic peptide receptor 3. (537 aa)
CRHR2Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family. (437 aa)
GHRHRGrowth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (424 aa)
CALCRCalcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (509 aa)
TSPOTranslocator protein. (169 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (532 aa)
CCKARCholecystokinin A receptor; Belongs to the G-protein coupled receptor 1 family. (428 aa)
SEC61BProtein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (96 aa)
AVPR1AVasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. (405 aa)
AMHR2Anti-Muellerian hormone type-2 receptor; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. (573 aa)
MC4RMelanocortin 4 receptor. (332 aa)
MC3RMelanocortin 3 receptor. (323 aa)
NR3C1Nuclear receptor subfamily 3 group C member 1. (778 aa)
GPER1G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (377 aa)
RAMP1Receptor activity modifying protein 1. (148 aa)
THRBUncharacterized protein. (476 aa)
VIPR1Vasoactive intestinal peptide receptor 1; Belongs to the G-protein coupled receptor 2 family. (427 aa)
ADCYAP1R1ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (500 aa)
PTH2RParathyroid hormone 2 receptor; Belongs to the G-protein coupled receptor 2 family. (550 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (716 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1027 aa)
CCKBRG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (514 aa)
CRYMCrystallin mu. (293 aa)
TTRTransthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. (163 aa)
EGFRReceptor protein-tyrosine kinase. (1206 aa)
PRLRProlactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (622 aa)
LEPRLeptin receptor. (1165 aa)
ENSNLEP00000039370SH2 domain-containing protein. (299 aa)
ENSNLEP00000041416Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (92 aa)
IDEInsulin degrading enzyme. (976 aa)
IGF1RTyrosine-protein kinase receptor. (1199 aa)
ENSNLEP00000046563Uncharacterized protein. (498 aa)
FSHRFollicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (695 aa)
GALR1Galanin receptor 1; Belongs to the G-protein coupled receptor 1 family. (349 aa)
GCGRGlucagon receptor; Belongs to the G-protein coupled receptor 2 family. (477 aa)
SCTRSecretin receptor; Belongs to the G-protein coupled receptor 2 family. (440 aa)
NPR1Guanylate cyclase. (914 aa)
GLP1RGlucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (462 aa)
ABHD2Abhydrolase domain containing 2. (437 aa)
SHC1SHC adaptor protein 1. (542 aa)
RAMP2Receptor activity modifying protein 2. (180 aa)
MLNRMotilin receptor; Belongs to the G-protein coupled receptor 1 family. (412 aa)
HCRTR2Hypocretin receptor 2; Belongs to the G-protein coupled receptor 1 family. (444 aa)
INHBAInhibin subunit beta A. (426 aa)
EBI3Epstein-Barr virus induced 3. (193 aa)
ADIPOR2Adiponectin receptor 2. (386 aa)
ADIPOR1Adiponectin receptor 1. (369 aa)
GLP2RGlucagon like peptide 2 receptor; Belongs to the G-protein coupled receptor 2 family. (553 aa)
OXTROxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (389 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
GHRGrowth hormone receptor. (645 aa)
GALR2Galanin receptor 2; Belongs to the G-protein coupled receptor 1 family. (387 aa)
HCRTR1Hypocretin receptor 1; Belongs to the G-protein coupled receptor 1 family. (425 aa)
VIPR2Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (530 aa)
THRANuclear receptor domain-containing protein. (312 aa)
ALDH1A1Aldehyde dehydrogenase 1 family member A1; Belongs to the aldehyde dehydrogenase family. (501 aa)
ALDH1A3Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (454 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
ARUncharacterized protein. (392 aa)
AVPR1BVasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (426 aa)
INSRInsulin receptor. (1232 aa)
CALCRLCalcitonin receptor like receptor; Belongs to the G-protein coupled receptor 2 family. (461 aa)
SLC40A1Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (573 aa)
PTH1RParathyroid hormone 1 receptor; Belongs to the G-protein coupled receptor 2 family. (574 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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