STRINGSTRING
TRAF5 TRAF5 DCP1B DCP1B IGF2BP1 IGF2BP1 RBM10 RBM10 SCGB1A1 SCGB1A1 EXOSC3 EXOSC3 DHX36 DHX36 CNOT1 CNOT1 CNOT2 CNOT2 TBRG4 TBRG4 MOV10 MOV10 FASTK FASTK TRIM71 TRIM71 FASTKD1 FASTKD1 MLH1 MLH1 TUT7 TUT7 MEIOC MEIOC MYD88 MYD88 APOBEC1 APOBEC1 LSM1 LSM1 CIRBP CIRBP YTHDF1 YTHDF1 ENSNLEP00000048082 ENSNLEP00000048082 PAN3 PAN3 TAF15 TAF15 YTHDF2 YTHDF2 ALKBH5 ALKBH5 ENSNLEP00000046978 ENSNLEP00000046978 SYNCRIP SYNCRIP KHSRP KHSRP NANOS3 NANOS3 ENSNLEP00000044293 ENSNLEP00000044293 ENSNLEP00000044256 ENSNLEP00000044256 FASTKD3 FASTKD3 ZC3H12A ZC3H12A DCP2 DCP2 TNRC6A TNRC6A PABPC4 PABPC4 YBX1 YBX1 TENT5A TENT5A EXOSC2 EXOSC2 VIM VIM SAMD4A SAMD4A TRAF3IP2 TRAF3IP2 PATL1 PATL1 FMR1 FMR1 CNOT4 CNOT4 LARP4B LARP4B EXOSC5 EXOSC5 NOCT NOCT ZFP36 ZFP36 SAMD4B SAMD4B CNOT11 CNOT11 ANGEL2 ANGEL2 METTL3 METTL3 IGF2BP3 IGF2BP3 AXIN2 AXIN2 ZC3H12D ZC3H12D RC3H1 RC3H1 CALCR CALCR VIP VIP CSDC2 CSDC2 PABPN1L PABPN1L DIS3 DIS3 FUS FUS LARP1 LARP1 CNOT8 CNOT8 ZFP36L2 ZFP36L2 ZC3H14 ZC3H14 RC3H2 RC3H2 PAN2 PAN2 TUT4 TUT4 PLEKHN1 PLEKHN1 TNRC6C TNRC6C PRKCA PRKCA NPM1 NPM1 IKBKE IKBKE PCID2 PCID2 MAPKAPK2 MAPKAPK2 TENT4B TENT4B ZFP36L1 ZFP36L1 RBM24 RBM24 PUM1 PUM1 ENSNLEP00000043962 ENSNLEP00000043962 METTL14 METTL14 HNRNPD HNRNPD TRAF2 TRAF2 SLC11A1 SLC11A1 HNRNPA0 HNRNPA0 PDE12 PDE12 DCP1A DCP1A PRKCD PRKCD FASTKD2 FASTKD2 PCBP4 PCBP4 RBM38 RBM38 IGF2BP2 IGF2BP2 CNOT3 CNOT3 CACNG7 CACNG7 RBM46 RBM46 EXOSC7 EXOSC7 MYEF2 MYEF2 PATL2 PATL2 SERBP1 SERBP1 G1RDL6_NOMLE G1RDL6_NOMLE EXOSC9 EXOSC9 PNPT1 PNPT1 TENT5B TENT5B E2F1 E2F1 CARHSP1 CARHSP1 PAIP1 PAIP1 APEX1 APEX1 NT5C3B NT5C3B AGO3 AGO3 PNLDC1 PNLDC1 THRAP3 THRAP3 ELAVL1 ELAVL1 AGO2 AGO2 MEX3D MEX3D EXOSC8 EXOSC8 RNASEL RNASEL DHX9 DHX9 CNOT6L CNOT6L FASTKD5 FASTKD5 ELAVL4 ELAVL4 POLR2D POLR2D DCPS DCPS BOLL BOLL DAZL DAZL ENSNLEP00000027802 ENSNLEP00000027802 AKT1 AKT1 FXR1 FXR1 GDNF GDNF ENSNLEP00000029090 ENSNLEP00000029090 ENSNLEP00000029300 ENSNLEP00000029300 ENSNLEP00000029492 ENSNLEP00000029492 ENSNLEP00000029616 ENSNLEP00000029616 ENSNLEP00000030705 ENSNLEP00000030705 YBX3 YBX3 PABPC1 PABPC1 CNOT10 CNOT10 RIDA RIDA PUM2 PUM2 PABPC4L PABPC4L ENSNLEP00000034490 ENSNLEP00000034490 DIS3L2 DIS3L2 TNRC6B TNRC6B METTL16 METTL16 ENSNLEP00000035406 ENSNLEP00000035406 YTHDF3 YTHDF3 ROCK2 ROCK2 G1RL24_NOMLE G1RL24_NOMLE ENSNLEP00000036988 ENSNLEP00000036988 ENSNLEP00000037238 ENSNLEP00000037238 FXR2 FXR2 TENT5C TENT5C ENSNLEP00000037399 ENSNLEP00000037399 CSDE1 CSDE1 LOC100584516 LOC100584516 EIF4ENIF1 EIF4ENIF1 ENSNLEP00000039248 ENSNLEP00000039248 ENSNLEP00000039632 ENSNLEP00000039632 DND1 DND1 ENSNLEP00000039968 ENSNLEP00000039968 ENSNLEP00000040325 ENSNLEP00000040325 UPF1 UPF1 FTO FTO HNRNPU HNRNPU CPEB3 CPEB3 ENSNLEP00000043660 ENSNLEP00000043660 ROCK1 ROCK1 TIRAP TIRAP HNRNPM HNRNPM LRRC27 LRRC27 CNOT6 CNOT6 CNOT7 CNOT7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (557 aa)
DCP1BDecapping mRNA 1B. (613 aa)
IGF2BP1Insulin like growth factor 2 mRNA binding protein 1. (577 aa)
RBM10RNA binding motif protein 10. (908 aa)
SCGB1A1Secretoglobin family 1A member 1. (91 aa)
EXOSC3Exosome component 3. (275 aa)
DHX36DEAH-box helicase 36. (1007 aa)
CNOT1CCR4-NOT transcription complex subunit 1. (2375 aa)
CNOT2CCR4-NOT transcription complex subunit 2. (548 aa)
TBRG4Transforming growth factor beta regulator 4. (631 aa)
MOV10Mov10 RISC complex RNA helicase. (976 aa)
FASTKFas activated serine/threonine kinase. (549 aa)
TRIM71Tripartite motif containing 71. (868 aa)
FASTKD1FAST kinase domains 1. (847 aa)
MLH1MutL homolog 1. (756 aa)
TUT7Terminal uridylyl transferase 7. (1493 aa)
MEIOCMeiosis specific with coiled-coil domain. (932 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (317 aa)
APOBEC1Apolipoprotein B mRNA editing enzyme catalytic subunit 1. (236 aa)
LSM1U6 snRNA-associated Sm-like protein LSm1; Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation. (133 aa)
CIRBPRRM domain-containing protein. (147 aa)
YTHDF1Uncharacterized protein. (52 aa)
ENSNLEP00000048082Uncharacterized protein. (546 aa)
PAN3PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (887 aa)
TAF15TATA-box binding protein associated factor 15. (601 aa)
YTHDF2YTH N6-methyladenosine RNA binding protein 2. (595 aa)
ALKBH5AlkB homolog 5, RNA demethylase. (380 aa)
ENSNLEP00000046978Uncharacterized protein. (259 aa)
SYNCRIPSynaptotagmin binding cytoplasmic RNA interacting protein. (638 aa)
KHSRPKH-type splicing regulatory protein. (651 aa)
NANOS3Nanos C2HC-type zinc finger 3; Belongs to the nanos family. (193 aa)
ENSNLEP00000044293Agenet-like domain-containing protein. (471 aa)
ENSNLEP00000044256CSP domain-containing protein. (264 aa)
FASTKD3FAST kinase domains 3. (659 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (560 aa)
DCP2Decapping mRNA 2. (420 aa)
TNRC6ATrinucleotide repeat containing adaptor 6A. (1940 aa)
PABPC4Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (644 aa)
YBX1Y-box binding protein 1. (324 aa)
TENT5ATerminal nucleotidyltransferase 5A. (443 aa)
EXOSC2Exosome component 2. (293 aa)
VIMIF rod domain-containing protein; Belongs to the intermediate filament family. (228 aa)
SAMD4ASAM domain-containing protein. (632 aa)
TRAF3IP2TRAF3 interacting protein 2. (542 aa)
PATL1PAT1 homolog 1, processing body mRNA decay factor. (746 aa)
FMR1Fragile X mental retardation 1. (632 aa)
CNOT4CCR4-NOT transcription complex subunit 4. (712 aa)
LARP4BLa ribonucleoprotein domain family member 4B. (738 aa)
EXOSC5Exosome component 5. (235 aa)
NOCTNocturnin. (368 aa)
ZFP36ZFP36 ring finger protein. (322 aa)
SAMD4BSterile alpha motif domain containing 4B. (679 aa)
CNOT11CCR4-NOT transcription complex subunit 11. (510 aa)
ANGEL2Angel homolog 2. (544 aa)
METTL3Methyltransferase like 3; Belongs to the MT-A70-like family. (580 aa)
IGF2BP3Insulin like growth factor 2 mRNA binding protein 3. (586 aa)
AXIN2DIX domain-containing protein. (294 aa)
ZC3H12DC3H1-type domain-containing protein. (430 aa)
RC3H1Ring finger and CCCH-type domains 1. (1133 aa)
CALCRCalcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (509 aa)
VIPVasoactive intestinal peptide. (170 aa)
CSDC2CSD domain-containing protein. (100 aa)
PABPN1LUncharacterized protein. (186 aa)
DIS3DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (958 aa)
FUSFUS RNA binding protein. (519 aa)
LARP1La ribonucleoprotein domain family member 1. (1007 aa)
CNOT8CCR4-NOT transcription complex subunit 8. (257 aa)
ZFP36L2ZFP36 ring finger protein like 2. (495 aa)
ZC3H14Zinc finger CCCH-type containing 14. (705 aa)
RC3H2Ring finger and CCCH-type domains 2. (1180 aa)
PAN2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1168 aa)
TUT4Terminal uridylyl transferase 4. (1628 aa)
PLEKHN1Pleckstrin homology domain containing N1. (657 aa)
TNRC6CTrinucleotide repeat containing adaptor 6C. (1908 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
NPM1Nucleophosmin 1. (294 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (676 aa)
PCID2PCI domain containing 2. (453 aa)
MAPKAPK2MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (370 aa)
TENT4BTerminal nucleotidyltransferase 4B. (693 aa)
ZFP36L1ZFP36 ring finger protein like 1. (338 aa)
RBM24RNA binding motif protein 24. (197 aa)
PUM1Pumilio RNA binding family member 1. (1224 aa)
ENSNLEP00000043962Uncharacterized protein. (545 aa)
METTL14Methyltransferase like 14; Belongs to the MT-A70-like family. (456 aa)
HNRNPDHeterogeneous nuclear ribonucleoprotein D. (355 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
SLC11A1Solute carrier family 11 member 1. (550 aa)
HNRNPA0Heterogeneous nuclear ribonucleoprotein A0. (311 aa)
PDE12Endo/exonuclease/phosphatase domain-containing protein. (609 aa)
DCP1ADecapping mRNA 1A. (581 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
FASTKD2FAST kinase domains 2. (709 aa)
PCBP4Poly(rC) binding protein 4. (403 aa)
RBM38Uncharacterized protein. (158 aa)
IGF2BP2Insulin like growth factor 2 mRNA binding protein 2. (522 aa)
CNOT3CCR4-NOT transcription complex subunit 3. (726 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (271 aa)
RBM46RNA binding motif protein 46. (486 aa)
EXOSC7Exosome component 7. (291 aa)
MYEF2Myelin expression factor 2. (600 aa)
PATL2PAT1 homolog 2. (538 aa)
SERBP1SERPINE1 mRNA binding protein 1. (358 aa)
G1RDL6_NOMLEUncharacterized protein. (279 aa)
EXOSC9Exosome component 9. (456 aa)
PNPT1Polyribonucleotide nucleotidyltransferase 1. (772 aa)
TENT5BTerminal nucleotidyltransferase 5B. (425 aa)
E2F1E2F transcription factor 1. (391 aa)
CARHSP1Calcium regulated heat stable protein 1. (147 aa)
PAIP1Poly(A) binding protein interacting protein 1. (424 aa)
APEX1DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (318 aa)
NT5C3B5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (300 aa)
AGO3Argonaute RISC catalytic component 3; Belongs to the argonaute family. (845 aa)
PNLDC1PARN like, ribonuclease domain containing 1. (520 aa)
THRAP3Thyroid hormone receptor associated protein 3. (954 aa)
ELAVL1ELAV-like protein; Belongs to the RRM elav family. (326 aa)
AGO2Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (847 aa)
MEX3DRING-type domain-containing protein. (400 aa)
EXOSC8Exosome component 8. (276 aa)
RNASELRibonuclease L. (741 aa)
DHX9DExH-box helicase 9. (1275 aa)
CNOT6LCCR4-NOT transcription complex subunit 6 like. (561 aa)
FASTKD5FAST kinase domains 5. (737 aa)
ELAVL4ELAV-like protein; Belongs to the RRM elav family. (402 aa)
POLR2DRNA polymerase II subunit D. (154 aa)
DCPSDecapping enzyme, scavenger. (337 aa)
BOLLBoule homolog, RNA binding protein. (320 aa)
DAZLDeleted in azoospermia like. (315 aa)
ENSNLEP00000027802Uncharacterized protein. (223 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa)
FXR1FMR1 autosomal homolog 1. (661 aa)
GDNFTGF_BETA_2 domain-containing protein. (169 aa)
ENSNLEP00000029090Uncharacterized protein. (278 aa)
ENSNLEP00000029300RRM domain-containing protein. (480 aa)
ENSNLEP00000029492RRM domain-containing protein. (480 aa)
ENSNLEP00000029616RGS domain-containing protein. (169 aa)
ENSNLEP00000030705Uncharacterized protein. (61 aa)
YBX3Y-box binding protein 3. (344 aa)
PABPC1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (639 aa)
CNOT10CCR4-NOT transcription complex subunit 10. (804 aa)
RIDAReactive intermediate imine deaminase A homolog. (137 aa)
PUM2Pumilio RNA binding family member 2. (1068 aa)
PABPC4LPoly(A) binding protein cytoplasmic 4 like. (370 aa)
ENSNLEP00000034490Uncharacterized protein. (232 aa)
DIS3L2DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] (862 aa)
TNRC6BTrinucleotide repeat containing adaptor 6B. (1727 aa)
METTL16U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...] (589 aa)
ENSNLEP00000035406Uncharacterized protein. (442 aa)
YTHDF3YTH N6-methyladenosine RNA binding protein 3. (587 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa)
G1RL24_NOMLEPAP-associated domain-containing protein. (652 aa)
ENSNLEP00000036988Nucleoplasmin domain-containing protein. (224 aa)
ENSNLEP00000037238Uncharacterized protein. (268 aa)
FXR2FMR1 autosomal homolog 2. (657 aa)
TENT5CTerminal nucleotidyltransferase 5C. (391 aa)
ENSNLEP00000037399S1 motif domain-containing protein. (687 aa)
CSDE1Cold shock domain containing E1. (844 aa)
LOC100584516Uncharacterized protein. (306 aa)
EIF4ENIF1Eukaryotic translation initiation factor 4E nuclear import factor 1. (984 aa)
ENSNLEP00000039248Uncharacterized protein. (542 aa)
ENSNLEP00000039632IHABP4_N domain-containing protein. (150 aa)
DND1DND microRNA-mediated repression inhibitor 1. (353 aa)
ENSNLEP00000039968Nucleoplasmin domain-containing protein. (274 aa)
ENSNLEP00000040325Endo/exonuclease/phosphatase domain-containing protein. (596 aa)
UPF1UPF1 RNA helicase and ATPase. (996 aa)
FTOFTO alpha-ketoglutarate dependent dioxygenase. (559 aa)
HNRNPUB30.2/SPRY domain-containing protein. (725 aa)
CPEB3Cytoplasmic polyadenylation element binding protein 3. (717 aa)
ENSNLEP00000043660CSP domain-containing protein. (328 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1359 aa)
TIRAPTIR domain containing adaptor protein. (221 aa)
HNRNPMHnRNP_M domain-containing protein. (100 aa)
LRRC27Leucine rich repeat containing 27. (518 aa)
CNOT6CCR4-NOT transcription complex subunit 6. (552 aa)
CNOT7CCR4-NOT transcription complex subunit 7. (285 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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