Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABL1 | ATM | ENSNLEP00000015256 | ENSNLEP00000008823 | Tyrosine-protein kinase. | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | 0.974 |
| ABL1 | CASP9 | ENSNLEP00000015256 | ENSNLEP00000009264 | Tyrosine-protein kinase. | Caspase 9; Belongs to the peptidase C14A family. | 0.403 |
| ABL1 | CDK5 | ENSNLEP00000015256 | ENSNLEP00000005013 | Tyrosine-protein kinase. | Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. | 0.731 |
| ABL1 | CTNNB1 | ENSNLEP00000015256 | ENSNLEP00000006991 | Tyrosine-protein kinase. | Catenin beta 1. | 0.838 |
| ABL1 | ENSNLEP00000036861 | ENSNLEP00000015256 | ENSNLEP00000036861 | Tyrosine-protein kinase. | Uncharacterized protein. | 0.731 |
| ABL1 | FBXW7 | ENSNLEP00000015256 | ENSNLEP00000007135 | Tyrosine-protein kinase. | F-box and WD repeat domain containing 7. | 0.531 |
| ABL1 | MCL1 | ENSNLEP00000015256 | ENSNLEP00000012087 | Tyrosine-protein kinase. | MCL1 apoptosis regulator, BCL2 family member. | 0.583 |
| ABL1 | NF1 | ENSNLEP00000015256 | ENSNLEP00000040439 | Tyrosine-protein kinase. | Neurofibromin 1. | 0.400 |
| ABL1 | TNF | ENSNLEP00000015256 | ENSNLEP00000047690 | Tyrosine-protein kinase. | Tumor necrosis factor; Belongs to the tumor necrosis factor family. | 0.408 |
| AIFM1 | BAX | ENSNLEP00000018575 | ENSNLEP00000005703 | Apoptosis inducing factor mitochondria associated 1. | Uncharacterized protein. | 0.915 |
| ATF2 | ATF4 | ENSNLEP00000033876 | ENSNLEP00000018522 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. | BZIP domain-containing protein. | 0.954 |
| ATF2 | DDIT3 | ENSNLEP00000033876 | ENSNLEP00000021003 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] | 0.445 |
| ATF2 | LOC100605818 | ENSNLEP00000033876 | ENSNLEP00000030260 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. | BZIP domain-containing protein. | 0.561 |
| ATF4 | ATF2 | ENSNLEP00000018522 | ENSNLEP00000033876 | BZIP domain-containing protein. | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. | 0.954 |
| ATF4 | DDIT3 | ENSNLEP00000018522 | ENSNLEP00000021003 | BZIP domain-containing protein. | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] | 0.984 |
| ATM | ABL1 | ENSNLEP00000008823 | ENSNLEP00000015256 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Tyrosine-protein kinase. | 0.974 |
| ATM | CASP9 | ENSNLEP00000008823 | ENSNLEP00000009264 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Caspase 9; Belongs to the peptidase C14A family. | 0.400 |
| ATM | CTNNB1 | ENSNLEP00000008823 | ENSNLEP00000006991 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | Catenin beta 1. | 0.498 |
| ATM | FBXW7 | ENSNLEP00000008823 | ENSNLEP00000007135 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | F-box and WD repeat domain containing 7. | 0.571 |
| ATM | MCL1 | ENSNLEP00000008823 | ENSNLEP00000012087 | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | MCL1 apoptosis regulator, BCL2 family member. | 0.404 |
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