39 items (Nomascus leucogenys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

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gene fusions

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textmining

co-expression

protein homology

Your Input:
	SELE	Selectin E. (612 aa)
	TNF	Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
	ENSNLEP00000044718	Uncharacterized protein. (113 aa)
	ROCK1	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1359 aa)
	CX3CR1	C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (386 aa)
	SPN	Sialophorin. (400 aa)
	SELL	L-selectin; Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. (385 aa)
	GCNT1	Glucosaminyl (N-acetyl) transferase 1. (428 aa)
	PRTN3	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (160 aa)
	ADD2	Adducin 2. (726 aa)
	CD177	Uncharacterized protein. (140 aa)
	GOLPH3	Golgi phosphoprotein 3. (298 aa)
	CD99L2	CD99 molecule like 2. (258 aa)
	F11R	F11 receptor. (299 aa)
	ITGB7	Integrin beta; Belongs to the integrin beta chain family. (799 aa)
	ITGAL	Integrin subunit alpha L; Belongs to the integrin alpha chain family. (1142 aa)
	PECAM1	Platelet and endothelial cell adhesion molecule 1. (721 aa)
	SELP	Selectin P. (830 aa)
	PODXL2	Podocalyxin like 2. (598 aa)
	ICAM1	Intercellular adhesion molecule 1. (531 aa)
	VCAM1	Vascular cell adhesion molecule 1. (739 aa)
	FER	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
	ITGA1	Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1179 aa)
	TRIM55	Tripartite motif containing 55. (547 aa)
	PIK3CD	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family. (1077 aa)
	SIRPA	Uncharacterized protein. (486 aa)
	PIK3CG	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa)
	XG	Uncharacterized protein. (147 aa)
	JAML	Junction adhesion molecule like. (394 aa)
	SELPLG	Selectin P ligand. (428 aa)
	ITGA4	Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa)
	EXT1	Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (745 aa)
	CX3CL1	C-X3-C motif chemokine ligand 1. (397 aa)
	ITGB2	Integrin beta. (762 aa)
	JAM2	Junctional adhesion molecule 2. (312 aa)
	G1QJP9_NOMLE	Peptidase S1 domain-containing protein. (178 aa)
	CRK	Uncharacterized protein. (252 aa)
	MADCAM1	Mucosal vascular addressin cell adhesion molecule 1. (398 aa)
	CRKL	CRK like proto-oncogene, adaptor protein. (303 aa)

Your Current Organism:

Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADD2	ROCK1	ENSNLEP00000031313	ENSNLEP00000043861	Adducin 2.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.431
CD177	PECAM1	ENSNLEP00000028097	ENSNLEP00000018277	Uncharacterized protein.	Platelet and endothelial cell adhesion molecule 1.	0.779
CD177	PRTN3	ENSNLEP00000028097	ENSNLEP00000032802	Uncharacterized protein.	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.741
CD99L2	F11R	ENSNLEP00000025380	ENSNLEP00000023319	CD99 molecule like 2.	F11 receptor.	0.471
CD99L2	PECAM1	ENSNLEP00000025380	ENSNLEP00000018277	CD99 molecule like 2.	Platelet and endothelial cell adhesion molecule 1.	0.590
CD99L2	SPN	ENSNLEP00000025380	ENSNLEP00000041749	CD99 molecule like 2.	Sialophorin.	0.540
CRK	CRKL	ENSNLEP00000000851	ENSNLEP00000000117	Uncharacterized protein.	CRK like proto-oncogene, adaptor protein.	0.975
CRK	ITGA1	ENSNLEP00000000851	ENSNLEP00000013222	Uncharacterized protein.	Integrin subunit alpha 1; Belongs to the integrin alpha chain family.	0.715
CRK	ITGA4	ENSNLEP00000000851	ENSNLEP00000007665	Uncharacterized protein.	Integrin subunit alpha 4; Belongs to the integrin alpha chain family.	0.764
CRK	ITGB7	ENSNLEP00000000851	ENSNLEP00000021501	Uncharacterized protein.	Integrin beta; Belongs to the integrin beta chain family.	0.772
CRKL	CRK	ENSNLEP00000000117	ENSNLEP00000000851	CRK like proto-oncogene, adaptor protein.	Uncharacterized protein.	0.975
CRKL	ITGA1	ENSNLEP00000000117	ENSNLEP00000013222	CRK like proto-oncogene, adaptor protein.	Integrin subunit alpha 1; Belongs to the integrin alpha chain family.	0.715
CRKL	ITGA4	ENSNLEP00000000117	ENSNLEP00000007665	CRK like proto-oncogene, adaptor protein.	Integrin subunit alpha 4; Belongs to the integrin alpha chain family.	0.764
CRKL	ITGB7	ENSNLEP00000000117	ENSNLEP00000021501	CRK like proto-oncogene, adaptor protein.	Integrin beta; Belongs to the integrin beta chain family.	0.774
CRKL	PIK3CD	ENSNLEP00000000117	ENSNLEP00000011381	CRK like proto-oncogene, adaptor protein.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family.	0.540
CX3CL1	CX3CR1	ENSNLEP00000003473	ENSNLEP00000042176	C-X3-C motif chemokine ligand 1.	C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.976
CX3CL1	ICAM1	ENSNLEP00000003473	ENSNLEP00000014758	C-X3-C motif chemokine ligand 1.	Intercellular adhesion molecule 1.	0.499
CX3CL1	ITGA4	ENSNLEP00000003473	ENSNLEP00000007665	C-X3-C motif chemokine ligand 1.	Integrin subunit alpha 4; Belongs to the integrin alpha chain family.	0.446
CX3CL1	PECAM1	ENSNLEP00000003473	ENSNLEP00000018277	C-X3-C motif chemokine ligand 1.	Platelet and endothelial cell adhesion molecule 1.	0.513
CX3CL1	SELE	ENSNLEP00000003473	ENSNLEP00000038032	C-X3-C motif chemokine ligand 1.	Selectin E.	0.463

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