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NELL1 NELL1 LOC101176289 LOC101176289 G1SBN8_NOMLE G1SBN8_NOMLE HGF HGF ENSNLEP00000025226 ENSNLEP00000025226 BMPR1A BMPR1A LRP5L LRP5L PDLIM7 PDLIM7 LOC100588616 LOC100588616 YAP1 YAP1 PPP3CA PPP3CA ENSNLEP00000032543 ENSNLEP00000032543 LTF LTF TP63 TP63 MEF2C MEF2C CCN4 CCN4 IL6R IL6R FERMT2 FERMT2 FBN2 FBN2 ATRAID ATRAID BMPR2 BMPR2 CLIC1 CLIC1 SMAD5 SMAD5 IGF1 IGF1 GDPD2 GDPD2 FBXO5 FBXO5 WNT10B WNT10B IL6 IL6 ACVR1 ACVR1 IL6ST IL6ST WWTR1 WWTR1 GLI3 GLI3 CTHRC1 CTHRC1 G1QYG1_NOMLE G1QYG1_NOMLE ACVR2B ACVR2B SMAD1 SMAD1 CTNNB1 CTNNB1 SFRP2 SFRP2 ZHX3 ZHX3 LRP5 LRP5 BMP7 BMP7 LRP3 LRP3 SCUBE3 SCUBE3 ACVR2A ACVR2A CTNNBIP1 CTNNBIP1 WDR63 WDR63 CCN1 CCN1 BMP6 BMP6 TENT5A TENT5A BMP4 BMP4 FFAR4 FFAR4 WNT7B WNT7B BMP2 BMP2 BMPR1B BMPR1B NPPC NPPC JAG1 JAG1 DDR2 DDR2 SUCO SUCO GDF10 GDF10 PRKD1 PRKD1 SCUBE2 SCUBE2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NELL1Neural EGFL like 1. (838 aa)
LOC101176289Uncharacterized protein. (244 aa)
G1SBN8_NOMLEChloride intracellular channel protein; Belongs to the chloride channel CLIC family. (247 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (729 aa)
ENSNLEP00000025226Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (244 aa)
BMPR1ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (533 aa)
LRP5LUncharacterized protein. (150 aa)
PDLIM7Uncharacterized protein. (368 aa)
LOC100588616Runt domain-containing protein. (504 aa)
YAP1Uncharacterized protein. (418 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
ENSNLEP00000032543Uncharacterized protein. (168 aa)
LTFUncharacterized protein. (453 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
CCN4Cellular communication network factor 4. (318 aa)
IL6RInterleukin 6 receptor. (420 aa)
FERMT2Fermitin family member 2. (693 aa)
FBN2Fibrillin 2. (2858 aa)
ATRAIDAll-trans retinoic acid induced differentiation factor. (271 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
CLIC1Uncharacterized protein. (188 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
IGF1IlGF domain-containing protein. (196 aa)
GDPD2Glycerophosphodiester phosphodiesterase domain containing 2. (590 aa)
FBXO5F-box protein 5. (428 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (335 aa)
IL6Uncharacterized protein. (258 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
IL6STInterleukin 6 signal transducer. (918 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
GLI3GLI family zinc finger 3. (1502 aa)
CTHRC1Collagen triple helix repeat containing 1. (242 aa)
G1QYG1_NOMLEProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (323 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (512 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
CTNNB1Catenin beta 1. (781 aa)
SFRP2Secreted frizzled related protein 2. (280 aa)
ZHX3Zinc fingers and homeoboxes 3. (968 aa)
LRP5LDL receptor related protein 5. (1510 aa)
BMP7Bone morphogenetic protein 7. (430 aa)
LRP3LDL receptor related protein 3. (770 aa)
SCUBE3Signal peptide, CUB domain and EGF like domain containing 3. (910 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
CTNNBIP1Catenin beta interacting protein 1. (81 aa)
WDR63WD repeat domain 63. (880 aa)
CCN1Cellular communication network factor 1. (317 aa)
BMP6TGF_BETA_2 domain-containing protein. (125 aa)
TENT5ATerminal nucleotidyltransferase 5A. (443 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
FFAR4G_PROTEIN_RECEP_F1_2 domain-containing protein. (235 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
NPPCNatriuretic peptide C. (129 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1157 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (855 aa)
SUCOSUN domain containing ossification factor. (1373 aa)
GDF10Bone morphogenetic protein 3; Belongs to the TGF-beta family. (477 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (832 aa)
SCUBE2Signal peptide, CUB domain and EGF like domain containing 2. (954 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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