STRINGSTRING
FSHR FSHR PALM PALM RXFP2 RXFP2 ACR ACR CALCA CALCA VIPR2 VIPR2 GALR2 GALR2 CACNA1C CACNA1C HPCA HPCA GPR87 GPR87 P2RY13 P2RY13 EDNRA EDNRA HRH4 HRH4 ADCYAP1 ADCYAP1 GNAI2 GNAI2 GRM2 GRM2 NPFFR2 NPFFR2 LHCGR LHCGR GALR1 GALR1 GNAS GNAS GLP1R GLP1R AVPR2 AVPR2 HPCAL1 HPCAL1 ADGRV1 ADGRV1 NPR3 NPR3 ADORA2B ADORA2B GHRHR GHRHR CALCR CALCR EDNRB EDNRB TSHR TSHR GABBR2 GABBR2 ADRB1 ADRB1 AKAP5 AKAP5 P2RY11 P2RY11 DRD3 DRD3 STIM1 STIM1 DRD2 DRD2 CALM1 CALM1 TMIGD3 TMIGD3 GABBR1 GABBR1 DRD1 DRD1 NF1 NF1 LOC105739044 LOC105739044 CACNA1D CACNA1D
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FSHRFollicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (695 aa)
PALMParalemmin. (369 aa)
RXFP2Relaxin family peptide receptor 2. (750 aa)
ACRAcrosin; Belongs to the peptidase S1 family. (439 aa)
CALCACalcitonin related polypeptide alpha. (141 aa)
VIPR2Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (530 aa)
GALR2Galanin receptor 2; Belongs to the G-protein coupled receptor 1 family. (387 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1985 aa)
HPCAHippocalcin. (193 aa)
GPR87G protein-coupled receptor 87; Belongs to the G-protein coupled receptor 1 family. (358 aa)
P2RY13Purinergic receptor P2Y13; Belongs to the G-protein coupled receptor 1 family. (353 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
HRH4G_PROTEIN_RECEP_F1_2 domain-containing protein. (264 aa)
ADCYAP1Adenylate cyclase activating polypeptide 1. (176 aa)
GNAI2G protein subunit alpha i2. (355 aa)
GRM2Glutamate metabotropic receptor 2. (873 aa)
NPFFR2Neuropeptide FF receptor 2; Belongs to the G-protein coupled receptor 1 family. (487 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (701 aa)
GALR1Galanin receptor 1; Belongs to the G-protein coupled receptor 1 family. (349 aa)
GNASGNAS complex locus. (1038 aa)
GLP1RGlucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (462 aa)
AVPR2Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (371 aa)
HPCAL1Hippocalcin like 1. (193 aa)
ADGRV1Adhesion G protein-coupled receptor V1; Belongs to the G-protein coupled receptor 2 family. (6305 aa)
NPR3Natriuretic peptide receptor 3. (537 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (329 aa)
GHRHRGrowth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (424 aa)
CALCRCalcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (509 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (532 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa)
GABBR2Gamma-aminobutyric acid type B receptor subunit 2. (941 aa)
ADRB1Adrenoceptor beta 1. (476 aa)
AKAP5A-kinase anchoring protein 5. (427 aa)
P2RY11Purinergic receptor P2Y11; Belongs to the G-protein coupled receptor 1 family. (374 aa)
DRD3Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (400 aa)
STIM1Stromal interaction molecule 1. (818 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (445 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (150 aa)
TMIGD3Transmembrane and immunoglobulin domain containing 3; Belongs to the G-protein coupled receptor 1 family. (347 aa)
GABBR1G_PROTEIN_RECEP_F3_4 domain-containing protein. (281 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
NF1Neurofibromin 1. (2839 aa)
LOC105739044Sushi domain-containing protein. (98 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2116 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
Server load: low (20%) [HD]