STRINGSTRING
ANAPC11 ANAPC11 ENSNLEP00000028278 ENSNLEP00000028278 ENSNLEP00000024976 ENSNLEP00000024976 LRP5 LRP5 AURKA AURKA CDC23 CDC23 G1RB97_NOMLE G1RB97_NOMLE INSR INSR EDN1 EDN1 RGCC RGCC IL1A IL1A PRAP1 PRAP1 EGF EGF CD28 CD28 CDT1 CDT1 PDGFB PDGFB FGF8 FGF8 PHIP PHIP ENSNLEP00000024734 ENSNLEP00000024734 PDGFRB PDGFRB SPHK1 SPHK1 ANAPC7 ANAPC7 RB1 RB1 NUSAP1 NUSAP1 CDC27 CDC27 SMPD3 SMPD3 NSMCE2 NSMCE2 TGFA TGFA ESPL1 ESPL1 LRP5L LRP5L IGF2 IGF2 ENSNLEP00000031417 ENSNLEP00000031417 ENSNLEP00000032653 ENSNLEP00000032653 HOXA13 HOXA13 LOC100579835 LOC100579835 EDN3 EDN3 ENSNLEP00000043838 ENSNLEP00000043838 SH2B1 SH2B1 IL1B IL1B IGF1 IGF1 LOC100584037 LOC100584037 DLGAP5 DLGAP5 ENSNLEP00000046587 ENSNLEP00000046587 MAD2L1BP MAD2L1BP EPGN EPGN CUL3 CUL3 ENSNLEP00000026532 ENSNLEP00000026532 CDC16 CDC16 EREG EREG BTC BTC DMRT1 DMRT1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ANAPC11Anaphase promoting complex subunit 11. (194 aa)
ENSNLEP00000028278Uncharacterized protein. (49 aa)
ENSNLEP00000024976Uncharacterized protein. (49 aa)
LRP5LDL receptor related protein 5. (1510 aa)
AURKAAurora kinase A; Belongs to the protein kinase superfamily. (403 aa)
CDC23Cell division cycle 23. (597 aa)
G1RB97_NOMLEUncharacterized protein. (503 aa)
INSRInsulin receptor. (1232 aa)
EDN1Endothelin 1. (211 aa)
RGCCRegulator of cell cycle. (137 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (247 aa)
PRAP1Uncharacterized protein. (152 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1208 aa)
CD28CD28 molecule. (220 aa)
CDT1Chromatin licensing and DNA replication factor 1. (470 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (233 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (221 aa)
PHIPPleckstrin homology domain interacting protein. (1953 aa)
ENSNLEP00000024734Uncharacterized protein. (527 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
SPHK1DAGKc domain-containing protein. (398 aa)
ANAPC7Anaphase promoting complex subunit 7. (599 aa)
RB1RB transcriptional corepressor 1. (919 aa)
NUSAP1Uncharacterized protein. (441 aa)
CDC27Cell division cycle 27. (830 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (655 aa)
NSMCE2NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. (247 aa)
TGFATransforming growth factor alpha. (166 aa)
ESPL1Extra spindle pole bodies like 1, separase. (2122 aa)
LRP5LUncharacterized protein. (150 aa)
IGF2IlGF domain-containing protein. (180 aa)
ENSNLEP00000031417Nsp1_C domain-containing protein. (440 aa)
ENSNLEP00000032653Uncharacterized protein. (87 aa)
HOXA13Homeobox domain-containing protein. (227 aa)
LOC100579835Uncharacterized protein. (337 aa)
EDN3Uncharacterized protein. (211 aa)
ENSNLEP00000043838annotation not available (49 aa)
SH2B1SH2B adaptor protein 1. (756 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa)
IGF1IlGF domain-containing protein. (196 aa)
LOC100584037Uncharacterized protein. (387 aa)
DLGAP5DLG associated protein 5. (815 aa)
ENSNLEP00000046587Uncharacterized protein. (384 aa)
MAD2L1BPMAD2L1 binding protein. (274 aa)
EPGNEpithelial mitogen. (154 aa)
CUL3Cullin 3; Belongs to the cullin family. (744 aa)
ENSNLEP00000026532Uncharacterized protein. (390 aa)
CDC16Cell division cycle 16. (612 aa)
EREGEpiregulin. (169 aa)
BTCBetacellulin. (178 aa)
DMRT1Doublesex and mab-3 related transcription factor 1. (373 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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