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XDH XDH HPRT1 HPRT1 AMPD2 AMPD2 GART GART ATIC ATIC PPAT PPAT AK3 AK3 PFAS PFAS NT5C1A NT5C1A AK9 AK9 NT5E NT5E APRT APRT ADSS1 ADSS1 AK1 AK1 ADK ADK AK2 AK2 ENSNLEP00000029241 ENSNLEP00000029241 AK4-2 AK4-2 ENSNLEP00000029534 ENSNLEP00000029534 AMPD1 AMPD1 ADA ADA NUDT2 NUDT2 PAICS PAICS ADSS2 ADSS2 ENSNLEP00000038989 ENSNLEP00000038989 ADSL ADSL ENSNLEP00000044316 ENSNLEP00000044316 AMPD3 AMPD3 AK4 AK4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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XDHXanthine dehydrogenase. (1271 aa)
HPRT1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (218 aa)
AMPD2AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (879 aa)
GARTTrifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (1010 aa)
ATIC5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. (592 aa)
PPATAmidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (545 aa)
AK3GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (223 aa)
PFASUncharacterized protein. (1108 aa)
NT5C1A5'-nucleotidase, cytosolic IA. (328 aa)
AK9Adenylate kinase 9. (1911 aa)
NT5E5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. (574 aa)
APRTAdenine phosphoribosyltransferase. (180 aa)
ADSS1Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (457 aa)
AK1Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. (210 aa)
ADKAdenosine kinase. (362 aa)
AK2Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis. (239 aa)
ENSNLEP00000029241ADK_lid domain-containing protein; Belongs to the adenylate kinase family. (190 aa)
AK4-2ADK_lid domain-containing protein; Belongs to the adenylate kinase family. (209 aa)
ENSNLEP00000029534AIRC domain-containing protein. (373 aa)
AMPD1AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (780 aa)
ADAAdenosine deaminase. (405 aa)
NUDT2Nudix hydrolase 2. (147 aa)
PAICSAIRC domain-containing protein. (451 aa)
ADSS2Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (458 aa)
ENSNLEP00000038989Uncharacterized protein. (64 aa)
ADSLAdenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (498 aa)
ENSNLEP00000044316Uncharacterized protein; Belongs to the adenylate kinase family. (134 aa)
AMPD3AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (776 aa)
AK4Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. (223 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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