STRINGSTRING
AKT1 AKT1 C1QTNF12 C1QTNF12 IRS2 IRS2 IGF1 IGF1 KLF15 KLF15 ENSNLEP00000043688 ENSNLEP00000043688 NFE2L2 NFE2L2 AKT2 AKT2 CAPN10 CAPN10 CREBL2 CREBL2 SLC1A2 SLC1A2 ARPP19 ARPP19 IRS1 IRS1 LOC100605369 LOC100605369 SORBS1 SORBS1 PTPN11 PTPN11 INSR INSR OPN3 OPN3 OCLN OCLN FGF21 FGF21 CLTCL1 CLTCL1 POU4F2 POU4F2 ADIPOQ ADIPOQ APPL1 APPL1 FGF19 FGF19 TERT TERT ERFE ERFE ITLN1 ITLN1 ITLN2 ITLN2 PTH PTH RNASEL RNASEL PRKCI PRKCI MAPK14 MAPK14 ENSNLEP00000024736 ENSNLEP00000024736 RHOQ RHOQ MEF2A MEF2A ENSNLEP00000027584 ENSNLEP00000027584 OSBPL8 OSBPL8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa)
C1QTNF12C1q domain-containing protein. (213 aa)
IRS2Insulin receptor substrate 2. (1344 aa)
IGF1IlGF domain-containing protein. (196 aa)
KLF15Kruppel like factor 15. (410 aa)
ENSNLEP00000043688Uncharacterized protein. (273 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (607 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (398 aa)
CAPN10Calpain 10; Belongs to the peptidase C2 family. (672 aa)
CREBL2BZIP domain-containing protein. (193 aa)
SLC1A2Amino acid transporter. (580 aa)
ARPP19cAMP regulated phosphoprotein 19; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (131 aa)
IRS1Insulin receptor substrate 1. (1242 aa)
LOC100605369Uncharacterized protein. (571 aa)
SORBS1Uncharacterized protein. (1293 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (590 aa)
INSRInsulin receptor. (1232 aa)
OPN3Opsin 3; Belongs to the G-protein coupled receptor 1 family. (336 aa)
OCLNOccludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (522 aa)
FGF21Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
CLTCL1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1638 aa)
POU4F2POU domain protein. (408 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (244 aa)
APPL1Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (674 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (983 aa)
ERFEErythroferrone. (353 aa)
ITLN1Intelectin 1. (313 aa)
ITLN2Uncharacterized protein. (288 aa)
PTHParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (115 aa)
RNASELRibonuclease L. (741 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa)
MAPK14Mitogen-activated protein kinase. (321 aa)
ENSNLEP00000024736Uncharacterized protein. (489 aa)
RHOQUncharacterized protein. (190 aa)
MEF2AMyocyte enhancer factor 2A. (509 aa)
ENSNLEP00000027584SH2 domain-containing protein. (188 aa)
OSBPL8Oxysterol-binding protein; Belongs to the OSBP family. (873 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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