STRINGSTRING
SRI SRI C1QTNF12 C1QTNF12 PTPN11 PTPN11 C1QTNF1 C1QTNF1 ILDR1 ILDR1 CASR CASR PDX1 PDX1 RPH3AL RPH3AL EDN1 EDN1 SNX4 SNX4 RETN RETN PSMD9 PSMD9 RASL10B RASL10B VSNL1 VSNL1 SOX4 SOX4 TMF1 TMF1 GCG GCG AACS AACS GIP GIP SIRT6 SIRT6 INHBA INHBA UCN UCN PLA2G3 PLA2G3 GHRL GHRL TRH TRH TM7SF3 TM7SF3 MYRIP MYRIP NR1H4 NR1H4 FGB FGB FGA FGA GHRH GHRH NNAT NNAT CYP19A1 CYP19A1 GAL GAL ADCYAP1 ADCYAP1 CREB1 CREB1 C2CD2L C2CD2L GRP GRP BAIAP3 BAIAP3 NKX6-1 NKX6-1 GALR1 GALR1 NR0B2 NR0B2 NLGN2 NLGN2 INHA INHA SPP1 SPP1 SPINK1 SPINK1 ABAT ABAT ECRG4 ECRG4 ISL1 ISL1 NMB NMB UCN3 UCN3 BMP6 BMP6 CFTR CFTR SMAD4 SMAD4 TFR2 TFR2 RAB8B RAB8B FFAR4 FFAR4 RBP4 RBP4 OSBP OSBP RFX6 RFX6 C1QTNF3 C1QTNF3 ACSL4 ACSL4 MPC2 MPC2 PCK2 PCK2 GHRHR GHRHR TCF7L2 TCF7L2 STX4 STX4 DAB2 DAB2 MCU MCU OXCT1 OXCT1 PRKCE PRKCE VDR VDR GLUL GLUL P2RY1 P2RY1 GPR68 GPR68 SELENOT SELENOT PPARD PPARD LRRC8A LRRC8A BLK BLK GPER1 GPER1 ENSNLEP00000024736 ENSNLEP00000024736 TNFSF11 TNFSF11 HFE HFE TACR1 TACR1 PPP3CB PPP3CB ENSNLEP00000027457 ENSNLEP00000027457 GCK GCK ENSNLEP00000027584 ENSNLEP00000027584 CD38 CD38 ENSNLEP00000028440 ENSNLEP00000028440 TUNAR TUNAR DRD2 DRD2 NKX3-1 NKX3-1 CRH CRH LOC100605369 LOC100605369 ENSNLEP00000035372 ENSNLEP00000035372 PLA2G6 PLA2G6 PPARG PPARG TRPM4 TRPM4 GABBR1 GABBR1 ENSNLEP00000037750 ENSNLEP00000037750 TRPM2 TRPM2 BAD BAD ADCY8 ADCY8 AIMP1 AIMP1 C1QTNF6 C1QTNF6 ENSNLEP00000039670 ENSNLEP00000039670 CAPN10 CAPN10 ARHGEF7 ARHGEF7 SLC30A8 SLC30A8 FGG FGG VAMP8 VAMP8 EDN3 EDN3 LOC105739044 LOC105739044 ANO1 ANO1 KISS1 KISS1 ENSNLEP00000043688 ENSNLEP00000043688 GPLD1 GPLD1 HNF1A HNF1A IRS2 IRS2 HIF1A HIF1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SRISorcin. (221 aa)
C1QTNF12C1q domain-containing protein. (213 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (590 aa)
C1QTNF1C1q and TNF related 1. (281 aa)
ILDR1Immunoglobulin like domain containing receptor 1. (505 aa)
CASRCalcium sensing receptor. (1088 aa)
PDX1Pancreatic and duodenal homeobox 1. (283 aa)
RPH3ALRabphilin 3A like (without C2 domains). (314 aa)
EDN1Endothelin 1. (211 aa)
SNX4Sorting nexin 4. (442 aa)
RETNResistin. (108 aa)
PSMD9PDZ domain-containing protein. (222 aa)
RASL10BRAS like family 10 member B. (203 aa)
VSNL1Visinin like 1. (191 aa)
SOX4Transcription factor SOX. (459 aa)
TMF1TATA element modulatory factor 1. (1096 aa)
GCGGlucagon. (180 aa)
AACSAcetoacetyl-CoA synthetase. (672 aa)
GIPGastric inhibitory polypeptide. (153 aa)
SIRT6Deacetylase sirtuin-type domain-containing protein. (215 aa)
INHBAInhibin subunit beta A. (426 aa)
UCNUrocortin. (124 aa)
PLA2G3Phospholipase A2 group III. (509 aa)
GHRLGhrelin and obestatin prepropeptide. (117 aa)
TRHPro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (242 aa)
TM7SF3Transmembrane 7 superfamily member 3. (570 aa)
MYRIPMyosin VIIA and Rab interacting protein. (796 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (486 aa)
FGBFibrinogen beta chain. (491 aa)
FGAFibrinogen alpha chain. (863 aa)
GHRHGrowth hormone releasing hormone. (108 aa)
NNATNeuronatin. (81 aa)
CYP19A1Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. (503 aa)
GALGalanin and GMAP prepropeptide. (123 aa)
ADCYAP1Adenylate cyclase activating polypeptide 1. (176 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
C2CD2LC2CD2 like. (716 aa)
GRPGastrin releasing peptide. (148 aa)
BAIAP3BAI1 associated protein 3. (1094 aa)
NKX6-1NK6 homeobox 1. (368 aa)
GALR1Galanin receptor 1; Belongs to the G-protein coupled receptor 1 family. (349 aa)
NR0B2Nuclear receptor subfamily 0 group B member 2. (257 aa)
NLGN2Neuroligin 2. (768 aa)
INHAInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (366 aa)
SPP1Secreted phosphoprotein 1. (314 aa)
SPINK1Serine peptidase inhibitor, Kazal type 1. (79 aa)
ABAT4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (516 aa)
ECRG4ECRG4 augurin precursor. (148 aa)
ISL1ISL LIM homeobox 1. (349 aa)
NMBUncharacterized protein. (121 aa)
UCN3Urocortin 3. (161 aa)
BMP6TGF_BETA_2 domain-containing protein. (125 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1480 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
TFR2Transferrin receptor 2. (698 aa)
RAB8BRAB8B, member RAS oncogene family. (207 aa)
FFAR4G_PROTEIN_RECEP_F1_2 domain-containing protein. (235 aa)
RBP4Retinol-binding protein; Retinol-binding protein that mediates retinol transport in blood plasma. (201 aa)
OSBPOxysterol-binding protein; Belongs to the OSBP family. (807 aa)
RFX6Regulatory factor X6. (928 aa)
C1QTNF3C1q domain-containing protein. (319 aa)
ACSL4Acyl-CoA synthetase long chain family member 4. (711 aa)
MPC2Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (127 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (575 aa)
GHRHRGrowth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (424 aa)
TCF7L2HMG box domain-containing protein. (534 aa)
STX4Syntaxin 4; Belongs to the syntaxin family. (297 aa)
DAB2DAB adaptor protein 2. (749 aa)
MCUMitochondrial calcium uniporter. (352 aa)
OXCT1Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (476 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
VDRVitamin D receptor. (427 aa)
GLULGlutamine synthetase. (373 aa)
P2RY1Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
GPR68G protein-coupled receptor 68; Belongs to the G-protein coupled receptor 1 family. (375 aa)
SELENOTSelenoprotein T; Belongs to the SelWTH family. Selenoprotein T subfamily. (194 aa)
PPARDPeroxisome proliferator activated receptor delta. (441 aa)
LRRC8ALeucine rich repeat containing 8 VRAC subunit A. (810 aa)
BLKTyrosine-protein kinase. (505 aa)
GPER1G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (377 aa)
ENSNLEP00000024736Uncharacterized protein. (489 aa)
TNFSF11Tumor necrosis factor ligand superfamily member. (317 aa)
HFEHomeostatic iron regulator; Belongs to the MHC class I family. (345 aa)
TACR1Tachykinin receptor 1. (406 aa)
PPP3CBSerine/threonine-protein phosphatase. (408 aa)
ENSNLEP00000027457Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family. (329 aa)
GCKPhosphotransferase. (427 aa)
ENSNLEP00000027584SH2 domain-containing protein. (188 aa)
CD38CD38 molecule. (300 aa)
ENSNLEP00000028440Uncharacterized protein. (95 aa)
TUNARTCL1 upstream neural differentiation-associated RNA. (48 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (445 aa)
NKX3-1NK3 homeobox 1. (230 aa)
CRHCorticotropin releasing hormone. (196 aa)
LOC100605369Uncharacterized protein. (571 aa)
ENSNLEP00000035372TGF_BETA_2 domain-containing protein. (392 aa)
PLA2G6Phospholipase A2 group VI. (805 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
TRPM4Uncharacterized protein. (1010 aa)
GABBR1G_PROTEIN_RECEP_F3_4 domain-containing protein. (281 aa)
ENSNLEP00000037750Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family. (341 aa)
TRPM2LSDAT_euk domain-containing protein. (1224 aa)
BADUncharacterized protein. (82 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1255 aa)
AIMP1Aminoacyl tRNA synthetase complex interacting multifunctional protein 1. (321 aa)
C1QTNF6C1q and TNF related 6. (278 aa)
ENSNLEP00000039670Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family. (334 aa)
CAPN10Calpain 10; Belongs to the peptidase C2 family. (672 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (747 aa)
SLC30A8Solute carrier family 30 member 8. (369 aa)
FGGFibrinogen gamma chain. (463 aa)
VAMP8V-SNARE coiled-coil homology domain-containing protein. (116 aa)
EDN3Uncharacterized protein. (211 aa)
LOC105739044Sushi domain-containing protein. (98 aa)
ANO1Anoctamin. (912 aa)
KISS1KiSS-1 metastasis suppressor. (148 aa)
ENSNLEP00000043688Uncharacterized protein. (273 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (840 aa)
HNF1AUncharacterized protein. (562 aa)
IRS2Insulin receptor substrate 2. (1344 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (850 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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