STRINGSTRING
CITED1 CITED1 ATP6AP2 ATP6AP2 AP3D1 AP3D1 BCL2L11 BCL2L11 GNA11 GNA11 GLI3 GLI3 AP1M1 AP1M1 EDNRA EDNRA USP13 USP13 BLOC1S6 BLOC1S6 SLC24A5 SLC24A5 RAB27A RAB27A HPS4 HPS4 KIT KIT ADAMTSL4 ADAMTSL4 ADAMTS9 ADAMTS9 SLC45A2 SLC45A2 ENPP1 ENPP1 RAB38 RAB38 EDNRB EDNRB DCT DCT CD63 CD63 TYRP1 TYRP1 HPS5 HPS5 BLOC1S3 BLOC1S3 HPS6 HPS6 MREG MREG SOX10 SOX10 LRMDA LRMDA OCA2 OCA2 ENSNLEP00000031324 ENSNLEP00000031324 ADAMTS20 ADAMTS20 BLOC1S5 BLOC1S5 MEF2C MEF2C ENSNLEP00000035464 ENSNLEP00000035464 ZEB2 ZEB2 BCL2 BCL2 RAB32 RAB32 EDN3 EDN3 ANKRD27 ANKRD27 MITF MITF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CITED1Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (219 aa)
ATP6AP2ATPase H+ transporting accessory protein 2. (350 aa)
AP3D1Adaptor related protein complex 3 subunit delta 1. (1146 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (198 aa)
GNA11Uncharacterized protein. (217 aa)
GLI3GLI family zinc finger 3. (1502 aa)
AP1M1AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (435 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
USP13Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (807 aa)
BLOC1S6Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...] (176 aa)
SLC24A5Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (500 aa)
RAB27ARAB27A, member RAS oncogene family. (221 aa)
HPS4HPS4 biogenesis of lysosomal organelles complex 3 subunit 2. (708 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (969 aa)
ADAMTSL4ADAMTS like 4. (1081 aa)
ADAMTS9ADAM metallopeptidase with thrombospondin type 1 motif 9. (1935 aa)
SLC45A2Solute carrier family 45 member 2. (530 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase 1. (827 aa)
RAB38RAB38, member RAS oncogene family. (211 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (532 aa)
DCTDopachrome tautomerase. (552 aa)
CD63Tetraspanin. (238 aa)
TYRP1Tyrosinase related protein 1. (537 aa)
HPS5Hermansky-Pudlak syndrome 5 protein homolog; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. (1140 aa)
BLOC1S3Biogenesis of lysosome-related organelles complex 1 subunit 3; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). Belongs to the BLOC1S3 family. (200 aa)
HPS6Hermansky-Pudlak syndrome 6 protein homolog; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. (775 aa)
MREGMelanoregulin. (214 aa)
SOX10HMG box domain-containing protein. (236 aa)
LRMDALeucine rich melanocyte differentiation associated. (226 aa)
OCA2OCA2 melanosomal transmembrane protein. (832 aa)
ENSNLEP00000031324Uncharacterized protein. (255 aa)
ADAMTS20ADAM metallopeptidase with thrombospondin type 1 motif 20. (1912 aa)
BLOC1S5Biogenesis of lysosome-related organelles complex 1 subunit 5; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). (187 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
ENSNLEP00000035464Uncharacterized protein. (276 aa)
ZEB2Zinc finger E-box binding homeobox 2. (1253 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
RAB32Uncharacterized protein. (225 aa)
EDN3Uncharacterized protein. (211 aa)
ANKRD27Ankyrin repeat domain 27. (1050 aa)
MITFMelanocyte inducing transcription factor. (526 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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