STRINGSTRING
KIF5C KIF5C PICALM PICALM AP3D1 AP3D1 CDK5 CDK5 CTNNB1 CTNNB1 BLOC1S6 BLOC1S6 RAB3A RAB3A RAB27A RAB27A AP3B2 AP3B2 AP3B1 AP3B1 AP3M2 AP3M2 SNCA SNCA AP3M1 AP3M1 KIF5B KIF5B BLOC1S3 BLOC1S3 TMEM230 TMEM230 TOR1A TOR1A SNAPIN SNAPIN LIN7A LIN7A DTNBP1 DTNBP1 DNM2 DNM2 SYNJ1 SYNJ1 ENSNLEP00000031524 ENSNLEP00000031524 SPG11 SPG11 BLOC1S5 BLOC1S5 AP3S1 AP3S1 ENSNLEP00000036861 ENSNLEP00000036861 DNM1 DNM1 TRIM46 TRIM46 SNAP91 SNAP91
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KIF5CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (957 aa)
PICALMPhosphatidylinositol binding clathrin assembly protein. (669 aa)
AP3D1Adaptor related protein complex 3 subunit delta 1. (1146 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (320 aa)
CTNNB1Catenin beta 1. (781 aa)
BLOC1S6Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...] (176 aa)
RAB3ARAB3A, member RAS oncogene family. (186 aa)
RAB27ARAB27A, member RAS oncogene family. (221 aa)
AP3B2AP-3 complex subunit beta. (1027 aa)
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1045 aa)
AP3M2AP-3 complex subunit mu-2. (418 aa)
SNCAAlpha-synuclein; Belongs to the synuclein family. (140 aa)
AP3M1AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family. (418 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (963 aa)
BLOC1S3Biogenesis of lysosome-related organelles complex 1 subunit 3; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). Belongs to the BLOC1S3 family. (200 aa)
TMEM230Uncharacterized protein. (127 aa)
TOR1ATorsin. (332 aa)
SNAPINSNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa)
LIN7AProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (233 aa)
DTNBP1Dystrobrevin binding protein 1. (350 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (770 aa)
SYNJ1Synaptojanin 1. (1383 aa)
ENSNLEP00000031524Uncharacterized protein. (55 aa)
SPG11SPG11 vesicle trafficking associated, spatacsin. (2443 aa)
BLOC1S5Biogenesis of lysosome-related organelles complex 1 subunit 5; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). (187 aa)
AP3S1Adaptor related protein complex 3 subunit sigma 1. (193 aa)
ENSNLEP00000036861Uncharacterized protein. (119 aa)
DNM1Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (827 aa)
TRIM46Tripartite motif containing 46. (746 aa)
SNAP91Synaptosome associated protein 91. (907 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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