STRINGSTRING
EIF4A3 EIF4A3 NODAL NODAL TGFB3 TGFB3 TBX15 TBX15 SIX2 SIX2 SETD2 SETD2 FGFR2 FGFR2 WDR19 WDR19 LOC101176289 LOC101176289 SMAD2 SMAD2 CHST11 CHST11 NIPBL NIPBL DLX2 DLX2 LOC100588616 LOC100588616 MMP16 MMP16 ENSNLEP00000034753 ENSNLEP00000034753 SLC39A1 SLC39A1 TGFBR1 TGFBR1 SMAD3 SMAD3 MED12 MED12 ENSNLEP00000044942 ENSNLEP00000044942 RDH10 RDH10 PAX5 PAX5 ALX3 ALX3 GRHL2 GRHL2 GLI3 GLI3 TULP3 TULP3 LHX1 LHX1 IRX5 IRX5 TFAP2A TFAP2A WNT9B WNT9B IFT140 IFT140 NDST1 NDST1 BMP4 BMP4 SIX1 SIX1 MMP14 MMP14 FGF8 FGF8 TGFBR2 TGFBR2 HOXA1 HOXA1 HOXA2 HOXA2 PRRX1 PRRX1 MTHFD1L MTHFD1L
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EIF4A3Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. (411 aa)
NODALNodal growth differentiation factor. (347 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
TBX15T-box transcription factor 15. (579 aa)
SIX2SIX homeobox 2. (293 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2498 aa)
FGFR2Fibroblast growth factor receptor. (820 aa)
WDR19WD repeat domain 19. (1339 aa)
LOC101176289Uncharacterized protein. (244 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
CHST11Carbohydrate sulfotransferase. (352 aa)
NIPBLNipped-B protein. (2803 aa)
DLX2Distal-less homeobox 2. (322 aa)
LOC100588616Runt domain-containing protein. (504 aa)
MMP16Matrix metallopeptidase 16. (607 aa)
ENSNLEP00000034753Uncharacterized protein. (428 aa)
SLC39A1Solute carrier family 39 member 1. (324 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (498 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
MED12Mediator complex subunit 12. (2109 aa)
ENSNLEP00000044942THF_DHG_CYH domain-containing protein. (111 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
PAX5Paired box 5. (391 aa)
ALX3ALX homeobox 3. (346 aa)
GRHL2Grainyhead like transcription factor 2. (625 aa)
GLI3GLI family zinc finger 3. (1502 aa)
TULP3TUB like protein 3; Belongs to the TUB family. (463 aa)
LHX1LIM homeobox 1. (352 aa)
IRX5Iroquois homeobox 5. (483 aa)
TFAP2ATranscription factor AP-2 alpha. (417 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
IFT140Intraflagellar transport 140. (1454 aa)
NDST1N-deacetylase and N-sulfotransferase 1. (880 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
SIX1SIX homeobox 1. (284 aa)
MMP14Matrix metallopeptidase 14. (586 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (221 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
HOXA1Homeobox A1. (314 aa)
HOXA2Homeobox A2. (376 aa)
PRRX1Paired related homeobox 1. (245 aa)
MTHFD1LMethylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (950 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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