STRINGSTRING
SOX9 SOX9 MPV17 MPV17 ENSNLEP00000027584 ENSNLEP00000027584 SPRY2 SPRY2 DLL1 DLL1 LIN7A LIN7A PHOX2B PHOX2B ENSNLEP00000028495 ENSNLEP00000028495 IFT20 IFT20 FGF10 FGF10 CDH23 CDH23 SLC4A7 SLC4A7 HPN HPN MYO6 MYO6 HOXA13 HOXA13 IFT27 IFT27 GRHL3 GRHL3 C1QTNF5 C1QTNF5 BLOC1S5 BLOC1S5 CHD7 CHD7 ENSNLEP00000034753 ENSNLEP00000034753 LOC100605369 LOC100605369 TIFAB TIFAB GABRA5 GABRA5 MCOLN3 MCOLN3 RPGRIP1L RPGRIP1L GJB6 GJB6 TCAP TCAP MKS1 MKS1 TTC8 TTC8 ATP8B1 ATP8B1 ENSNLEP00000041886 ENSNLEP00000041886 HMX2 HMX2 EPHB2 EPHB2 DVL1 DVL1 EPHA4 EPHA4 TBX3 TBX3 DVL2 DVL2 MYO15B MYO15B PCDH15 PCDH15 ENSNLEP00000043688 ENSNLEP00000043688 FZD2 FZD2 EYA1 EYA1 LRRC1 LRRC1 LGR5 LGR5 BCR BCR ENSNLEP00000047564 ENSNLEP00000047564 TSKU TSKU NEUROD1 NEUROD1 ENSNLEP00000047852 ENSNLEP00000047852 CYS1 CYS1 HMX3 HMX3 SLC26A5 SLC26A5 PTPN11 PTPN11 TBX2 TBX2 TFAP2A TFAP2A USH1G USH1G MAPKAPK2 MAPKAPK2 ALDH1A3 ALDH1A3 TMC1 TMC1 IFT88 IFT88 G1QMV4_NOMLE G1QMV4_NOMLE SCRIB SCRIB ZIC1 ZIC1 FREM2 FREM2 HPCA HPCA GLI3 GLI3 CLRN1 CLRN1 SOD1 SOD1 FZD6 FZD6 CTHRC1 CTHRC1 CCM2 CCM2 PTK7 PTK7 GABRB2 GABRB2 OTOL1 OTOL1 PLS1 PLS1 FOXI1 FOXI1 MYO3B MYO3B PTPRQ PTPRQ CEP290 CEP290 DUOX2 DUOX2 SLC17A8 SLC17A8 PJVK PJVK TMIE TMIE FRZB FRZB SLC44A4 SLC44A4 MAFB MAFB TTC39C TTC39C SDC4 SDC4 WNT5A WNT5A HESX1 HESX1 LRIG1 LRIG1 ATG4B ATG4B CECR2 CECR2 PDGFA PDGFA CXCL14 CXCL14 C1QB C1QB NOTCH1 NOTCH1 REST REST LHX3 LHX3 G1RCQ7_NOMLE G1RCQ7_NOMLE TPRN TPRN CCNA2 CCNA2 GRXCR2 GRXCR2 WDPCP WDPCP ATP6V1B1 ATP6V1B1 PDGFRB PDGFRB MAF MAF SLC9A3R1 SLC9A3R1 INSIG1 INSIG1 GBX2 GBX2 PLPPR4 PLPPR4 NAGLU NAGLU STOX1 STOX1 INSIG2 INSIG2 GATA3 GATA3 COL11A1 COL11A1 G1RNL4_NOMLE G1RNL4_NOMLE ITGA8 ITGA8 BMP4 BMP4 TBX18 TBX18 ATG5 ATG5 FGF9 FGF9 SOBP SOBP TGFB1 TGFB1 SIX1 SIX1 HPCAL1 HPCAL1 ADGRV1 ADGRV1 MYO15A MYO15A ATP8A2 ATP8A2 HEY2 HEY2 BMP2 BMP2 MCM2 MCM2 TGFB2 TGFB2 USH2A USH2A GATA2 GATA2 KCNK2 KCNK2 PROX1 PROX1 JAG1 JAG1 EYA4 EYA4 PVALB PVALB AHI1 AHI1 LRP10 LRP10 PAX2 PAX2 PDZD7 PDZD7 GSDME GSDME FGF8 FGF8 HOXA1 HOXA1 ROR1 ROR1 PRRX1 PRRX1 BMPER BMPER NOX3 NOX3 DLX5 DLX5 CYTL1 CYTL1 OTOP1 OTOP1 JAG2 JAG2 SLITRK6 SLITRK6 TGFB3 TGFB3 CLRN2 CLRN2 ESRRB ESRRB SEC24B SEC24B FZD3 FZD3 ALG10 ALG10 MYO7A MYO7A MYO3A MYO3A WHRN WHRN TSHR TSHR FGFR2 FGFR2 ANP32B ANP32B TRIP11 TRIP11 CHRNA9 CHRNA9 LRIG3 LRIG3 CHRNA10 CHRNA10 GRXCR1 GRXCR1 DCHS1 DCHS1 USH1C USH1C WNT1 WNT1 COL2A1 COL2A1 ZEB1 ZEB1 NEUROG1 NEUROG1 ATOH1 ATOH1 SOX2 SOX2 KCNK3 KCNK3 LOC100591198 LOC100591198 CDKN1B CDKN1B ENSNLEP00000024736 ENSNLEP00000024736 LRRC51 LRRC51 FGF20 FGF20 ADAM10 ADAM10 WNT3A WNT3A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SOX9SRY-box transcription factor 9. (510 aa)
MPV17Mitochondrial inner membrane protein MPV17; Belongs to the peroxisomal membrane protein PXMP2/4 family. (191 aa)
ENSNLEP00000027584SH2 domain-containing protein. (188 aa)
SPRY2Sprouty RTK signaling antagonist 2. (338 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (737 aa)
LIN7AProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (233 aa)
PHOX2BPaired like homeobox 2B. (314 aa)
ENSNLEP00000028495Uncharacterized protein. (253 aa)
IFT20Uncharacterized protein. (148 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
CDH23Cadherin related 23. (3327 aa)
SLC4A7Anion exchange protein. (1259 aa)
HPNHepsin; Belongs to the peptidase S1 family. (431 aa)
MYO6Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1294 aa)
HOXA13Homeobox domain-containing protein. (227 aa)
IFT27Intraflagellar transport 27. (186 aa)
GRHL3Grainyhead like transcription factor 3. (597 aa)
C1QTNF5C1q domain-containing protein. (236 aa)
BLOC1S5Biogenesis of lysosome-related organelles complex 1 subunit 5; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). (187 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2997 aa)
ENSNLEP00000034753Uncharacterized protein. (428 aa)
LOC100605369Uncharacterized protein. (571 aa)
TIFABTIFA inhibitor. (162 aa)
GABRA5Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
MCOLN3Mucolipin 3. (553 aa)
RPGRIP1LRPGRIP1 like. (1269 aa)
GJB6Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (261 aa)
TCAPTitin-cap. (167 aa)
MKS1MKS transition zone complex subunit 1. (546 aa)
TTC8Tetratricopeptide repeat domain 8. (515 aa)
ATP8B1Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1251 aa)
ENSNLEP00000041886Ion_trans domain-containing protein; Belongs to the potassium channel family. (359 aa)
HMX2H6 family homeobox 2. (262 aa)
EPHB2EPH receptor B2. (1015 aa)
DVL1Dishevelled segment polarity protein 1. (667 aa)
EPHA4EPH receptor A4. (967 aa)
TBX3T-box transcription factor 3. (743 aa)
DVL2Dishevelled segment polarity protein 2. (713 aa)
MYO15BUncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2609 aa)
PCDH15Protocadherin related 15. (1871 aa)
ENSNLEP00000043688Uncharacterized protein. (273 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (543 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa)
LRRC1Leucine rich repeat containing 1. (503 aa)
LGR5Leucine rich repeat containing G protein-coupled receptor 5. (907 aa)
BCRBCR activator of RhoGEF and GTPase. (1271 aa)
ENSNLEP00000047564Uncharacterized protein. (204 aa)
TSKUTsukushi, small leucine rich proteoglycan. (354 aa)
NEUROD1Neurogenic differentiation factor. (356 aa)
ENSNLEP00000047852Laminin N-terminal domain-containing protein. (447 aa)
CYS1Uncharacterized protein. (121 aa)
HMX3H6 family homeobox 3. (357 aa)
SLC26A5Prestin; Motor protein that converts auditory stimuli to length changes in outer hair cells and mediates sound amplification in the mammalian hearing organ; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (741 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (590 aa)
TBX2T-box transcription factor 2. (647 aa)
TFAP2ATranscription factor AP-2 alpha. (417 aa)
USH1GUSH1 protein network component sans. (452 aa)
MAPKAPK2MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (370 aa)
ALDH1A3Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (454 aa)
TMC1Transmembrane channel-like protein. (747 aa)
IFT88Intraflagellar transport 88. (832 aa)
G1QMV4_NOMLEPhoLip_ATPase_N domain-containing protein. (572 aa)
SCRIBScribble planar cell polarity protein. (1449 aa)
ZIC1Zic family member 1. (451 aa)
FREM2FRAS1 related extracellular matrix 2. (3170 aa)
HPCAHippocalcin. (193 aa)
GLI3GLI family zinc finger 3. (1502 aa)
CLRN1Clarin 1. (245 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa)
CTHRC1Collagen triple helix repeat containing 1. (242 aa)
CCM2CCM2 scaffold protein. (466 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1078 aa)
GABRB2Gamma-aminobutyric acid type A receptor beta2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (512 aa)
OTOL1Otolin 1. (470 aa)
PLS1Plastin 1. (629 aa)
FOXI1Forkhead box I1. (378 aa)
MYO3BMyosin IIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1341 aa)
PTPRQProtein tyrosine phosphatase receptor type Q. (2145 aa)
CEP290Centrosomal protein 290. (2446 aa)
DUOX2Dual oxidase 2. (1548 aa)
SLC17A8Solute carrier family 17 member 8. (589 aa)
PJVKPejvakin. (352 aa)
TMIEUncharacterized protein. (128 aa)
FRZBFrizzled related protein. (325 aa)
SLC44A4Solute carrier family 44 member 4; Belongs to the CTL (choline transporter-like) family. (639 aa)
MAFBMAF bZIP transcription factor B. (323 aa)
TTC39CTetratricopeptide repeat domain 39C. (564 aa)
SDC4Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (198 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
HESX1HESX homeobox 1. (185 aa)
LRIG1Leucine rich repeats and immunoglobulin like domains 1. (1089 aa)
ATG4BCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (398 aa)
CECR2CECR2 histone acetyl-lysine reader. (1441 aa)
PDGFAPlatelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa)
CXCL14C-X-C motif chemokine ligand 14. (111 aa)
C1QBComplement C1q B chain. (253 aa)
NOTCH1Notch receptor 1. (2451 aa)
RESTRE1 silencing transcription factor. (1097 aa)
LHX3Uncharacterized protein. (367 aa)
G1RCQ7_NOMLEUncharacterized protein. (237 aa)
TPRNPhostensin domain-containing protein. (486 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (431 aa)
GRXCR2Glutaredoxin and cysteine rich domain containing 2. (248 aa)
WDPCPWD repeat containing planar cell polarity effector. (746 aa)
ATP6V1B1ATPase H+ transporting V1 subunit B1. (483 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
MAFMAF bZIP transcription factor; Belongs to the bZIP family. (401 aa)
SLC9A3R1Uncharacterized protein. (276 aa)
INSIG1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (274 aa)
GBX2Gastrulation brain homeobox 2. (348 aa)
PLPPR4Phospholipid phosphatase related 4. (689 aa)
NAGLUN-acetyl-alpha-glucosaminidase. (713 aa)
STOX1Storkhead box 1. (937 aa)
INSIG2Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (225 aa)
GATA3GATA binding protein 3. (444 aa)
COL11A1Collagen type XI alpha 1 chain. (1800 aa)
G1RNL4_NOMLEUncharacterized protein. (584 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1048 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
TBX18T-box transcription factor 18. (607 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
SOBPSine oculis binding protein homolog. (873 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
SIX1SIX homeobox 1. (284 aa)
HPCAL1Hippocalcin like 1. (193 aa)
ADGRV1Adhesion G protein-coupled receptor V1; Belongs to the G-protein coupled receptor 2 family. (6305 aa)
MYO15AMyosin XVA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (3516 aa)
ATP8A2Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1161 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
MCM2DNA helicase; Belongs to the MCM family. (786 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
USH2AUsherin. (5203 aa)
GATA2GATA binding protein 2. (480 aa)
KCNK2Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (426 aa)
PROX1Prospero homeobox 1. (737 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1157 aa)
EYA4Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (645 aa)
PVALBParvalbumin; Belongs to the parvalbumin family. (110 aa)
AHI1Abelson helper integration site 1. (1195 aa)
LRP10LDL receptor related protein 10. (713 aa)
PAX2Paired domain-containing protein. (385 aa)
PDZD7PDZ domain containing 7. (1052 aa)
GSDMEGasdermin E. (496 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (221 aa)
HOXA1Homeobox A1. (314 aa)
ROR1Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (937 aa)
PRRX1Paired related homeobox 1. (245 aa)
BMPERBMP binding endothelial regulator. (685 aa)
NOX3NADPH oxidase 3. (568 aa)
DLX5Homeobox domain-containing protein. (191 aa)
CYTL1Cytokine like 1. (136 aa)
OTOP1Otopetrin 1. (612 aa)
JAG2Jagged canonical Notch ligand 2. (1238 aa)
SLITRK6SLIT and NTRK like family member 6. (841 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
CLRN2Clarin 2. (232 aa)
ESRRBUncharacterized protein. (398 aa)
SEC24BSEC24 homolog B, COPII coat complex component. (1236 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
ALG10Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase. (473 aa)
MYO7AMyosin VIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2083 aa)
MYO3AMyosin IIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1609 aa)
WHRNWhirlin. (819 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa)
FGFR2Fibroblast growth factor receptor. (820 aa)
ANP32BAcidic nuclear phosphoprotein 32 family member B. (251 aa)
TRIP11Thyroid hormone receptor interactor 11. (1964 aa)
CHRNA9Cholinergic receptor nicotinic alpha 9 subunit. (479 aa)
LRIG3Leucine rich repeats and immunoglobulin like domains 3. (1119 aa)
CHRNA10Cholinergic receptor nicotinic alpha 10 subunit. (450 aa)
GRXCR1Glutaredoxin and cysteine rich domain containing 1. (290 aa)
DCHS1Dachsous cadherin-related 1. (3297 aa)
USH1CUSH1 protein network component harmonin. (877 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
COL2A1Collagen type II alpha 1 chain. (1487 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1105 aa)
NEUROG1Neurogenin 1. (237 aa)
ATOH1Atonal bHLH transcription factor 1. (354 aa)
SOX2SRY-box transcription factor 2. (319 aa)
KCNK3Ion_trans_2 domain-containing protein. (271 aa)
LOC100591198Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase. (473 aa)
CDKN1BUncharacterized protein. (204 aa)
ENSNLEP00000024736Uncharacterized protein. (489 aa)
LRRC51Uncharacterized protein. (291 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
ADAM10ADAM metallopeptidase domain 10. (748 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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