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ACAD9 ACAD9 PPOX PPOX DUS1L DUS1L NOX5 NOX5 GCDH GCDH DDO DDO MICAL1 MICAL1 ACAD8 ACAD8 ERO1A ERO1A GSR GSR ACOX3 ACOX3 MTRR MTRR PRODH2 PRODH2 AIFM2 AIFM2 ACADM ACADM NDOR1 NDOR1 GFER GFER DUS4L DUS4L POR POR ETFA ETFA ACADVL ACADVL MICAL3 MICAL3 D2HGDH D2HGDH ACOX2 ACOX2 CHDH CHDH ACADL ACADL DAO DAO CRY1 CRY1 TXNRD1 TXNRD1 AGPS AGPS SQOR SQOR TXNRD2 TXNRD2 SQLE SQLE ILVBL ILVBL DUS2 DUS2 PYROXD1 PYROXD1 NOS3 NOS3 ACAD11 ACAD11 PIPOX PIPOX IVD IVD ACOXL ACOXL NOS2 NOS2 KDM1B KDM1B TXNRD3 TXNRD3 CYBB CYBB G1QIA8_NOMLE G1QIA8_NOMLE NOS1 NOS1 FMO5 FMO5 AIFM3 AIFM3 MTHFR MTHFR DLD DLD CYB5R1 CYB5R1 LDHD LDHD ENSNLEP00000043152 ENSNLEP00000043152 XDH XDH ENSNLEP00000040253 ENSNLEP00000040253 SMIM24 SMIM24 PRODH PRODH PCYOX1 PCYOX1 LOC100583419 LOC100583419 ACADSB ACADSB MTO1 MTO1 ACOX1 ACOX1 KDM1A KDM1A AOX1 AOX1 ENSNLEP00000026036 ENSNLEP00000026036 KMO KMO ERO1B ERO1B CRY2 CRY2 MICALCL MICALCL MICAL2 MICAL2 CYB5R2 CYB5R2 COQ6 COQ6 ACADS ACADS AIFM1 AIFM1 FMO4 FMO4 FMO1 FMO1 FMO2 FMO2 FMO3 FMO3 LOC100605282 LOC100605282 STEAP4 STEAP4 DHCR24 DHCR24 FOXRED2 FOXRED2 MMACHC MMACHC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACAD9Acyl-CoA dehydrogenase family member 9. (621 aa)
PPOXProtoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (475 aa)
DUS1LDihydrouridine synthase 1 like. (440 aa)
NOX5NADPH oxidase 5. (763 aa)
GCDHGlutaryl-CoA dehydrogenase. (438 aa)
DDOD-aspartate oxidase. (369 aa)
MICAL1Microtubule associated monooxygenase, calponin and LIM domain containing 1. (1086 aa)
ACAD8Acyl-CoA dehydrogenase family member 8. (415 aa)
ERO1AEndoplasmic reticulum oxidoreductase 1 alpha. (468 aa)
GSRGlutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (522 aa)
ACOX3Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (690 aa)
MTRR5-methyltetrahydrofolate-homocysteine methyltransferase reductase. (698 aa)
PRODH2Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (536 aa)
AIFM2Apoptosis inducing factor mitochondria associated 2. (306 aa)
ACADMAcyl-CoA dehydrogenase medium chain. (454 aa)
NDOR1NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe/S cluster of CIAPIN1. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (595 aa)
GFERSulfhydryl oxidase. (205 aa)
DUS4LtRNA-dihydrouridine synthase; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs; Belongs to the dus family. (317 aa)
PORNADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (680 aa)
ETFAElectron transfer flavoprotein subunit alpha. (333 aa)
ACADVLAcyl-CoA dehydrogenase very long chain. (648 aa)
MICAL3Microtubule associated monooxygenase, calponin and LIM domain containing 3. (2002 aa)
D2HGDHD-2-hydroxyglutarate dehydrogenase. (475 aa)
ACOX2Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (681 aa)
CHDHCholine dehydrogenase. (594 aa)
ACADLAcyl-CoA dehydrogenase long chain. (430 aa)
DAOD-amino acid oxidase. (314 aa)
CRY1Cryptochrome circadian regulator 1. (586 aa)
TXNRD1Thioredoxin reductase 1. (647 aa)
AGPSAlkylglycerone-phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids; Belongs to the FAD-binding oxidoreductase/transferase type 4 family. (656 aa)
SQORUncharacterized protein. (441 aa)
TXNRD2Thioredoxin reductase 2. (522 aa)
SQLESqualene epoxidase. (574 aa)
ILVBLIlvB acetolactate synthase like; Belongs to the TPP enzyme family. (601 aa)
DUS2Dihydrouridine synthase 2. (490 aa)
PYROXD1Pyridine nucleotide-disulphide oxidoreductase domain 1. (500 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1128 aa)
ACAD11Acyl-CoA dehydrogenase family member 11. (781 aa)
PIPOXPipecolic acid and sarcosine oxidase. (390 aa)
IVDIsovaleryl-CoA dehydrogenase. (401 aa)
ACOXLAcyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (580 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1153 aa)
KDM1BUncharacterized protein. (822 aa)
TXNRD3Thioredoxin reductase 3. (561 aa)
CYBBCytochrome b-245 beta chain. (570 aa)
G1QIA8_NOMLEAPH domain-containing protein. (686 aa)
NOS1Nitric oxide synthase; Produces nitric oxide (NO). (1425 aa)
FMO5Dimethylaniline monooxygenase [N-oxide-forming]. (533 aa)
AIFM3Apoptosis inducing factor mitochondria associated 3. (605 aa)
MTHFRMethylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (654 aa)
DLDDihydrolipoyl dehydrogenase. (515 aa)
CYB5R1NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (305 aa)
LDHDFAD-binding PCMH-type domain-containing protein. (539 aa)
ENSNLEP00000043152Uncharacterized protein. (148 aa)
XDHXanthine dehydrogenase. (1271 aa)
ENSNLEP00000040253APH domain-containing protein. (175 aa)
SMIM24Uncharacterized protein. (107 aa)
PRODHProline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (595 aa)
PCYOX1Prenylcysteine oxidase 1. (505 aa)
LOC100583419FAD-binding PCMH-type domain-containing protein. (1085 aa)
ACADSBAcyl-CoA dehydrogenase short/branched chain. (432 aa)
MTO1Mitochondrial tRNA translation optimization 1. (711 aa)
ACOX1Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (661 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (759 aa)
AOX1Aldehyde oxidase 1. (1338 aa)
ENSNLEP00000026036Uncharacterized protein. (315 aa)
KMOKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. (486 aa)
ERO1BEndoplasmic reticulum oxidoreductase 1 beta. (467 aa)
CRY2Photolyase/cryptochrome alpha/beta domain-containing protein. (523 aa)
MICALCLBMERB domain-containing protein. (420 aa)
MICAL2Microtubule associated monooxygenase, calponin and LIM domain containing 2. (1124 aa)
CYB5R2NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (276 aa)
COQ6Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (468 aa)
ACADSAcyl-CoA dehydrogenase short chain. (412 aa)
AIFM1Apoptosis inducing factor mitochondria associated 1. (613 aa)
FMO4Dimethylaniline monooxygenase [N-oxide-forming]. (558 aa)
FMO1Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa)
FMO2Dimethylaniline monooxygenase [N-oxide-forming]. (535 aa)
FMO3Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa)
LOC100605282Dimethylaniline monooxygenase [N-oxide-forming]. (487 aa)
STEAP4STEAP4 metalloreductase. (459 aa)
DHCR2424-dehydrocholesterol reductase. (514 aa)
FOXRED2FAD dependent oxidoreductase domain containing 2. (683 aa)
MMACHCMetabolism of cobalamin associated C. (281 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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