(16 nodes) Progesterone receptor signaling pathway network (Nomascus leucogenys)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	ENSNLEP00000030944	Prohibitin. (220 aa)
	SRC	Tyrosine-protein kinase. (537 aa)
	UBE3A	Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (881 aa)
	ENSNLEP00000046375	Prohibitin. (169 aa)
	ENSNLEP00000042917	Prohibitin. (131 aa)
	ENSNLEP00000037203	Prohibitin. (260 aa)
	ENSNLEP00000035153	Prohibitin. (261 aa)
	WBP2	WW domain binding protein 2. (260 aa)
	ENSNLEP00000032543	Uncharacterized protein. (168 aa)
	PHB	Prohibitin. (272 aa)
	UBR5	Ubiquitin protein ligase E3 component n-recognin 5. (2778 aa)
	TRERF1	Transcriptional regulating factor 1. (1218 aa)
	YAP1	Uncharacterized protein. (418 aa)
	NEDD4	NEDD4 E3 ubiquitin protein ligase. (1319 aa)
	PGR	Uncharacterized protein. (339 aa)
	ENSNLEP00000025813	Prohibitin. (188 aa)

Your Current Organism:

Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSNLEP00000032543	SRC	ENSNLEP00000032543	ENSNLEP00000048569	Uncharacterized protein.	Tyrosine-protein kinase.	0.772
ENSNLEP00000032543	WBP2	ENSNLEP00000032543	ENSNLEP00000033794	Uncharacterized protein.	WW domain binding protein 2.	0.583
NEDD4	WBP2	ENSNLEP00000008096	ENSNLEP00000033794	NEDD4 E3 ubiquitin protein ligase.	WW domain binding protein 2.	0.539
PGR	SRC	ENSNLEP00000008712	ENSNLEP00000048569	Uncharacterized protein.	Tyrosine-protein kinase.	0.813
SRC	ENSNLEP00000032543	ENSNLEP00000048569	ENSNLEP00000032543	Tyrosine-protein kinase.	Uncharacterized protein.	0.772
SRC	PGR	ENSNLEP00000048569	ENSNLEP00000008712	Tyrosine-protein kinase.	Uncharacterized protein.	0.813
SRC	YAP1	ENSNLEP00000048569	ENSNLEP00000031727	Tyrosine-protein kinase.	Uncharacterized protein.	0.772
WBP2	ENSNLEP00000032543	ENSNLEP00000033794	ENSNLEP00000032543	WW domain binding protein 2.	Uncharacterized protein.	0.583
WBP2	NEDD4	ENSNLEP00000033794	ENSNLEP00000008096	WW domain binding protein 2.	NEDD4 E3 ubiquitin protein ligase.	0.539
WBP2	YAP1	ENSNLEP00000033794	ENSNLEP00000031727	WW domain binding protein 2.	Uncharacterized protein.	0.583
YAP1	SRC	ENSNLEP00000031727	ENSNLEP00000048569	Uncharacterized protein.	Tyrosine-protein kinase.	0.772
YAP1	WBP2	ENSNLEP00000031727	ENSNLEP00000033794	Uncharacterized protein.	WW domain binding protein 2.	0.583

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