STRINGSTRING
ROCK1 ROCK1 CX3CR1 CX3CR1 SPN SPN SELE SELE SELL SELL GCNT1 GCNT1 ADD2 ADD2 GOLPH3 GOLPH3 ITGB7 ITGB7 SELP SELP PODXL2 PODXL2 VCAM1 VCAM1 SELPLG SELPLG ITGA4 ITGA4 EXT1 EXT1 JAM2 JAM2 MADCAM1 MADCAM1 TNF TNF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1359 aa)
CX3CR1C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (386 aa)
SPNSialophorin. (400 aa)
SELESelectin E. (612 aa)
SELLL-selectin; Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. (385 aa)
GCNT1Glucosaminyl (N-acetyl) transferase 1. (428 aa)
ADD2Adducin 2. (726 aa)
GOLPH3Golgi phosphoprotein 3. (298 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (799 aa)
SELPSelectin P. (830 aa)
PODXL2Podocalyxin like 2. (598 aa)
VCAM1Vascular cell adhesion molecule 1. (739 aa)
SELPLGSelectin P ligand. (428 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (745 aa)
JAM2Junctional adhesion molecule 2. (312 aa)
MADCAM1Mucosal vascular addressin cell adhesion molecule 1. (398 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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