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| | NUBPL | Nucleotide binding protein like. (319 aa) |
| | AIFM3 | Apoptosis inducing factor mitochondria associated 3. (605 aa) |
| | BRIP1 | BRCA1 interacting protein C-terminal helicase 1. (1229 aa) |
| | GLRX5 | Glutaredoxin 5. (157 aa) |
| | MOCS1 | Molybdenum cofactor synthesis 1. (636 aa) |
| | CISD3 | CDGSH iron sulfur domain 3. (127 aa) |
| | KIF4A | Kinesin family member 4A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1212 aa) |
| | CDKAL1 | CDK5 regulatory subunit associated protein 1 like 1. (516 aa) |
| | LOC100581695 | Rieske domain-containing protein. (590 aa) |
| | PRIM2 | DNA primase subunit 2. (433 aa) |
| | CIAPIN1 | Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...] (312 aa) |
| | ACO1 | Aconitase 1; Belongs to the aconitase/IPM isomerase family. (889 aa) |
| | ABCE1 | ATP binding cassette subfamily E member 1. (599 aa) |
| | POLD1 | DNA polymerase. (1062 aa) |
| | NDUFV1 | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (385 aa) |
| | NDUFS8 | NADH:ubiquinone oxidoreductase core subunit S8. (218 aa) |
| | ISCU | Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (167 aa) |
| | NDUFV2 | NADH:ubiquinone oxidoreductase core subunit V2. (249 aa) |
| | NDUFS1 | NADH:ubiquinone oxidoreductase core subunit S1; Belongs to the complex I 75 kDa subunit family. (741 aa) |
| | UQCRFS1 | Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (274 aa) |
| | FECH | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. (423 aa) |
| | CIAO3 | Cytosolic iron-sulfur assembly component 3; Belongs to the NARF family. (475 aa) |
| | IREB2 | Iron responsive element binding protein 2; Belongs to the aconitase/IPM isomerase family. (964 aa) |
| | PPAT | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (545 aa) |
| | NUBP2 | Cytosolic Fe-S cluster assembly factor NUBP2; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. (271 aa) |
| | NTHL1 | Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (312 aa) |
| | CDK5RAP1 | CDK5 regulatory subunit associated protein 1. (601 aa) |
| | ABAT | 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (516 aa) |
| | NFU1 | NFU1 iron-sulfur cluster scaffold. (230 aa) |
| | NUBP1 | Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Implicated in the regulation of centrosome duplication; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (320 aa) |
| | NFS1 | Aminotran_5 domain-containing protein. (612 aa) |
| | DPYD | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (1025 aa) |
| | G1RMB2_NOMLE | Dna2 domain-containing protein. (678 aa) |
| | FDX2 | 2Fe-2S ferredoxin-type domain-containing protein. (186 aa) |
| | REV3L | REV3 like, DNA directed polymerase zeta catalytic subunit. (3107 aa) |
| | LOC100607540 | Flavodoxin-like domain-containing protein. (732 aa) |
| | SDHB | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (279 aa) |
| | RFESD | Rieske domain-containing protein. (210 aa) |
| | NDUFS2 | NADH:ubiquinone oxidoreductase core subunit S2; Belongs to the complex I 49 kDa subunit family. (465 aa) |
| | RSAD2 | Radical S-adenosyl methionine domain containing 2. (361 aa) |
| | ACO2 | Aconitase 2. (800 aa) |
| | ISCA2 | Iron-sulfur cluster assembly 2. (154 aa) |
| | SIVA1 | Apoptosis regulatory protein Siva; Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl- x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis. (175 aa) |
| | ELP3 | Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (547 aa) |
| | KIF4B | Kinesin family member 4B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1171 aa) |
| | GLRX2 | Glutaredoxin domain-containing protein. (164 aa) |
| | GLRX3 | Uncharacterized protein. (335 aa) |
| | RSAD1 | Radical S-adenosyl methionine domain-containing protein; May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen- III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L- methionine; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (442 aa) |
| | SERP1 | Stress-associated endoplasmic reticulum protein; May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation. Belongs to the RAMP4 family. (66 aa) |
| | ERCC2 | Helicase ATP-binding domain-containing protein. (625 aa) |
| | EXO5 | Exonuclease 5. (373 aa) |
| | INO80D | INO80 complex subunit D. (1027 aa) |
| | ENSNLEP00000027644 | Uncharacterized protein. (134 aa) |
| | LOC100580366 | Radical S-adenosyl methionine domain-containing protein; May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen- III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L- methionine; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (447 aa) |
| | ENSNLEP00000027909 | Fe-S_biosyn domain-containing protein. (117 aa) |
| | FXN | Uncharacterized protein. (196 aa) |
| | POLE | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2264 aa) |
| | LIAS | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (372 aa) |
| | CISD2 | ZnF_CDGSH domain-containing protein. (143 aa) |
| | AOX1 | Aldehyde oxidase 1. (1338 aa) |
| | BOLA2B | Uncharacterized protein; Belongs to the BolA/IbaG family. (152 aa) |
| | ENSNLEP00000032560 | Nfu_N domain-containing protein. (232 aa) |
| | FDX1 | Ferredoxin 1. (184 aa) |
| | MUTYH | Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. (591 aa) |
| | ISCA1 | Iron-sulfur cluster assembly 1. (129 aa) |
| | CISD1 | CDGSH iron sulfur domain 1. (108 aa) |
| | ENSNLEP00000035742 | ABC transporter domain-containing protein. (189 aa) |
| | ENSNLEP00000035899 | Uncharacterized protein. (321 aa) |
| | LOC100583419 | FAD-binding PCMH-type domain-containing protein. (1085 aa) |
| | CIAPIN1-2 | Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...] (297 aa) |
| | DPH2 | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2. (489 aa) |
| | LOC100579692 | Radical S-adenosyl methionine domain-containing protein; May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen- III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L- methionine; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (437 aa) |
| | DDX11 | DEAD/H-box helicase 11. (965 aa) |
| | NDUFS7 | Oxidored_q6 domain-containing protein; Belongs to the complex I 20 kDa subunit family. (176 aa) |
| | ENSNLEP00000037793 | Uncharacterized protein. (122 aa) |
| | ENSNLEP00000038989 | Uncharacterized protein. (64 aa) |
| | ENSNLEP00000040645 | Fe-S_biosyn domain-containing protein. (114 aa) |
| | DPH1 | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. (443 aa) |
| | ENSNLEP00000041358 | Uncharacterized protein. (191 aa) |
| | XDH | Xanthine dehydrogenase. (1271 aa) |
| | ETFDH | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (619 aa) |
| | SERP2 | Stress-associated endoplasmic reticulum protein; May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation. Belongs to the RAMP4 family. (65 aa) |
| | LOC105740713 | 2Fe-2S ferredoxin-type domain-containing protein. (172 aa) |
| | ENSNLEP00000045065 | Fe-S_biosyn domain-containing protein. (155 aa) |
| | ENSNLEP00000045560 | Uncharacterized protein. (723 aa) |
| | RTEL1 | Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1316 aa) |
| | ENSNLEP00000046132 | Elp3 domain-containing protein. (343 aa) |
| | ENSNLEP00000046574 | ZnF_CDGSH domain-containing protein. (100 aa) |
| | LOC100584186 | KH type-2 domain-containing protein. (260 aa) |
| | DNA2 | Uncharacterized protein. (97 aa) |
| | ENSNLEP00000048824 | Rieske domain-containing protein. (154 aa) |
| | ENSNLEP00000048874 | Uncharacterized protein. (178 aa) |
