STRINGSTRING
DAG1 DAG1 HYAL2 HYAL2 SLC1A5 SLC1A5 ARL8B ARL8B ENSNLEP00000037203 ENSNLEP00000037203 CHMP1A CHMP1A ENSNLEP00000036049 ENSNLEP00000036049 LOC100586164 LOC100586164 ITGAV ITGAV EGFR EGFR JPT2 JPT2 ENSNLEP00000035372 ENSNLEP00000035372 ENSNLEP00000035153 ENSNLEP00000035153 SLAMF1 SLAMF1 RPSA-2 RPSA-2 RNASEK RNASEK LOC100582469 LOC100582469 ITGB3 ITGB3 CAV1 CAV1 CBL CBL NECTIN1 NECTIN1 CLEC4G CLEC4G AVP AVP SIGLEC1 SIGLEC1 EPHA2 EPHA2 SCARB2 SCARB2 G1R9T9_NOMLE G1R9T9_NOMLE LRRC15 LRRC15 G1RC58_NOMLE G1RC58_NOMLE CDHR3 CDHR3 SLC52A1 SLC52A1 VAPB VAPB ACE2 ACE2 BCL2L1 BCL2L1 LOC101176801 LOC101176801 AXL AXL EFNB3 EFNB3 CR2 CR2 SRC SRC NCAM1 NCAM1 LOC100584981 LOC100584981 GYPA GYPA HSP90AB1 HSP90AB1 CHMP2A CHMP2A ENSNLEP00000027232 ENSNLEP00000027232 ENSNLEP00000026584 ENSNLEP00000026584 LAMP1 LAMP1 CD209 CD209 CLEC4M CLEC4M NECTIN2 NECTIN2 DDB1 DDB1 PLSCR1 PLSCR1 LOC101176233 LOC101176233 ITGB6 ITGB6 ENSNLEP00000025813 ENSNLEP00000025813 RAB7A RAB7A NRP1 NRP1 SMPD1 SMPD1 SIVA1 SIVA1 XPR1 XPR1 CHMP7 CHMP7 CTSB CTSB THOC2 THOC2 IFIT1 IFIT1 ICAM1 ICAM1 ANPEP ANPEP THOC7 THOC7 CAV2 CAV2 TCP1 TCP1 CHMP5 CHMP5 F11R F11R ATG7 ATG7 DYNLT1 DYNLT1 SLC52A2 SLC52A2 PGLYRP3 PGLYRP3 GAS6 GAS6 CHMP4B CHMP4B PIKFYVE PIKFYVE LOC100604168 LOC100604168 PVR PVR THOC6 THOC6 ENSNLEP00000030944 ENSNLEP00000030944 UVRAG UVRAG ENSNLEP00000030421 ENSNLEP00000030421 ENSNLEP00000030200 ENSNLEP00000030200 TSG101 TSG101 ITGB7 ITGB7 ITGA5 ITGA5 VPS37B VPS37B SLC10A1 SLC10A1 WWP1 WWP1 TRIM31 TRIM31 ENSNLEP00000042917 ENSNLEP00000042917 CHMP6 CHMP6 NUP153 NUP153 ITGA2 ITGA2 THOC1 THOC1 SELPLG SELPLG CLDN1 CLDN1 NPC1 NPC1 TPCN2 TPCN2 PPID PPID GRK2 GRK2 PC PC DDX39B DDX39B ZNF502 ZNF502 ZNF639 ZNF639 RPSA RPSA WWP2 WWP2 VPS4A VPS4A CTSL CTSL CD80 CD80 TYRO3 TYRO3 VPS18 VPS18 TRIM62 TRIM62 THOC5 THOC5 PHB PHB CHMP4C CHMP4C DPP4 DPP4 PGLYRP1 PGLYRP1 CLEC5A CLEC5A TNFRSF4 TNFRSF4 G1QH14_NOMLE G1QH14_NOMLE PGLYRP2 PGLYRP2 CD86 CD86 INSR INSR AVPR1B AVPR1B THOC3 THOC3 BSG BSG CD55 CD55 NECTIN4 NECTIN4 CLDN9 CLDN9 ENSNLEP00000043017 ENSNLEP00000043017 AGTR1 AGTR1 SCARB1 SCARB1 EPS15 EPS15 TRIM25 TRIM25 ITCH ITCH KPNA3 KPNA3 ITGB5 ITGB5 ENSNLEP00000046375 ENSNLEP00000046375 CHMP2B CHMP2B LOC100583249 LOC100583249 HAVCR1 HAVCR1 LOC101179478 LOC101179478 IDE IDE VAMP8 VAMP8 EFNB2 EFNB2 ALYREF ALYREF ENSNLEP00000041120 ENSNLEP00000041120 SLC20A2 SLC20A2 TNFRSF14 TNFRSF14 HTR2A HTR2A LDLR LDLR SLC3A2 SLC3A2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DAG1Dystroglycan 1. (895 aa)
HYAL2Hyaluronidase. (473 aa)
SLC1A5Amino acid transporter. (446 aa)
ARL8BADP ribosylation factor like GTPase 8B; Belongs to the small GTPase superfamily. Arf family. (186 aa)
ENSNLEP00000037203Prohibitin. (260 aa)
CHMP1ACharged multivesicular body protein 1A. (184 aa)
ENSNLEP00000036049Ig-like domain-containing protein. (299 aa)
LOC100586164Uncharacterized protein. (182 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1008 aa)
EGFRReceptor protein-tyrosine kinase. (1206 aa)
JPT2Uncharacterized protein. (79 aa)
ENSNLEP00000035372TGF_BETA_2 domain-containing protein. (392 aa)
ENSNLEP00000035153Prohibitin. (261 aa)
SLAMF1Signaling lymphocytic activation molecule family member 1. (331 aa)
RPSA-240S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteri [...] (291 aa)
RNASEKUncharacterized protein. (207 aa)
LOC10058246940S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteri [...] (294 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (806 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
CBLCbl proto-oncogene. (905 aa)
NECTIN1Nectin cell adhesion molecule 1. (515 aa)
CLEC4GC-type lectin domain-containing protein. (230 aa)
AVPArginine vasopressin; Belongs to the vasopressin/oxytocin family. (164 aa)
SIGLEC1Sialic acid binding Ig like lectin 1. (1601 aa)
EPHA2EPH receptor A2. (976 aa)
SCARB2Scavenger receptor class B member 2; Belongs to the CD36 family. (443 aa)
G1R9T9_NOMLEUncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (784 aa)
LRRC15Leucine rich repeat containing 15. (587 aa)
G1RC58_NOMLESERPIN domain-containing protein; Belongs to the serpin family. (321 aa)
CDHR3Cadherin related family member 3. (885 aa)
SLC52A1Solute carrier family 52 member 1. (410 aa)
VAPBVAMP associated protein B and C. (243 aa)
ACE2Angiotensin-converting enzyme. (805 aa)
BCL2L1BCL2 like 1. (217 aa)
LOC101176801Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (215 aa)
AXLReceptor protein-tyrosine kinase. (860 aa)
EFNB3Ephrin RBD domain-containing protein; Belongs to the ephrin family. (287 aa)
CR2Complement C3d receptor 2. (1092 aa)
SRCTyrosine-protein kinase. (537 aa)
NCAM1Neural cell adhesion molecule 1. (884 aa)
LOC10058498140S_SA_C domain-containing protein; Belongs to the universal ribosomal protein uS2 family. (262 aa)
GYPAGlycophorin. (118 aa)
HSP90AB1Heat shock protein 90 alpha family class B member 1. (665 aa)
CHMP2ACharged multivesicular body protein 2A. (229 aa)
ENSNLEP0000002723240S_SA_C domain-containing protein; Belongs to the universal ribosomal protein uS2 family. (206 aa)
ENSNLEP00000026584Uncharacterized protein. (141 aa)
LAMP1Lysosomal associated membrane protein 1. (416 aa)
CD209CD209 molecule. (358 aa)
CLEC4MC-type lectin domain family 4 member M. (375 aa)
NECTIN2Uncharacterized protein. (356 aa)
DDB1Damage specific DNA binding protein 1. (1139 aa)
PLSCR1Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (318 aa)
LOC101176233Uncharacterized protein. (880 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (788 aa)
ENSNLEP00000025813Prohibitin. (188 aa)
RAB7ARAB7A, member RAS oncogene family. (207 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (901 aa)
SMPD1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (624 aa)
SIVA1Apoptosis regulatory protein Siva; Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl- x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis. (175 aa)
XPR1Xenotropic and polytropic retrovirus receptor 1. (696 aa)
CHMP7Charged multivesicular body protein 7. (453 aa)
CTSBCathepsin B; Belongs to the peptidase C1 family. (339 aa)
THOC2THO complex 2. (1538 aa)
IFIT1Interferon induced protein with tetratricopeptide repeats 1. (479 aa)
ICAM1Intercellular adhesion molecule 1. (531 aa)
ANPEPAminopeptidase. (853 aa)
THOC7THO complex 7. (204 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (86 aa)
TCP1T-complex 1. (556 aa)
CHMP5Charged multivesicular body protein 5. (219 aa)
F11RF11 receptor. (299 aa)
ATG7Autophagy related 7. (672 aa)
DYNLT1Uncharacterized protein. (106 aa)
SLC52A2Solute carrier family 52 member 2. (453 aa)
PGLYRP3Peptidoglycan recognition protein 3. (282 aa)
GAS6Growth arrest specific 6. (679 aa)
CHMP4BCharged multivesicular body protein 4B. (224 aa)
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (2098 aa)
LOC100604168MSP domain-containing protein. (243 aa)
PVRPVR cell adhesion molecule. (372 aa)
THOC6THO complex 6. (341 aa)
ENSNLEP00000030944Prohibitin. (220 aa)
UVRAGUV radiation resistance associated. (699 aa)
ENSNLEP00000030421Uncharacterized protein. (190 aa)
ENSNLEP0000003020040S_SA_C domain-containing protein; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits; Belongs to the universal ribosomal protein uS2 family. (281 aa)
TSG101Tumor susceptibility 101. (390 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (799 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1038 aa)
VPS37BVPS37B subunit of ESCRT-I. (284 aa)
SLC10A1Solute carrier family 10 member 1. (325 aa)
WWP1E3 ubiquitin-protein ligase. (922 aa)
TRIM31Tripartite motif containing 31. (475 aa)
ENSNLEP00000042917Prohibitin. (131 aa)
CHMP6Uncharacterized protein. (192 aa)
NUP153Nucleoporin 153. (1506 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1181 aa)
THOC1THO complex 1. (657 aa)
SELPLGSelectin P ligand. (428 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
NPC1NPC intracellular cholesterol transporter 1. (1221 aa)
TPCN2Uncharacterized protein. (735 aa)
PPIDPeptidylprolyl isomerase D. (370 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (589 aa)
PCUncharacterized protein. (1094 aa)
DDX39BDExD-box helicase 39B. (354 aa)
ZNF502Zinc finger protein 502. (544 aa)
ZNF639Zinc finger protein 639. (485 aa)
RPSA40S_SA_C domain-containing protein; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits; Belongs to the universal ribosomal protein uS2 family. (267 aa)
WWP2E3 ubiquitin-protein ligase. (821 aa)
VPS4AUncharacterized protein; Belongs to the AAA ATPase family. (506 aa)
CTSLCathepsin L; Belongs to the peptidase C1 family. (333 aa)
CD80CD80 molecule. (288 aa)
TYRO3TYRO3 protein tyrosine kinase. (760 aa)
VPS18VPS18 core subunit of CORVET and HOPS complexes. (972 aa)
TRIM62Tripartite motif containing 62. (475 aa)
THOC5THO complex 5. (682 aa)
PHBProhibitin. (272 aa)
CHMP4CCharged multivesicular body protein 4C. (233 aa)
DPP4Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (766 aa)
PGLYRP1Peptidoglycan-recognition protein; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Involved in innate immunity. (196 aa)
CLEC5AC-type lectin domain containing 5A. (188 aa)
TNFRSF4TNF receptor superfamily member 4. (277 aa)
G1QH14_NOMLEUncharacterized protein. (500 aa)
PGLYRP2PGRP domain-containing protein. (476 aa)
CD86CD86 molecule. (329 aa)
INSRInsulin receptor. (1232 aa)
AVPR1BVasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (426 aa)
THOC3THO complex 3. (350 aa)
BSGUncharacterized protein. (345 aa)
CD55Uncharacterized protein. (550 aa)
NECTIN4Nectin cell adhesion molecule 4. (413 aa)
CLDN9Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa)
ENSNLEP00000043017HATPase_c domain-containing protein. (648 aa)
AGTR1Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family. (394 aa)
SCARB1Scavenger receptor class B member 1; Belongs to the CD36 family. (550 aa)
EPS15Epidermal growth factor receptor pathway substrate 15. (899 aa)
TRIM25Tripartite motif containing 25. (630 aa)
ITCHE3 ubiquitin-protein ligase. (905 aa)
KPNA3Importin subunit alpha; Functions in nuclear protein import. (506 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (859 aa)
ENSNLEP00000046375Prohibitin. (169 aa)
CHMP2BCharged multivesicular body protein 2B. (217 aa)
LOC100583249E3 ubiquitin-protein ligase. (807 aa)
HAVCR1Ig-like domain-containing protein. (360 aa)
LOC101179478Uncharacterized protein. (104 aa)
IDEInsulin degrading enzyme. (976 aa)
VAMP8V-SNARE coiled-coil homology domain-containing protein. (116 aa)
EFNB2Ephrin B2; Belongs to the ephrin family. (299 aa)
ALYREFAly/REF export factor. (285 aa)
ENSNLEP00000041120Uncharacterized protein. (106 aa)
SLC20A2Phosphate transporter; Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport. Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. (620 aa)
TNFRSF14TNFR-Cys domain-containing protein. (231 aa)
HTR2A5-hydroxytryptamine receptor 2A. (471 aa)
LDLRUncharacterized protein. (839 aa)
SLC3A2Solute carrier family 3 member 2. (624 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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