63 items (Nomascus leucogenys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	DMTN	Dematin actin binding protein. (406 aa)
	BCAS3	BCAS3 microtubule associated cell migration factor. (950 aa)
	FERMT2	Fermitin family member 2. (693 aa)
	ROCK2	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa)
	FMN1	Formin 1. (1424 aa)
	DLC1	DLC1 Rho GTPase activating protein. (1528 aa)
	PTK2	Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1099 aa)
	TLN1	Talin 1. (2542 aa)
	COL16A1	LAM_G_DOMAIN domain-containing protein. (1472 aa)
	VEGFA	Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (393 aa)
	LIMS1	LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (397 aa)
	ENSNLEP00000029912	Uncharacterized protein. (121 aa)
	PHLDB2	Pleckstrin homology like domain family B member 2. (1253 aa)
	ENSNLEP00000027935	Uncharacterized protein. (181 aa)
	CLASP1	Cytoplasmic linker associated protein 1. (1538 aa)
	NRP1	Neuropilin; Belongs to the neuropilin family. (901 aa)
	ACTG1	Actin gamma 1. (378 aa)
	ACVRL1	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
	LIMCH1	LIM and calponin homology domains 1. (1467 aa)
	TEK	TEK receptor tyrosine kinase. (1124 aa)
	RAC1	Rac family small GTPase 1. (187 aa)
	SLK	STE20 like kinase. (1223 aa)
	MYOC	Myocilin. (526 aa)
	LDB1	LIM domain binding 1. (411 aa)
	PTPRJ	Protein tyrosine phosphatase receptor type J. (1282 aa)
	S100A10	S100 calcium binding protein A10; Belongs to the S-100 family. (97 aa)
	TSC1	TSC complex subunit 1. (1164 aa)
	SFRP1	Secreted frizzled related protein 1. (314 aa)
	ABL1	Tyrosine-protein kinase. (1006 aa)
	PTEN	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
	EPHA3	EPH receptor A3. (983 aa)
	EFNA5	Ephrin A5; Belongs to the ephrin family. (228 aa)
	GREM1	CTCK domain-containing protein. (143 aa)
	WDPCP	WD repeat containing planar cell polarity effector. (746 aa)
	SLC9A1	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (809 aa)
	GPM6B	Glycoprotein M6B. (305 aa)
	PEAK1	Pseudopodium enriched atypical kinase 1. (1747 aa)
	RCC2	Regulator of chromosome condensation 2. (427 aa)
	PTPRA	Receptor-type tyrosine-protein phosphatase alpha. (802 aa)
	CORO1C	Coronin; Belongs to the WD repeat coronin family. (444 aa)
	SDC4	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (198 aa)
	HRG	Histidine rich glycoprotein. (530 aa)
	DAPK3	Death associated protein kinase 3. (407 aa)
	CAMSAP3	CKK domain-containing protein. (248 aa)
	EPB41L5	Erythrocyte membrane protein band 4.1 like 5. (732 aa)
	APOD	Apolipoprotein D. (215 aa)
	ENSNLEP00000048758	Uncharacterized protein. (453 aa)
	SRC	Tyrosine-protein kinase. (537 aa)
	ARHGAP6	Rho GTPase activating protein 6. (973 aa)
	ITGB1BP1	Integrin subunit beta 1 binding protein 1. (200 aa)
	CLASP2	Uncharacterized protein. (1515 aa)
	DUSP22	Dual specificity phosphatase 22; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (205 aa)
	KDR	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1367 aa)
	THBS1	Thrombospondin 1. (1173 aa)
	ROCK1	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1359 aa)
	POLDIP2	DNA polymerase delta interacting protein 2. (368 aa)
	PPM1F	Protein phosphatase, Mg2+/Mn2+ dependent 1F. (454 aa)
	ENSNLEP00000042609	Uncharacterized protein. (168 aa)
	VCL	Vinculin. (1091 aa)
	SMAD3	Mothers against decapentaplegic homolog. (425 aa)
	THY1	Ig-like domain-containing protein. (216 aa)
	MACF1	Uncharacterized protein. (7315 aa)
	MAP4K4	Mitogen-activated protein kinase kinase kinase kinase 4. (1346 aa)

Your Current Organism:

Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL1	EFNA5	ENSNLEP00000015256	ENSNLEP00000013600	Tyrosine-protein kinase.	Ephrin A5; Belongs to the ephrin family.	0.469
ABL1	ENSNLEP00000027935	ENSNLEP00000015256	ENSNLEP00000027935	Tyrosine-protein kinase.	Uncharacterized protein.	0.450
ABL1	ENSNLEP00000042609	ENSNLEP00000015256	ENSNLEP00000042609	Tyrosine-protein kinase.	Uncharacterized protein.	0.450
ABL1	PTEN	ENSNLEP00000015256	ENSNLEP00000014741	Tyrosine-protein kinase.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.512
ABL1	RAC1	ENSNLEP00000015256	ENSNLEP00000019034	Tyrosine-protein kinase.	Rac family small GTPase 1.	0.450
ABL1	SRC	ENSNLEP00000015256	ENSNLEP00000048569	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.459
ABL1	VCL	ENSNLEP00000015256	ENSNLEP00000041781	Tyrosine-protein kinase.	Vinculin.	0.549
ACTG1	TLN1	ENSNLEP00000023255	ENSNLEP00000034100	Actin gamma 1.	Talin 1.	0.434
ACTG1	VCL	ENSNLEP00000023255	ENSNLEP00000041781	Actin gamma 1.	Vinculin.	0.621
ACVRL1	KDR	ENSNLEP00000021573	ENSNLEP00000044105	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.410
ACVRL1	SMAD3	ENSNLEP00000021573	ENSNLEP00000041430	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.566
ARHGAP6	ENSNLEP00000027935	ENSNLEP00000047931	ENSNLEP00000027935	Rho GTPase activating protein 6.	Uncharacterized protein.	0.447
ARHGAP6	ENSNLEP00000042609	ENSNLEP00000047931	ENSNLEP00000042609	Rho GTPase activating protein 6.	Uncharacterized protein.	0.447
ARHGAP6	RAC1	ENSNLEP00000047931	ENSNLEP00000019034	Rho GTPase activating protein 6.	Rac family small GTPase 1.	0.447
CAMSAP3	ENSNLEP00000029912	ENSNLEP00000001123	ENSNLEP00000029912	CKK domain-containing protein.	Uncharacterized protein.	0.626
CAMSAP3	MACF1	ENSNLEP00000001123	ENSNLEP00000041114	CKK domain-containing protein.	Uncharacterized protein.	0.626
CLASP1	PHLDB2	ENSNLEP00000025011	ENSNLEP00000028339	Cytoplasmic linker associated protein 1.	Pleckstrin homology like domain family B member 2.	0.488
CLASP2	ENSNLEP00000029912	ENSNLEP00000046676	ENSNLEP00000029912	Uncharacterized protein.	Uncharacterized protein.	0.402
CLASP2	MACF1	ENSNLEP00000046676	ENSNLEP00000041114	Uncharacterized protein.	Uncharacterized protein.	0.402
CLASP2	PHLDB2	ENSNLEP00000046676	ENSNLEP00000028339	Uncharacterized protein.	Pleckstrin homology like domain family B member 2.	0.692

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