STRINGSTRING
CACNG5 CACNG5 ROR2 ROR2 NPS NPS OPHN1 OPHN1 SHANK3 SHANK3 GRM6 GRM6 G1QLB3_NOMLE G1QLB3_NOMLE CLN3 CLN3 DISC1 DISC1 UCN UCN GRIN2B GRIN2B CDK5 CDK5 NLGN1 NLGN1 CACNG7 CACNG7 CACNG8 CACNG8 GRM2 GRM2 TSHZ3 TSHZ3 RAB3GAP1 RAB3GAP1 RELN RELN NLGN2 NLGN2 SERPINE2 SERPINE2 PLPPR4 PLPPR4 GRIK3 GRIK3 DKK1 DKK1 ATAD1 ATAD1 GRM8 GRM8 CACNG2 CACNG2 TNR TNR ADORA2A ADORA2A PTK2B PTK2B FRRS1L FRRS1L RNF167 RNF167 LRRK2 LRRK2 GLUL GLUL PTGS2 PTGS2 ENSNLEP00000024944 ENSNLEP00000024944 KMO KMO DRD3 DRD3 HCN1 HCN1 ENSNLEP00000027457 ENSNLEP00000027457 GRIK1 GRIK1 DGKZ DGKZ GRM1 GRM1 DTNBP1 DTNBP1 DRD2 DRD2 TPRG1L TPRG1L GRIK2 GRIK2 PSEN1 PSEN1 GRM5 GRM5 GRIN2D GRIN2D ENSNLEP00000032846 ENSNLEP00000032846 MAPK8IP2 MAPK8IP2 MEF2C MEF2C TPRG1 TPRG1 HOMER1 HOMER1 CACNG4 CACNG4 PLA2G6 PLA2G6 ENSNLEP00000036861 ENSNLEP00000036861 GRIN1 GRIN1 ENSNLEP00000037750 ENSNLEP00000037750 NRXN1 NRXN1 NLGN3 NLGN3 DRD1 DRD1 HTR2A HTR2A ENSNLEP00000039670 ENSNLEP00000039670 UNC13A UNC13A DGKI DGKI NTRK1 NTRK1 OXTR OXTR ENSNLEP00000048868 ENSNLEP00000048868 GRM4 GRM4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CACNG5Calcium voltage-gated channel auxiliary subunit gamma 5. (275 aa)
ROR2Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (915 aa)
NPSNeuropeptide S. (89 aa)
OPHN1Oligophrenin 1. (802 aa)
SHANK3SH3 and multiple ankyrin repeat domains 3. (1521 aa)
GRM6Glutamate metabotropic receptor 6. (865 aa)
G1QLB3_NOMLEC-C motif chemokine. (138 aa)
CLN3Battenin. (384 aa)
DISC1Uncharacterized protein. (202 aa)
UCNUrocortin. (124 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1335 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (320 aa)
NLGN1Neuroligin 1. (823 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (271 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (424 aa)
GRM2Glutamate metabotropic receptor 2. (873 aa)
TSHZ3Teashirt zinc finger homeobox 3. (1081 aa)
RAB3GAP1RAB3 GTPase activating protein catalytic subunit 1. (980 aa)
RELNReelin. (3460 aa)
NLGN2Neuroligin 2. (768 aa)
SERPINE2Serpin family E member 2; Belongs to the serpin family. (381 aa)
PLPPR4Phospholipid phosphatase related 4. (689 aa)
GRIK3Glutamate ionotropic receptor kainate type subunit 3. (887 aa)
DKK1Dickkopf-like protein 1. (266 aa)
ATAD1ATPase family AAA domain containing 1; Belongs to the AAA ATPase family. (364 aa)
GRM8Glutamate metabotropic receptor 8. (765 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
TNRTenascin R. (1348 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (412 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (871 aa)
FRRS1LFerric chelate reductase 1 like. (303 aa)
RNF167Ring finger protein 167. (351 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
GLULGlutamine synthetase. (373 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
ENSNLEP00000024944Uncharacterized protein. (179 aa)
KMOKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. (486 aa)
DRD3Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (400 aa)
HCN1Cyclic nucleotide-binding domain-containing protein. (628 aa)
ENSNLEP00000027457Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family. (329 aa)
GRIK1Glutamate ionotropic receptor kainate type subunit 1. (949 aa)
DGKZDiacylglycerol kinase. (895 aa)
GRM1Glutamate metabotropic receptor 1. (1195 aa)
DTNBP1Dystrobrevin binding protein 1. (350 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (445 aa)
TPRG1LTumor protein p63 regulated 1 like. (272 aa)
GRIK2Glutamate ionotropic receptor kainate type subunit 2. (908 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
GRM5Glutamate metabotropic receptor 5. (1210 aa)
GRIN2DUncharacterized protein. (1096 aa)
ENSNLEP00000032846ANF_receptor domain-containing protein. (199 aa)
MAPK8IP2PID domain-containing protein. (178 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
TPRG1Tumor protein p63 regulated 1. (275 aa)
HOMER1Homer scaffold protein 1. (377 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
PLA2G6Phospholipase A2 group VI. (805 aa)
ENSNLEP00000036861Uncharacterized protein. (119 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (888 aa)
ENSNLEP00000037750Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family. (341 aa)
NRXN1Neurexin 1. (1547 aa)
NLGN3Neuroligin 3. (912 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
HTR2A5-hydroxytryptamine receptor 2A. (471 aa)
ENSNLEP00000039670Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family. (334 aa)
UNC13AUnc-13 homolog A. (1460 aa)
DGKIDiacylglycerol kinase. (1026 aa)
NTRK1Tyrosine-protein kinase receptor. (787 aa)
OXTROxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (389 aa)
ENSNLEP00000048868AAA domain-containing protein. (306 aa)
GRM4Glutamate metabotropic receptor 4. (888 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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