STRINGSTRING
SLC4A5 SLC4A5 AVPR1B AVPR1B EDN1 EDN1 SLC12A8 SLC12A8 ATP6V1B2 ATP6V1B2 ATP4B ATP4B OTC OTC CLN3 CLN3 ATP6AP2 ATP6AP2 VPS33A VPS33A IL1A IL1A LACC1 LACC1 MAPK3 MAPK3 ATP6V0A2 ATP6V0A2 SLC12A3 SLC12A3 SLC9A7 SLC9A7 CA2 CA2 HVCN1 HVCN1 CHP1 CHP1 SCN7A SCN7A KCNH2 KCNH2 TFAP2B TFAP2B RHAG RHAG SLC9C1 SLC9C1 SLC9A5 SLC9A5 EXT1 EXT1 SLC9A9 SLC9A9 SLC12A4 SLC12A4 GRN GRN SLC4A1 SLC4A1 GPR89A GPR89A EDNRA EDNRA G1R1Y8_NOMLE G1R1Y8_NOMLE SLC12A1 SLC12A1 DMXL2 DMXL2 TCIRG1 TCIRG1 SLC26A6 SLC26A6 SLC9A8 SLC9A8 MAFG MAFG AVP AVP SLC4A4 SLC4A4 RAB20 RAB20 TMEM165 TMEM165 KLHL3 KLHL3 SLC11A1 SLC11A1 SLC26A3 SLC26A3 SLC26A4 SLC26A4 PDK2 PDK2 CLIC4 CLIC4 RHCE RHCE SLC4A9 SLC4A9 ATP6V0C ATP6V0C SLC9A1 SLC9A1 SLC4A3 SLC4A3 ATP1B2 ATP1B2 CXorf21 CXorf21 ATP6V1B1 ATP6V1B1 CCDC115 CCDC115 G1RI26_NOMLE G1RI26_NOMLE SLC9A3 SLC9A3 SLC12A7 SLC12A7 ATP4A ATP4A CFTR CFTR SLC12A9 SLC12A9 PPT1 PPT1 SLC12A2 SLC12A2 RHBG RHBG ATP6AP1L ATP6AP1L SLAMF8 SLAMF8 ATP1A3 ATP1A3 ATP1A4 ATP1A4 ATP12A ATP12A ATP6V0A4 ATP6V0A4 ATP6AP1 ATP6AP1 TMPRSS3 TMPRSS3 SLC9A4 SLC9A4 SLC9A2 SLC9A2 ATP1B1 ATP1B1 FASLG FASLG SLC9C2 SLC9C2 PDK4 PDK4 RAB38 RAB38 TMEM106B TMEM106B EDNRB EDNRB AQP11 AQP11 AVPR1A AVPR1A SLC4A8 SLC4A8 LRRK2 LRRK2 EXT2 EXT2 TMEM9 TMEM9 MC3R MC3R M3Z9R9_NOMLE M3Z9R9_NOMLE SLC9B1 SLC9B1 ENSNLEP00000025216 ENSNLEP00000025216 ATP6V0B ATP6V0B RAB7A RAB7A ATP5F1B ATP5F1B MAPK1 MAPK1 SNAPIN SNAPIN UMOD UMOD TM9SF4 TM9SF4 CLN6 CLN6 MLLT6 MLLT6 ENSNLEP00000028566 ENSNLEP00000028566 SLC12A5 SLC12A5 KCNJ2 KCNJ2 RAB39A RAB39A KCNMA1 KCNMA1 SLC8A1 SLC8A1 SLC9A6 SLC9A6 SLC4A7 SLC4A7 RNASEK RNASEK SCNN1G SCNN1G ATP1A1 ATP1A1 CCKBR CCKBR RHCG RHCG ENSNLEP00000035464 ENSNLEP00000035464 BCL2 BCL2 SCNN1A SCNN1A ATP6V1H ATP6V1H TMEM175 TMEM175 ENSNLEP00000038540 ENSNLEP00000038540 ATP1B3 ATP1B3 ENSNLEP00000039267 ENSNLEP00000039267 ENSNLEP00000039398 ENSNLEP00000039398 NOX1 NOX1 CA7 CA7 SCNN1D SCNN1D ENSNLEP00000041886 ENSNLEP00000041886 ENSNLEP00000043731 ENSNLEP00000043731 SLC1A3 SLC1A3 SLC4A10 SLC4A10 ENSNLEP00000044651 ENSNLEP00000044651 CYP4F12 CYP4F12 KCTD7 KCTD7 WNK1 WNK1 UBE3A UBE3A ATP1A2 ATP1A2 ATP6V1F ATP6V1F SLC12A6 SLC12A6 DMXL1 DMXL1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
SLC4A5Anion exchange protein. (1136 aa)
AVPR1BVasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (426 aa)
EDN1Endothelin 1. (211 aa)
SLC12A8Solute carrier family 12 member 8. (713 aa)
ATP6V1B2Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (528 aa)
ATP4BATPase H+/K+ transporting subunit beta. (237 aa)
OTCOrnithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (354 aa)
CLN3Battenin. (384 aa)
ATP6AP2ATPase H+ transporting accessory protein 2. (350 aa)
VPS33AVPS33A core subunit of CORVET and HOPS complexes; Belongs to the STXBP/unc-18/SEC1 family. (596 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (247 aa)
LACC1Uncharacterized protein. (430 aa)
MAPK3Mitogen-activated protein kinase. (278 aa)
ATP6V0A2V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (856 aa)
SLC12A3Solute carrier family 12 member 3. (1026 aa)
SLC9A7Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (724 aa)
CA2Carbonic anhydrase 2; Belongs to the alpha-carbonic anhydrase family. (260 aa)
HVCN1Hydrogen voltage gated channel 1. (266 aa)
CHP1Calcineurin like EF-hand protein 1. (195 aa)
SCN7ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1682 aa)
KCNH2Potassium voltage-gated channel subfamily H member 2. (1085 aa)
TFAP2BTranscription factor AP-2 beta. (460 aa)
RHAGRh associated glycoprotein; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. (428 aa)
SLC9C1Solute carrier family 9 member C1. (1177 aa)
SLC9A5Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (778 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (745 aa)
SLC9A9Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (645 aa)
SLC12A4Solute carrier family 12 member 4. (1075 aa)
GRNGranulin precursor. (593 aa)
SLC4A1Anion exchange protein. (870 aa)
GPR89AUncharacterized protein. (430 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
G1R1Y8_NOMLENa_H_Exchanger domain-containing protein. (314 aa)
SLC12A1Solute carrier family 12 member 1. (1047 aa)
DMXL2Dmx like 2. (3037 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (832 aa)
SLC26A6Solute carrier family 26 member 6. (759 aa)
SLC9A8Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (581 aa)
MAFGMAF bZIP transcription factor G. (162 aa)
AVPArginine vasopressin; Belongs to the vasopressin/oxytocin family. (164 aa)
SLC4A4Anion exchange protein. (1084 aa)
RAB20RAB20, member RAS oncogene family. (234 aa)
TMEM165GDT1 family protein. (324 aa)
KLHL3Kelch like family member 3. (587 aa)
SLC11A1Solute carrier family 11 member 1. (550 aa)
SLC26A3Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (759 aa)
SLC26A4Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (780 aa)
PDK2Protein-serine/threonine kinase. (415 aa)
CLIC4Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (253 aa)
RHCEAmmonium_transp domain-containing protein; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. (187 aa)
SLC4A9Anion exchange protein. (962 aa)
ATP6V0CV-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (809 aa)
SLC4A3Anion exchange protein. (1097 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
CXorf21Chromosome X open reading frame 21. (301 aa)
ATP6V1B1ATPase H+ transporting V1 subunit B1. (483 aa)
CCDC115Uncharacterized protein. (193 aa)
G1RI26_NOMLEUncharacterized protein. (991 aa)
SLC9A3Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (790 aa)
SLC12A7Solute carrier family 12 member 7. (1077 aa)
ATP4AUncharacterized protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (920 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1480 aa)
SLC12A9Solute carrier family 12 member 9. (811 aa)
PPT1Palmitoyl-protein thioesterase 1. (326 aa)
SLC12A2Solute carrier family 12 member 2. (1202 aa)
RHBGRh family B glycoprotein (gene/pseudogene); Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. (453 aa)
ATP6AP1LATPase H+ transporting accessory protein 1 like. (204 aa)
SLAMF8SLAM family member 8. (249 aa)
ATP1A3Sodium/potassium-transporting ATPase subunit alpha. (952 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (963 aa)
ATP12ASodium/potassium-transporting ATPase subunit alpha. (1002 aa)
ATP6V0A4V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (840 aa)
ATP6AP1ATPase H+ transporting accessory protein 1. (468 aa)
TMPRSS3Transmembrane serine protease 3; Belongs to the peptidase S1 family. (436 aa)
SLC9A4Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (798 aa)
SLC9A2Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (812 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
FASLGTumor necrosis factor ligand 1A; Belongs to the tumor necrosis factor family. (280 aa)
SLC9C2Solute carrier family 9 member C2 (putative). (1106 aa)
PDK4Protein-serine/threonine kinase. (411 aa)
RAB38RAB38, member RAS oncogene family. (211 aa)
TMEM106BTransmembrane protein 106B. (274 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (532 aa)
AQP11Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (271 aa)
AVPR1AVasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. (405 aa)
SLC4A8Anion exchange protein. (1093 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
EXT2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (751 aa)
TMEM9Transmembrane protein 9. (183 aa)
MC3RMelanocortin 3 receptor. (323 aa)
M3Z9R9_NOMLEAmmonium_transp domain-containing protein; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. (147 aa)
SLC9B1Solute carrier family 9 member B1. (515 aa)
ENSNLEP00000025216Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (256 aa)
ATP6V0BUncharacterized protein; Belongs to the V-ATPase proteolipid subunit family. (258 aa)
RAB7ARAB7A, member RAS oncogene family. (207 aa)
ATP5F1BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (509 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (341 aa)
SNAPINSNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa)
UMODUromodulin. (676 aa)
TM9SF4Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (642 aa)
CLN6CLN6 transmembrane ER protein. (342 aa)
MLLT6MLLT6, PHD finger containing. (1069 aa)
ENSNLEP00000028566Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (243 aa)
SLC12A5Solute carrier family 12 member 5. (1139 aa)
KCNJ2Potassium voltage-gated channel subfamily J member 2. (427 aa)
RAB39ARAB39A, member RAS oncogene family. (217 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1289 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (972 aa)
SLC9A6Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (669 aa)
SLC4A7Anion exchange protein. (1259 aa)
RNASEKUncharacterized protein. (207 aa)
SCNN1GSodium channel epithelial 1 gamma subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (633 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1027 aa)
CCKBRG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (514 aa)
RHCGRh family C glycoprotein; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. (457 aa)
ENSNLEP00000035464Uncharacterized protein. (276 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
SCNN1AUncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (661 aa)
ATP6V1HV-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (483 aa)
TMEM175Uncharacterized protein. (74 aa)
ENSNLEP00000038540Uncharacterized protein. (347 aa)
ATP1B3Uncharacterized protein. (89 aa)
ENSNLEP00000039267Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (234 aa)
ENSNLEP00000039398Uncharacterized protein. (421 aa)
NOX1NADPH oxidase 1. (564 aa)
CA7Carbonic anhydrase 7; Belongs to the alpha-carbonic anhydrase family. (264 aa)
SCNN1DSodium channel epithelial 1 delta subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (777 aa)
ENSNLEP00000041886Ion_trans domain-containing protein; Belongs to the potassium channel family. (359 aa)
ENSNLEP00000043731Uncharacterized protein. (166 aa)
SLC1A3Amino acid transporter. (542 aa)
SLC4A10Anion exchange protein. (1140 aa)
ENSNLEP00000044651EF-hand domain-containing protein. (184 aa)
CYP4F12Cytochrome P450 family 4 subfamily F member 12; Belongs to the cytochrome P450 family. (458 aa)
KCTD7Potassium channel tetramerization domain containing 7. (256 aa)
WNK1WNK lysine deficient protein kinase 1. (2833 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (881 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
ATP6V1FV-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (147 aa)
SLC12A6Solute carrier family 12 member 6. (1150 aa)
DMXL1Dmx like 1. (3039 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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