STRINGSTRING
MEF2C MEF2C NRG1 NRG1 ENSNLEP00000032543 ENSNLEP00000032543 YAP1 YAP1 BMPR1A BMPR1A MAPK14 MAPK14 GLI1 GLI1 FGFR2 FGFR2 HEY2 HEY2 FGF9 FGF9 WNT2 WNT2 PIM1 PIM1 TGFBR3 TGFBR3 BMP10 BMP10 NOTCH1 NOTCH1 ERBB4 ERBB4 GATA6 GATA6 ZFPM2 ZFPM2 TBX20 TBX20 TBX2 TBX2 TBX5 TBX5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MEF2CMyocyte enhancer factor 2C. (483 aa)
NRG1Neuregulin 1. (713 aa)
ENSNLEP00000032543Uncharacterized protein. (168 aa)
YAP1Uncharacterized protein. (418 aa)
BMPR1ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (533 aa)
MAPK14Mitogen-activated protein kinase. (321 aa)
GLI1GLI family zinc finger 1. (1106 aa)
FGFR2Fibroblast growth factor receptor. (820 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
WNT2Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa)
PIM1Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (402 aa)
TGFBR3Transforming growth factor beta receptor 3. (860 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
NOTCH1Notch receptor 1. (2451 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
GATA6Uncharacterized protein. (452 aa)
ZFPM2Zinc finger protein, FOG family member 2. (1151 aa)
TBX20T-box transcription factor 20. (447 aa)
TBX2T-box transcription factor 2. (647 aa)
TBX5T-box transcription factor 5. (508 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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