STRINGSTRING
EGR3 EGR3 ABCC1 ABCC1 CRKL CRKL SYK SYK FLT1 FLT1 BSG BSG CRK CRK G1QJP9_NOMLE G1QJP9_NOMLE CXCR3 CXCR3 CALCA CALCA ANXA1 ANXA1 VAV3 VAV3 G1QLB3_NOMLE G1QLB3_NOMLE CCL7 CCL7 CCL11 CCL11 CCL8 CCL8 CCL13 CCL13 CCL1 CCL1 LOC100596700 LOC100596700 TAFA4 TAFA4 ADAM8 ADAM8 CXADR CXADR ITGB2 ITGB2 CX3CL1 CX3CL1 CCL17 CCL17 G1QRB3_NOMLE G1QRB3_NOMLE LYST LYST ACKR4 ACKR4 EPHB1 EPHB1 CYP7B1 CYP7B1 PPIA PPIA PTPRO PTPRO MSMP MSMP CCL21 CCL21 CCN3 CCN3 TREM1 TREM1 GAB1 GAB1 LOC100580385 LOC100580385 XCR1 XCR1 CCR1 CCR1 LBP LBP CORO1B CORO1B PRKCD PRKCD LOC100580192 LOC100580192 JAML JAML SLC37A4 SLC37A4 EPHA2 EPHA2 CCRL2 CCRL2 IL17RA IL17RA CXCL6 CXCL6 PF4V1 PF4V1 PPBP PPBP CXCL5 CXCL5 CXCL3 CXCL3 CXCL2 CXCL2 CXCL11 CXCL11 CXCL9 CXCL9 CXCL10 CXCL10 ARHGEF16 ARHGEF16 CXCL13 CXCL13 CXCL14 CXCL14 KIT KIT PLEKHG5 PLEKHG5 CCL24 CCL24 CCL26 CCL26 TNFRSF11A TNFRSF11A PIK3CG PIK3CG HBEGF HBEGF PIK3CD PIK3CD SCG2 SCG2 PDGFRB PDGFRB GAS6 GAS6 S100A9 S100A9 S100A12 S100A12 CCL28 CCL28 CCL27 CCL27 SFTPD SFTPD ACKR3 ACKR3 CXCL17 CXCL17 ITGA1 ITGA1 C10orf99 C10orf99 DOCK4 DOCK4 CSF3R CSF3R SEMA5A SEMA5A CCR10 CCR10 PRKCQ PRKCQ VCAM1 VCAM1 LOX LOX EDN2 EDN2 SLC12A2 SLC12A2 PPIB PPIB LGALS3 LGALS3 SLAMF8 SLAMF8 SBDS SBDS TGFB2 TGFB2 CCL5 CCL5 CCL16 CCL16 CCL14 CCL14 CCL15 CCL15 CCL23 CCL23 CCL18 CCL18 LOC100602388 LOC100602388 CCL4 CCL4 GBF1 GBF1 DEFB130B DEFB130B LOC100604016 LOC100604016 PDGFB PDGFB PLA2G1B PLA2G1B DPEP1 DPEP1 ALOX5 ALOX5 TNFSF14 TNFSF14 EDNRB EDNRB NINJ1 NINJ1 C5 C5 CHGA CHGA LPAR1 LPAR1 PARVA PARVA NR4A1 NR4A1 BIN2 BIN2 ANO6 ANO6 C5AR1 C5AR1 CCR4 CCR4 ACKR2 ACKR2 CH25H CH25H HRH1 HRH1 PIKFYVE PIKFYVE SRP54 SRP54 HGF HGF PREX1 PREX1 NRP1 NRP1 ENG ENG TNFSF11 TNFSF11 LOC100607679 LOC100607679 IL16 IL16 LOC100599403 LOC100599403 FCER1G FCER1G PTN PTN VAV1 VAV1 PDE4B PDE4B CCL25 CCL25 RAB13 RAB13 ENSNLEP00000028912 ENSNLEP00000028912 CTSG CTSG LOC100583930 LOC100583930 CORO1A CORO1A ENSNLEP00000032876 ENSNLEP00000032876 NCKAP1L NCKAP1L ELMO2 ELMO2 CXCL16 CXCL16 SLAMF1 SLAMF1 LEF1 LEF1 NUP85 NUP85 ENSNLEP00000035662 ENSNLEP00000035662 CCL20 CCL20 IL6R IL6R RHOG RHOG ENSNLEP00000036155 ENSNLEP00000036155 CXCR5 CXCR5 TRPM4 TRPM4 CXCR4 CXCR4 TRPM2 TRPM2 LOC100595480 LOC100595480 ENSNLEP00000038427 ENSNLEP00000038427 CXCL12 CXCL12 S1PR1 S1PR1 CCL22 CCL22 IL17RC IL17RC ENSNLEP00000040637 ENSNLEP00000040637 ENSNLEP00000040732 ENSNLEP00000040732 BCAR1 BCAR1 PIP5K1A PIP5K1A FFAR2 FFAR2 EDN3 EDN3 ENSNLEP00000041829 ENSNLEP00000041829 CCR6 CCR6 LOC100607085 LOC100607085 CX3CR1 CX3CR1 AGTR1 AGTR1 PF4 PF4 CCR9 CCR9 LOC100602058 LOC100602058 LOC100591994 LOC100591994 ENSNLEP00000044243 ENSNLEP00000044243 CCR7 CCR7 PLEC PLEC IL1B IL1B ENSNLEP00000045002 ENSNLEP00000045002 TPBG TPBG PLXNB3 PLXNB3 PIP5K1C PIP5K1C CXCL8 CXCL8 ENSNLEP00000046123 ENSNLEP00000046123 ITGA9 ITGA9 ENSNLEP00000046458 ENSNLEP00000046458 IL6 IL6 S100A8 S100A8 ENSNLEP00000047342 ENSNLEP00000047342 LOC100595821 LOC100595821 HSD3B7 HSD3B7 ARHGEF5 ARHGEF5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EGR3Early growth response 3. (387 aa)
ABCC1Uncharacterized protein. (1058 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
SYKTyrosine-protein kinase. (532 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa)
BSGUncharacterized protein. (345 aa)
CRKUncharacterized protein. (252 aa)
G1QJP9_NOMLEPeptidase S1 domain-containing protein. (178 aa)
CXCR3C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (368 aa)
CALCACalcitonin related polypeptide alpha. (141 aa)
ANXA1Annexin. (346 aa)
VAV3Vav guanine nucleotide exchange factor 3. (799 aa)
G1QLB3_NOMLEC-C motif chemokine. (138 aa)
CCL7C-C motif chemokine. (99 aa)
CCL11C-C motif chemokine. (97 aa)
CCL8C-C motif chemokine. (99 aa)
CCL13C-C motif chemokine. (98 aa)
CCL1C-C motif chemokine. (96 aa)
LOC100596700Uncharacterized protein. (75 aa)
TAFA4TAFA chemokine like family member 4. (140 aa)
ADAM8Uncharacterized protein. (678 aa)
CXADRCXADR Ig-like cell adhesion molecule. (365 aa)
ITGB2Integrin beta. (762 aa)
CX3CL1C-X3-C motif chemokine ligand 1. (397 aa)
CCL17C-C motif chemokine. (94 aa)
G1QRB3_NOMLEC-C motif chemokine. (79 aa)
LYSTLysosomal trafficking regulator. (3801 aa)
ACKR4Atypical chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (350 aa)
EPHB1EPH receptor B1. (984 aa)
CYP7B1Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. (506 aa)
PPIAPeptidyl-prolyl cis-trans isomerase A, N-terminally processed; PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding; Belongs to the cyclophilin-type PPIase family. PPIase A subfamily. (165 aa)
PTPROProtein tyrosine phosphatase receptor type O. (1183 aa)
MSMPBeta-microseminoprotein. (139 aa)
CCL21C-C motif chemokine ligand 21. (134 aa)
CCN3Cellular communication network factor 3. (357 aa)
TREM1Triggering receptor expressed on myeloid cells 1. (234 aa)
GAB1GRB2 associated binding protein 1. (724 aa)
LOC100580385SCY domain-containing protein. (114 aa)
XCR1X-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (333 aa)
CCR1C-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (355 aa)
LBPLipopolysaccharide binding protein. (481 aa)
CORO1BCoronin; Belongs to the WD repeat coronin family. (481 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
LOC100580192G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (351 aa)
JAMLJunction adhesion molecule like. (394 aa)
SLC37A4Solute carrier family 37 member 4. (399 aa)
EPHA2EPH receptor A2. (976 aa)
CCRL2C-C motif chemokine receptor like 2; Belongs to the G-protein coupled receptor 1 family. (356 aa)
IL17RAInterleukin 17 receptor A. (817 aa)
CXCL6C-X-C motif chemokine. (114 aa)
PF4V1C-X-C motif chemokine. (101 aa)
PPBPC-X-C motif chemokine. (128 aa)
CXCL5C-X-C motif chemokine. (114 aa)
CXCL3C-X-C motif chemokine. (107 aa)
CXCL2C-X-C motif chemokine. (106 aa)
CXCL11C-X-C motif chemokine. (94 aa)
CXCL9C-X-C motif chemokine. (125 aa)
CXCL10C-X-C motif chemokine. (98 aa)
ARHGEF16Uncharacterized protein. (509 aa)
CXCL13C-X-C motif chemokine ligand 13. (109 aa)
CXCL14C-X-C motif chemokine ligand 14. (111 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (969 aa)
PLEKHG5Pleckstrin homology and RhoGEF domain containing G5. (1009 aa)
CCL24C-C motif chemokine ligand 24. (118 aa)
CCL26C-C motif chemokine. (94 aa)
TNFRSF11ATNF receptor superfamily member 11a. (595 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
PIK3CDPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family. (1077 aa)
SCG2Secretogranin II. (542 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
GAS6Growth arrest specific 6. (679 aa)
S100A9Protein S100; Belongs to the S-100 family. (112 aa)
S100A12S100 calcium binding protein A12; Belongs to the S-100 family. (91 aa)
CCL28C-C motif chemokine. (127 aa)
CCL27C-C motif chemokine ligand 27. (112 aa)
SFTPDSurfactant protein D. (375 aa)
ACKR3Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (362 aa)
CXCL17C-X-C motif chemokine ligand 17. (119 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1179 aa)
C10orf99Chromosome 10 open reading frame 99. (81 aa)
DOCK4Dedicator of cytokinesis 4; Belongs to the DOCK family. (2019 aa)
CSF3RColony stimulating factor 3 receptor. (857 aa)
SEMA5ASemaphorin 5A. (1074 aa)
CCR10C-C motif chemokine receptor 10; Belongs to the G-protein coupled receptor 1 family. (362 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
VCAM1Vascular cell adhesion molecule 1. (739 aa)
LOXLysyl oxidase. (417 aa)
EDN2Endothelin 2. (177 aa)
SLC12A2Solute carrier family 12 member 2. (1202 aa)
PPIBPeptidylprolyl isomerase B. (184 aa)
LGALS3Galectin. (250 aa)
SLAMF8SLAM family member 8. (249 aa)
SBDSSBDS ribosome maturation factor. (250 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
CCL5C-C motif chemokine. (91 aa)
CCL16SCY domain-containing protein. (75 aa)
CCL14C-C motif chemokine. (109 aa)
CCL15C-C motif chemokine. (113 aa)
CCL23C-C motif chemokine. (137 aa)
CCL18C-C motif chemokine. (89 aa)
LOC100602388C-C motif chemokine. (92 aa)
CCL4C-C motif chemokine. (92 aa)
GBF1Golgi brefeldin A resistant guanine nucleotide exchange factor 1. (1859 aa)
DEFB130BUncharacterized protein. (79 aa)
LOC100604016DEFSN domain-containing protein. (64 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (233 aa)
PLA2G1BPhospholipase A(2). (148 aa)
DPEP1Dipeptidase; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (367 aa)
ALOX5Arachidonate 5-lipoxygenase. (655 aa)
TNFSF14Tumor necrosis factor ligand 1D; Belongs to the tumor necrosis factor family. (240 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (532 aa)
NINJ1Ninjurin 1. (152 aa)
C5Complement C5. (1676 aa)
CHGAChromogranin A. (460 aa)
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
PARVAParvin alpha. (345 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1. (589 aa)
BIN2Bridging integrator 2. (542 aa)
ANO6Anoctamin. (931 aa)
C5AR1Complement C5a receptor 1; Belongs to the G-protein coupled receptor 1 family. (350 aa)
CCR4C-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (360 aa)
ACKR2Atypical chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family. (384 aa)
CH25HCholesterol 25-hydroxylase; Belongs to the sterol desaturase family. (272 aa)
HRH1Histamine receptor H1; Belongs to the G-protein coupled receptor 1 family. (487 aa)
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (2098 aa)
SRP54Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (515 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (729 aa)
PREX1Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1537 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (901 aa)
ENGEndoglin. (658 aa)
TNFSF11Tumor necrosis factor ligand superfamily member. (317 aa)
LOC100607679SCY domain-containing protein. (98 aa)
IL16Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. (1330 aa)
LOC100599403PIPK domain-containing protein. (591 aa)
FCER1GUncharacterized protein. (112 aa)
PTNPleiotrophin. (172 aa)
VAV1Uncharacterized protein. (739 aa)
PDE4BPhosphodiesterase. (736 aa)
CCL25SCY domain-containing protein. (131 aa)
RAB13Uncharacterized protein. (203 aa)
ENSNLEP00000028912SCY domain-containing protein. (203 aa)
CTSGCathepsin G; Belongs to the peptidase S1 family. (255 aa)
LOC100583930C-C motif chemokine. (151 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
ENSNLEP00000032876Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (133 aa)
NCKAP1LNCK associated protein 1 like. (1109 aa)
ELMO2Engulfment and cell motility 2. (720 aa)
CXCL16C-X-C motif chemokine ligand 16. (265 aa)
SLAMF1Signaling lymphocytic activation molecule family member 1. (331 aa)
LEF1Lymphoid enhancer binding factor 1. (386 aa)
NUP85Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (659 aa)
ENSNLEP00000035662Uncharacterized protein. (69 aa)
CCL20C-C motif chemokine. (96 aa)
IL6RInterleukin 6 receptor. (420 aa)
RHOGRas homolog family member G. (191 aa)
ENSNLEP00000036155annotation not available (69 aa)
CXCR5C-X-C motif chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family. (372 aa)
TRPM4Uncharacterized protein. (1010 aa)
CXCR4C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (375 aa)
TRPM2LSDAT_euk domain-containing protein. (1224 aa)
LOC100595480SCY domain-containing protein. (103 aa)
ENSNLEP00000038427Uncharacterized protein. (305 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (140 aa)
S1PR1Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
CCL22C-C motif chemokine. (93 aa)
IL17RCIL17_R_N domain-containing protein. (549 aa)
ENSNLEP00000040637Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (166 aa)
ENSNLEP00000040732Uncharacterized protein. (68 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (827 aa)
PIP5K1APhosphatidylinositol-4-phosphate 5-kinase type 1 alpha. (562 aa)
FFAR2Free fatty acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (330 aa)
EDN3Uncharacterized protein. (211 aa)
ENSNLEP00000041829PIPK domain-containing protein. (329 aa)
CCR6C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (377 aa)
LOC100607085SCY domain-containing protein. (114 aa)
CX3CR1C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (386 aa)
AGTR1Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family. (394 aa)
PF4C-X-C motif chemokine. (106 aa)
CCR9C-C motif chemokine receptor 9; Belongs to the G-protein coupled receptor 1 family. (369 aa)
LOC100602058C-C motif chemokine. (92 aa)
LOC100591994C-C motif chemokine. (203 aa)
ENSNLEP00000044243IGv domain-containing protein. (199 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa)
PLECPlectin. (4280 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa)
ENSNLEP00000045002Uncharacterized protein. (69 aa)
TPBGTrophoblast glycoprotein. (384 aa)
PLXNB3Plexin B3. (1842 aa)
PIP5K1CPIPK domain-containing protein. (759 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
ENSNLEP00000046123Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (136 aa)
ITGA9Integrin subunit alpha 9; Belongs to the integrin alpha chain family. (1035 aa)
ENSNLEP00000046458Uncharacterized protein. (125 aa)
IL6Uncharacterized protein. (258 aa)
S100A8Protein S100; Belongs to the S-100 family. (93 aa)
ENSNLEP00000047342C-X-C motif chemokine. (94 aa)
LOC100595821SCY domain-containing protein. (92 aa)
HSD3B73Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (309 aa)
ARHGEF5DH domain-containing protein. (302 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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