STRINGSTRING
FKBPL FKBPL LOC100605962 LOC100605962 AR AR AGT AGT LHX1 LHX1 HOXB7 HOXB7 SIRT6 SIRT6 CAV3 CAV3 WNT2B WNT2B CTNNB1 CTNNB1 FGF7 FGF7 MAP3K13 MAP3K13 BMP7 BMP7 WNT5A WNT5A MAGED1 MAGED1 PDGFA PDGFA SOX8 SOX8 GREM1 GREM1 WNT2 WNT2 ABL1 ABL1 SFRP1 SFRP1 SMO SMO BMP4 BMP4 SNAI2 SNAI2 TGFB1 TGFB1 SIX1 SIX1 PAX2 PAX2 ESR1 ESR1 SIX2 SIX2 FGFR2 FGFR2 BTBD7 BTBD7 LGR4 LGR4 LRRK2 LRRK2 TACSTD2 TACSTD2 HGF HGF SOX9 SOX9 GDNF GDNF FGF10 FGF10 SULF1 SULF1 AGTR2 AGTR2 BCL11A BCL11A NOG NOG HOXD13 HOXD13 NTN4 NTN4 TNF TNF ENSNLEP00000049231 ENSNLEP00000049231
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FKBPLFKBP prolyl isomerase like. (349 aa)
LOC100605962Homeobox domain-containing protein. (193 aa)
ARUncharacterized protein. (392 aa)
AGTAngiotensinogen; Belongs to the serpin family. (485 aa)
LHX1LIM homeobox 1. (352 aa)
HOXB7Homeobox domain-containing protein. (107 aa)
SIRT6Deacetylase sirtuin-type domain-containing protein. (215 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (330 aa)
CTNNB1Catenin beta 1. (781 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (966 aa)
BMP7Bone morphogenetic protein 7. (430 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
MAGED1MAGE family member D1. (823 aa)
PDGFAPlatelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa)
SOX8SRY-box transcription factor 8. (446 aa)
GREM1CTCK domain-containing protein. (143 aa)
WNT2Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa)
ABL1Tyrosine-protein kinase. (1006 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (683 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
SIX1SIX homeobox 1. (284 aa)
PAX2Paired domain-containing protein. (385 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
SIX2SIX homeobox 2. (293 aa)
FGFR2Fibroblast growth factor receptor. (820 aa)
BTBD7BTB domain containing 7. (1133 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (929 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
TACSTD2Tumor associated calcium signal transducer 2. (323 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (729 aa)
SOX9SRY-box transcription factor 9. (510 aa)
GDNFTGF_BETA_2 domain-containing protein. (169 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
SULF1Sulfatase 1. (812 aa)
AGTR2Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. (363 aa)
BCL11ABAF chromatin remodeling complex subunit BCL11A. (838 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
HOXD13Homeobox D13. (306 aa)
NTN4Netrin 4. (623 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
ENSNLEP00000049231Uncharacterized protein. (351 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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