STRINGSTRING
ABCC1 ABCC1 MYLK MYLK BDKRB2 BDKRB2 PCGF2 PCGF2 GSKIP GSKIP NR4A2 NR4A2 EIF2S1 EIF2S1 EDN1 EDN1 ZFP36L1 ZFP36L1 FOXO1 FOXO1 GPX8 GPX8 MMP2 MMP2 PENK PENK ATP7A ATP7A MGMT MGMT PLA2R1 PLA2R1 STAU2 STAU2 RBM11 RBM11 RELB RELB MAPK3 MAPK3 TRPV4 TRPV4 SPHK1 SPHK1 NFE2L1 NFE2L1 RAD52 RAD52 NME8 NME8 FABP1 FABP1 EIF2AK3 EIF2AK3 TP53INP1 TP53INP1 SOD1 SOD1 STK39 STK39 MELK MELK NOS3 NOS3 PPIA PPIA AGAP3 AGAP3 MGST1 MGST1 CAPN3 CAPN3 GPX5 GPX5 PYROXD1 PYROXD1 SIGMAR1 SIGMAR1 PDCD10 PDCD10 PRDX5 PRDX5 UCP1 UCP1 SMPD3 SMPD3 DAPK1 DAPK1 KLF2 KLF2 NFAT5 NFAT5 ECT2 ECT2 EDNRA EDNRA PDK1 PDK1 PIK3CA PIK3CA PRKRA PRKRA PJVK PJVK TMEM161A TMEM161A ALDH3B1 ALDH3B1 ETV5 ETV5 IMPACT IMPACT OSER1 OSER1 MMP9 MMP9 STAU1 STAU1 PRKCD PRKCD ATM ATM XRCC5 XRCC5 APOA4 APOA4 BTK BTK SLC4A11 SLC4A11 PCNA PCNA SLC2A4 SLC2A4 MPO MPO STX2 STX2 ADNP2 ADNP2 MAPK7 MAPK7 ERRFI1 ERRFI1 RNF112 RNF112 PDK2 PDK2 MAPK13 MAPK13 ERMP1 ERMP1 ANKZF1 ANKZF1 SIRPA SIRPA PNPT1 PNPT1 PKD2 PKD2 ARNT ARNT PPARGC1B PPARGC1B ROMO1 ROMO1 PYCR1 PYCR1 CASP3 CASP3 SOD2 SOD2 RIPK1 RIPK1 FER FER ZNF277 ZNF277 ADPRHL2 ADPRHL2 NET1 NET1 TRPA1 TRPA1 ZC3H12A ZC3H12A STOX1 STOX1 ZNF622 ZNF622 WNT16 WNT16 EPO EPO GSR GSR SIRT1 SIRT1 BRF2 BRF2 KEAP1 KEAP1 FAS FAS SLC2A1 SLC2A1 ABL1 ABL1 PRDX2 PRDX2 SETX SETX AKR1B1 AKR1B1 RWDD1 RWDD1 ATG5 ATG5 PYCR2 PYCR2 CAB39 CAB39 PARP1 PARP1 SLC7A11 SLC7A11 STK25 STK25 ANKRD2 ANKRD2 G6PD G6PD ARG1 ARG1 SNCA SNCA SIRT2 SIRT2 PRKAA2 PRKAA2 JUN JUN PAX2 PAX2 RCSD1 RCSD1 TNFAIP3 TNFAIP3 ERN1 ERN1 DHRS2 DHRS2 ATF4 ATF4 AIFM1 AIFM1 RIPK3 RIPK3 PRKD1 PRKD1 VKORC1L1 VKORC1L1 TSPO TSPO STX4 STX4 WNK3 WNK3 PYCARD PYCARD CYP1B1 CYP1B1 FANCC FANCC AMBP AMBP ERCC6L2 ERCC6L2 EPAS1 EPAS1 PLEKHA1 PLEKHA1 IL18BP IL18BP DDIT3 DDIT3 STAT6 STAT6 ENDOG ENDOG ARNTL ARNTL CAT CAT PRR5L PRR5L LRRK2 LRRK2 GPX7 GPX7 PTGS2 PTGS2 ATG7 ATG7 PINK1 PINK1 SESN2 SESN2 HDAC6 HDAC6 SLC11A2 SLC11A2 CHUK CHUK ENSNLEP00000026081 ENSNLEP00000026081 MAPK10 MAPK10 ENSNLEP00000026488 ENSNLEP00000026488 OXSR1 OXSR1 MAPK1 MAPK1 MPV17 MPV17 AKT1 AKT1 ARHGEF2 ARHGEF2 DDX3X DDX3X SRXN1 SRXN1 PPIF PPIF CPEB2 CPEB2 EZH2 EZH2 FXN FXN ENSNLEP00000029188 ENSNLEP00000029188 ENSNLEP00000029247 ENSNLEP00000029247 SLC8A1 SLC8A1 LOC100605818 LOC100605818 RPTOR RPTOR YBX3 YBX3 LOC100593245 LOC100593245 ENSNLEP00000031088 ENSNLEP00000031088 MAPK9 MAPK9 BNIP3 BNIP3 NUDT2 NUDT2 ATP13A2 ATP13A2 ARL6IP5 ARL6IP5 CAV1 CAV1 ENSNLEP00000032236 ENSNLEP00000032236 MSRA MSRA ENSNLEP00000032876 ENSNLEP00000032876 FANCD2 FANCD2 TPM1 TPM1 ATF2 ATF2 MTOR MTOR SLC25A24 SLC25A24 PRKAA1 PRKAA1 ENSNLEP00000034159 ENSNLEP00000034159 ENSNLEP00000034296 ENSNLEP00000034296 MAP1LC3A MAP1LC3A CCS CCS ENSNLEP00000035216 ENSNLEP00000035216 LOC100596299 LOC100596299 ENSNLEP00000035773 ENSNLEP00000035773 EGFR EGFR STK24 STK24 SOD3 SOD3 RELA RELA BCL2 BCL2 LRRC8E LRRC8E MLST8 MLST8 PPARG PPARG ENSNLEP00000037399 ENSNLEP00000037399 ENSNLEP00000037793 ENSNLEP00000037793 TRPM2 TRPM2 ENSNLEP00000038260 ENSNLEP00000038260 HDAC2 HDAC2 ENSNLEP00000038691 ENSNLEP00000038691 OXR1 OXR1 LOC100601157 LOC100601157 PRODH PRODH HSF1 HSF1 HTRA2 HTRA2 NQO1 NQO1 NOX1 NOX1 ENSNLEP00000040637 ENSNLEP00000040637 ENSNLEP00000040692 ENSNLEP00000040692 VRK2 VRK2 FYN FYN RHOB RHOB PPARGC1A PPARGC1A CAMKK2 CAMKK2 NFE2L2 NFE2L2 XBP1 XBP1 ENSNLEP00000043248 ENSNLEP00000043248 MGAT3 MGAT3 PARK7 PARK7 SCN2A SCN2A SIN3A SIN3A SELENOS SELENOS PTPRK PTPRK CASP1 CASP1 PLEC PLEC SLC1A1 SLC1A1 CD36 CD36 ATP2A2 ATP2A2 ENSNLEP00000045860 ENSNLEP00000045860 LRRC8C LRRC8C MAPK8 MAPK8 ENSNLEP00000046123 ENSNLEP00000046123 LONP1 LONP1 PML PML CHD6 CHD6 LOC100584186 LOC100584186 PRDX1 PRDX1 IL6 IL6 CRYGD CRYGD FOS FOS AKR1C3 AKR1C3 ENSNLEP00000047861 ENSNLEP00000047861 MAP3K5 MAP3K5 RPS3 RPS3 PXN PXN AXL AXL AIF1 AIF1 SRC SRC HIF1A HIF1A SLC12A6 SLC12A6 ENSNLEP00000048874 ENSNLEP00000048874 AQP1 AQP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABCC1Uncharacterized protein. (1058 aa)
MYLKMyosin light chain kinase. (1793 aa)
BDKRB2Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. (386 aa)
PCGF2RING-type domain-containing protein. (274 aa)
GSKIPGSK3B interacting protein. (144 aa)
NR4A2Nuclear receptor subfamily 4 group A member 2. (598 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit alpha. (315 aa)
EDN1Endothelin 1. (211 aa)
ZFP36L1ZFP36 ring finger protein like 1. (338 aa)
FOXO1Forkhead box O1. (652 aa)
GPX8Glutathione peroxidase; Belongs to the glutathione peroxidase family. (209 aa)
MMP2Matrix metallopeptidase 2. (647 aa)
PENKProenkephalin. (267 aa)
ATP7AATPase copper transporting alpha. (1460 aa)
MGMTO-6-methylguanine-DNA methyltransferase. (238 aa)
PLA2R1Phospholipase A2 receptor 1. (1463 aa)
STAU2Staufen double-stranded RNA binding protein 2. (570 aa)
RBM11RNA binding motif protein 11. (281 aa)
RELBRELB proto-oncogene, NF-kB subunit. (586 aa)
MAPK3Mitogen-activated protein kinase. (278 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (846 aa)
SPHK1DAGKc domain-containing protein. (398 aa)
NFE2L1Nuclear factor, erythroid 2 like 1. (757 aa)
RAD52RAD52 homolog, DNA repair protein. (420 aa)
NME8NME/NM23 family member 8. (588 aa)
FABP1Fatty acid binding protein 1. (127 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1120 aa)
TP53INP1Tumor protein p53 inducible nuclear protein 1. (240 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
STK39Serine/threonine kinase 39. (507 aa)
MELKNon-specific serine/threonine protein kinase. (651 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1128 aa)
PPIAPeptidyl-prolyl cis-trans isomerase A, N-terminally processed; PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding; Belongs to the cyclophilin-type PPIase family. PPIase A subfamily. (165 aa)
AGAP3ArfGAP with GTPase domain, ankyrin repeat and PH domain 3. (742 aa)
MGST1Microsomal glutathione S-transferase 1. (155 aa)
CAPN3Calpain 3; Belongs to the peptidase C2 family. (837 aa)
GPX5Glutathione peroxidase; Belongs to the glutathione peroxidase family. (221 aa)
PYROXD1Pyridine nucleotide-disulphide oxidoreductase domain 1. (500 aa)
SIGMAR1Sigma non-opioid intracellular receptor 1. (223 aa)
PDCD10Programmed cell death 10. (212 aa)
PRDX5Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (158 aa)
UCP1Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (655 aa)
DAPK1Death associated protein kinase 1. (1430 aa)
KLF2Kruppel like factor 2. (355 aa)
NFAT5Nuclear factor of activated T cells 5. (1547 aa)
ECT2Epithelial cell transforming 2. (914 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
PDK1Protein-serine/threonine kinase. (456 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
PRKRAUncharacterized protein. (288 aa)
PJVKPejvakin. (352 aa)
TMEM161AUncharacterized protein. (455 aa)
ALDH3B1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (485 aa)
ETV5ETS variant 5. (510 aa)
IMPACTImpact RWD domain protein. (320 aa)
OSER1Oxidative stress responsive serine rich 1. (292 aa)
MMP9Matrix metallopeptidase 9. (692 aa)
STAU1Staufen double-stranded RNA binding protein 1. (577 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3055 aa)
XRCC5X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (732 aa)
APOA4Apolipoprotein A4. (392 aa)
BTKTyrosine-protein kinase. (659 aa)
SLC4A11Solute carrier family 4 member 11. (890 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
SLC2A4Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (481 aa)
MPOMyeloperoxidase. (745 aa)
STX2Syntaxin 2; Belongs to the syntaxin family. (287 aa)
ADNP2ADNP homeobox 2. (1125 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
ERRFI1ERBB receptor feedback inhibitor 1. (462 aa)
RNF112Ring finger protein 112. (643 aa)
PDK2Protein-serine/threonine kinase. (415 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
ERMP1Endoplasmic reticulum metallopeptidase 1. (798 aa)
ANKZF1Ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1. (727 aa)
SIRPAUncharacterized protein. (486 aa)
PNPT1Polyribonucleotide nucleotidyltransferase 1. (772 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (921 aa)
ARNTAryl hydrocarbon receptor nuclear translocator. (789 aa)
PPARGC1BPPARG coactivator 1 beta. (1013 aa)
ROMO1Reactive oxygen species modulator 1. (79 aa)
PYCR1Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (319 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (277 aa)
SOD2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (222 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (671 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
ZNF277Zinc finger protein 277. (442 aa)
ADPRHL2ADP-ribosylhydrolase like 2. (364 aa)
NET1Neuroepithelial cell transforming 1. (596 aa)
TRPA1Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1094 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (560 aa)
STOX1Storkhead box 1. (937 aa)
ZNF622Zinc finger protein 622. (477 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (193 aa)
GSRGlutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (522 aa)
SIRT1Sirtuin 1. (734 aa)
BRF2TFIIB-type domain-containing protein. (356 aa)
KEAP1BTB domain-containing protein. (395 aa)
FASFas cell surface death receptor. (335 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (462 aa)
ABL1Tyrosine-protein kinase. (1006 aa)
PRDX2Peroxiredoxin 2. (163 aa)
SETXSenataxin. (2576 aa)
AKR1B1Aldo-keto reductase family 1 member B. (316 aa)
RWDD1RWD domain containing 1. (243 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
PYCR2Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (320 aa)
CAB39Calcium binding protein 39. (341 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (948 aa)
SLC7A11Solute carrier family 7 member 11. (500 aa)
STK25Serine/threonine kinase 25. (416 aa)
ANKRD2Ankyrin repeat domain 2. (360 aa)
G6PDUncharacterized protein. (452 aa)
ARG1Arginase. (322 aa)
SNCAAlpha-synuclein; Belongs to the synuclein family. (140 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (386 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
JUNBZIP domain-containing protein; Belongs to the bZIP family. (305 aa)
PAX2Paired domain-containing protein. (385 aa)
RCSD1RCSD domain containing 1. (413 aa)
TNFAIP3TNF alpha induced protein 3. (790 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (977 aa)
DHRS2Dehydrogenase/reductase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (300 aa)
ATF4BZIP domain-containing protein. (351 aa)
AIFM1Apoptosis inducing factor mitochondria associated 1. (613 aa)
RIPK3Receptor interacting serine/threonine kinase 3. (506 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (832 aa)
VKORC1L1VKc domain-containing protein. (132 aa)
TSPOTranslocator protein. (169 aa)
STX4Syntaxin 4; Belongs to the syntaxin family. (297 aa)
WNK3WNK lysine deficient protein kinase 3. (1800 aa)
PYCARDPYD and CARD domain containing. (195 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa)
FANCCFanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1. (526 aa)
AMBPAlpha-1-microglobulin/bikunin precursor. (312 aa)
ERCC6L2ERCC excision repair 6 like 2. (712 aa)
EPAS1Endothelial PAS domain protein 1. (869 aa)
PLEKHA1Pleckstrin homology domain containing A1. (404 aa)
IL18BPInterleukin 18 binding protein. (194 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa)
STAT6Signal transducer and activator of transcription. (842 aa)
ENDOGEndonuclease. (278 aa)
ARNTLAryl hydrocarbon receptor nuclear translocator like. (620 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa)
PRR5LProline rich 5 like. (368 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
GPX7Glutathione peroxidase; Belongs to the glutathione peroxidase family. (187 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
ATG7Autophagy related 7. (672 aa)
PINK1Protein kinase domain-containing protein. (563 aa)
SESN2Sestrin 2. (470 aa)
HDAC6Uncharacterized protein. (146 aa)
SLC11A2Solute carrier family 11 member 2. (568 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (743 aa)
ENSNLEP00000026081Protein kinase domain-containing protein. (407 aa)
MAPK10Mitogen-activated protein kinase. (550 aa)
ENSNLEP00000026488Aldo_ket_red domain-containing protein. (282 aa)
OXSR1Oxidative stress responsive kinase 1. (530 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (341 aa)
MPV17Mitochondrial inner membrane protein MPV17; Belongs to the peroxisomal membrane protein PXMP2/4 family. (191 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa)
ARHGEF2Rho/Rac guanine nucleotide exchange factor 2. (1031 aa)
DDX3XDEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (704 aa)
SRXN1Sulfiredoxin. (161 aa)
PPIFPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (205 aa)
CPEB2Uncharacterized protein. (500 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (746 aa)
FXNUncharacterized protein. (196 aa)
ENSNLEP00000029188Uncharacterized protein. (60 aa)
ENSNLEP00000029247Uncharacterized protein. (138 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (972 aa)
LOC100605818BZIP domain-containing protein. (347 aa)
RPTORRegulatory associated protein of MTOR complex 1. (1318 aa)
YBX3Y-box binding protein 3. (344 aa)
LOC100593245Uncharacterized protein; Belongs to the beta/gamma-crystallin family. (176 aa)
ENSNLEP00000031088Protein kinase domain-containing protein. (557 aa)
MAPK9Mitogen-activated protein kinase. (382 aa)
BNIP3Uncharacterized protein. (231 aa)
NUDT2Nudix hydrolase 2. (147 aa)
ATP13A2Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1012 aa)
ARL6IP5PRA1 family protein. (188 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
ENSNLEP00000032236Uncharacterized protein. (109 aa)
MSRAMethionine sulfoxide reductase A. (235 aa)
ENSNLEP00000032876Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (133 aa)
FANCD2FA complementation group D2. (1427 aa)
TPM1Uncharacterized protein; Belongs to the tropomyosin family. (326 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2578 aa)
SLC25A24Solute carrier family 25 member 24; Belongs to the mitochondrial carrier (TC 2.A.29) family. (477 aa)
PRKAA1Non-specific serine/threonine protein kinase. (574 aa)
ENSNLEP00000034159Uncharacterized protein. (453 aa)
ENSNLEP00000034296DJ-1_PfpI domain-containing protein. (133 aa)
MAP1LC3AMicrotubule associated protein 1 light chain 3 alpha. (124 aa)
CCSCopper chaperone for superoxide dismutase. (274 aa)
ENSNLEP00000035216Uncharacterized protein. (132 aa)
LOC100596299Coiled-coil-helix-coiled-coil-helix domain containing 2. (151 aa)
ENSNLEP00000035773Aldo_ket_red domain-containing protein. (273 aa)
EGFRReceptor protein-tyrosine kinase. (1206 aa)
STK24Serine/threonine kinase 24. (443 aa)
SOD3Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (240 aa)
RELARELA proto-oncogene, NF-kB subunit. (551 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
LRRC8EPannexin_like domain-containing protein. (408 aa)
MLST8MTOR associated protein, LST8 homolog. (326 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
ENSNLEP00000037399S1 motif domain-containing protein. (687 aa)
ENSNLEP00000037793Uncharacterized protein. (122 aa)
TRPM2LSDAT_euk domain-containing protein. (1224 aa)
ENSNLEP00000038260Uncharacterized protein. (335 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (533 aa)
ENSNLEP000000386911-cysPrx_C domain-containing protein. (97 aa)
OXR1Oxidation resistance 1. (875 aa)
LOC100601157VKc domain-containing protein. (136 aa)
PRODHProline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (595 aa)
HSF1HSF_DOMAIN domain-containing protein. (272 aa)
HTRA2HtrA serine peptidase 2. (458 aa)
NQO1NAD(P)H quinone dehydrogenase 1. (261 aa)
NOX1NADPH oxidase 1. (564 aa)
ENSNLEP00000040637Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (166 aa)
ENSNLEP00000040692Uncharacterized protein. (441 aa)
VRK2VRK serine/threonine kinase 2. (509 aa)
FYNTyrosine-protein kinase. (537 aa)
RHOBRas homolog family member B. (196 aa)
PPARGC1APPARG coactivator 1 alpha. (801 aa)
CAMKK2Calcium/calmodulin dependent protein kinase kinase 2. (591 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (607 aa)
XBP1BZIP domain-containing protein. (376 aa)
ENSNLEP00000043248Uncharacterized protein. (285 aa)
MGAT3Mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase. (511 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
SCN2ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1939 aa)
SIN3ASIN3 transcription regulator family member A. (1250 aa)
SELENOSUncharacterized protein. (218 aa)
PTPRKProtein tyrosine phosphatase receptor type K. (1416 aa)
CASP1Caspase 1; Belongs to the peptidase C14A family. (404 aa)
PLECPlectin. (4280 aa)
SLC1A1Amino acid transporter. (457 aa)
CD36CD36 molecule; Belongs to the CD36 family. (433 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
ENSNLEP00000045860Uncharacterized protein. (64 aa)
LRRC8CLeucine rich repeat containing 8 VRAC subunit C. (803 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
ENSNLEP00000046123Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (136 aa)
LONP1Lon proteolytic domain-containing protein; Belongs to the peptidase S16 family. (722 aa)
PMLUncharacterized protein. (873 aa)
CHD6Chromodomain helicase DNA binding protein 6. (2696 aa)
LOC100584186KH type-2 domain-containing protein. (260 aa)
PRDX1Peroxiredoxin 1. (199 aa)
IL6Uncharacterized protein. (258 aa)
CRYGDUncharacterized protein; Belongs to the beta/gamma-crystallin family. (174 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
AKR1C3Aldo-keto reductase family 1 member C3. (323 aa)
ENSNLEP00000047861annotation not available (282 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1347 aa)
RPS3Ribosomal_S3_C domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (190 aa)
PXNUncharacterized protein. (1078 aa)
AXLReceptor protein-tyrosine kinase. (860 aa)
AIF1Allograft inflammatory factor 1. (161 aa)
SRCTyrosine-protein kinase. (537 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (850 aa)
SLC12A6Solute carrier family 12 member 6. (1150 aa)
ENSNLEP00000048874Uncharacterized protein. (178 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (269 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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