64 items (Nomascus leucogenys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	OSER1	Oxidative stress responsive serine rich 1. (292 aa)
	IMPACT	Impact RWD domain protein. (320 aa)
	ECT2	Epithelial cell transforming 2. (914 aa)
	KLF2	Kruppel like factor 2. (355 aa)
	SMPD3	Sphingomyelin phosphodiesterase 3. (655 aa)
	PDCD10	Programmed cell death 10. (212 aa)
	SIGMAR1	Sigma non-opioid intracellular receptor 1. (223 aa)
	FABP1	Fatty acid binding protein 1. (127 aa)
	SPHK1	DAGKc domain-containing protein. (398 aa)
	EDN1	Endothelin 1. (211 aa)
	PCGF2	RING-type domain-containing protein. (274 aa)
	MAPK7	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
	AQP1	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (269 aa)
	ENSNLEP00000048874	Uncharacterized protein. (178 aa)
	SRC	Tyrosine-protein kinase. (537 aa)
	AXL	Receptor protein-tyrosine kinase. (860 aa)
	RPS3	Ribosomal_S3_C domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (190 aa)
	MAP3K5	Mitogen-activated protein kinase kinase kinase 5. (1347 aa)
	IL6	Uncharacterized protein. (258 aa)
	LOC100584186	KH type-2 domain-containing protein. (260 aa)
	ENSNLEP00000045860	Uncharacterized protein. (64 aa)
	PARK7	Parkinsonism associated deglycase. (189 aa)
	NFE2L2	Nuclear factor, erythroid 2 like 2. (607 aa)
	RHOB	Ras homolog family member B. (196 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	HSF1	HSF_DOMAIN domain-containing protein. (272 aa)
	HDAC2	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (533 aa)
	TRPM2	LSDAT_euk domain-containing protein. (1224 aa)
	ENSNLEP00000037793	Uncharacterized protein. (122 aa)
	RELA	RELA proto-oncogene, NF-kB subunit. (551 aa)
	MAP1LC3A	Microtubule associated protein 1 light chain 3 alpha. (124 aa)
	ENSNLEP00000034296	DJ-1_PfpI domain-containing protein. (133 aa)
	ENSNLEP00000032236	Uncharacterized protein. (109 aa)
	BNIP3	Uncharacterized protein. (231 aa)
	ENSNLEP00000029188	Uncharacterized protein. (60 aa)
	FXN	Uncharacterized protein. (196 aa)
	EZH2	Enhancer of zeste 2 polycomb repressive complex 2 subunit. (746 aa)
	PPIF	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (205 aa)
	HDAC6	Uncharacterized protein. (146 aa)
	CAT	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa)
	STAT6	Signal transducer and activator of transcription. (842 aa)
	IL18BP	Interleukin 18 binding protein. (194 aa)
	PLEKHA1	Pleckstrin homology domain containing A1. (404 aa)
	CYP1B1	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa)
	RIPK3	Receptor interacting serine/threonine kinase 3. (506 aa)
	AIFM1	Apoptosis inducing factor mitochondria associated 1. (613 aa)
	ERN1	Endoplasmic reticulum to nucleus signaling 1. (977 aa)
	TNFAIP3	TNF alpha induced protein 3. (790 aa)
	PAX2	Paired domain-containing protein. (385 aa)
	ARG1	Arginase. (322 aa)
	STK25	Serine/threonine kinase 25. (416 aa)
	SETX	Senataxin. (2576 aa)
	ABL1	Tyrosine-protein kinase. (1006 aa)
	SIRT1	Sirtuin 1. (734 aa)
	TRPA1	Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1094 aa)
	NET1	Neuroepithelial cell transforming 1. (596 aa)
	ZNF277	Zinc finger protein 277. (442 aa)
	RIPK1	Receptor interacting serine/threonine kinase 1. (671 aa)
	SIRPA	Uncharacterized protein. (486 aa)
	ANKZF1	Ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1. (727 aa)
	MAPK13	Mitogen-activated protein kinase. (365 aa)
	RNF112	Ring finger protein 112. (643 aa)
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	PRKCD	Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)

Your Current Organism:

Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL1	EZH2	ENSNLEP00000015256	ENSNLEP00000028936	Tyrosine-protein kinase.	Enhancer of zeste 2 polycomb repressive complex 2 subunit.	0.486
ABL1	IL6	ENSNLEP00000015256	ENSNLEP00000047139	Tyrosine-protein kinase.	Uncharacterized protein.	0.421
ABL1	MAPK13	ENSNLEP00000015256	ENSNLEP00000010961	Tyrosine-protein kinase.	Mitogen-activated protein kinase.	0.449
ABL1	MAPK7	ENSNLEP00000015256	ENSNLEP00000010710	Tyrosine-protein kinase.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.422
ABL1	PRKCD	ENSNLEP00000015256	ENSNLEP00000008796	Tyrosine-protein kinase.	Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.434
ABL1	SRC	ENSNLEP00000015256	ENSNLEP00000048569	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.459
ARG1	IL6	ENSNLEP00000017426	ENSNLEP00000047139	Arginase.	Uncharacterized protein.	0.613
ARG1	STAT6	ENSNLEP00000017426	ENSNLEP00000021135	Arginase.	Signal transducer and activator of transcription.	0.537
AXL	TNFAIP3	ENSNLEP00000048120	ENSNLEP00000018156	Receptor protein-tyrosine kinase.	TNF alpha induced protein 3.	0.435
BNIP3	MAP1LC3A	ENSNLEP00000031443	ENSNLEP00000034449	Uncharacterized protein.	Microtubule associated protein 1 light chain 3 alpha.	0.490
CAT	ENSNLEP00000029188	ENSNLEP00000021774	ENSNLEP00000029188	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Uncharacterized protein.	0.567
CAT	ENSNLEP00000034296	ENSNLEP00000021774	ENSNLEP00000034296	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	DJ-1_PfpI domain-containing protein.	0.567
CAT	PARK7	ENSNLEP00000021774	ENSNLEP00000043391	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	Parkinsonism associated deglycase.	0.567
ECT2	RHOB	ENSNLEP00000006789	ENSNLEP00000041096	Epithelial cell transforming 2.	Ras homolog family member B.	0.690
EDN1	IL6	ENSNLEP00000000874	ENSNLEP00000047139	Endothelin 1.	Uncharacterized protein.	0.544
EDN1	SRC	ENSNLEP00000000874	ENSNLEP00000048569	Endothelin 1.	Tyrosine-protein kinase.	0.562
ENSNLEP00000029188	CAT	ENSNLEP00000029188	ENSNLEP00000021774	Uncharacterized protein.	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.	0.567
ENSNLEP00000029188	HDAC6	ENSNLEP00000029188	ENSNLEP00000024481	Uncharacterized protein.	Uncharacterized protein.	0.512
ENSNLEP00000029188	MAP3K5	ENSNLEP00000029188	ENSNLEP00000047890	Uncharacterized protein.	Mitogen-activated protein kinase kinase kinase 5.	0.587
ENSNLEP00000029188	NFE2L2	ENSNLEP00000029188	ENSNLEP00000042804	Uncharacterized protein.	Nuclear factor, erythroid 2 like 2.	0.422

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