STRINGSTRING
FGF21 FGF21 CD9 CD9 ITGB2 ITGB2 LOC100599005 LOC100599005 SYK SYK CASR CASR CES1 CES1 CD36 CD36 CD81 CD81 LDLR LDLR SOCS5 SOCS5 PPARG PPARG ITGB1 ITGB1 FCER1G FCER1G ABCA1 ABCA1 SREBF2 SREBF2 NPC1 NPC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FGF21Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
CD9Tetraspanin. (228 aa)
ITGB2Integrin beta. (762 aa)
LOC100599005Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (567 aa)
SYKTyrosine-protein kinase. (532 aa)
CASRCalcium sensing receptor. (1088 aa)
CES1Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (570 aa)
CD36CD36 molecule; Belongs to the CD36 family. (433 aa)
CD81Tetraspanin. (274 aa)
LDLRUncharacterized protein. (839 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
FCER1GUncharacterized protein. (112 aa)
ABCA1ATP binding cassette subfamily A member 1. (2254 aa)
SREBF2Sterol regulatory element binding transcription factor 2. (1067 aa)
NPC1NPC intracellular cholesterol transporter 1. (1221 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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