42 items (Nomascus leucogenys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SMYD3	SET and MYND domain containing 3. (369 aa)
	EDN1	Endothelin 1. (211 aa)
	RPS6KB1	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (513 aa)
	CYP1B1	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa)
	AQP1	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (269 aa)
	FBXO32	F-box protein 32. (371 aa)
	IGF1R	Tyrosine-protein kinase receptor. (1199 aa)
	ENSNLEP00000042382	Uncharacterized protein. (425 aa)
	ENSNLEP00000041025	Uncharacterized protein. (381 aa)
	ENSNLEP00000037553	Uncharacterized protein. (100 aa)
	ENSNLEP00000034094	Uncharacterized protein. (313 aa)
	LOC101175914	Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (180 aa)
	ENSNLEP00000029616	RGS domain-containing protein. (169 aa)
	GDNF	TGF_BETA_2 domain-containing protein. (169 aa)
	ENSNLEP00000028114	Uncharacterized protein. (405 aa)
	CPS1	Carbamoyl-phosphate synthase 1. (1506 aa)
	ENSNLEP00000027205	Uncharacterized protein. (353 aa)
	ENSNLEP00000026090	3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (258 aa)
	ENSNLEP00000025620	Uncharacterized protein. (154 aa)
	SERPINF1	Serpin family F member 1; Belongs to the serpin family. (366 aa)
	PAPPA	Pappalysin 1. (1627 aa)
	DDIT4	DNA damage inducible transcript 4. (232 aa)
	PCK2	Phosphoenolpyruvate carboxykinase 2, mitochondrial. (575 aa)
	AXIN2	DIX domain-containing protein. (294 aa)
	ARG1	Arginase. (322 aa)
	EIF4E	Uncharacterized protein. (212 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	ASS1	Uncharacterized protein. (412 aa)
	SRD5A1	3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (259 aa)
	TFAP4	Transcription factor AP-4. (338 aa)
	PTAFR	Platelet activating factor receptor; Belongs to the G-protein coupled receptor 1 family. (342 aa)
	JAK2	Tyrosine-protein kinase. (1132 aa)
	ERRFI1	ERBB receptor feedback inhibitor 1. (462 aa)
	POR	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (680 aa)
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	CASP9	Caspase 9; Belongs to the peptidase C14A family. (426 aa)
	CLDN1	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
	MSTN	Myostatin. (376 aa)
	USP8	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1117 aa)
	TAT	Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. (454 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
	GHSR	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)

Your Current Organism:

Nomascus leucogenys

NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARG1	ASS1	ENSNLEP00000017426	ENSNLEP00000015204	Arginase.	Uncharacterized protein.	0.467
ARG1	CPS1	ENSNLEP00000017426	ENSNLEP00000027977	Arginase.	Carbamoyl-phosphate synthase 1.	0.561
ARG1	ENSNLEP00000042382	ENSNLEP00000017426	ENSNLEP00000042382	Arginase.	Uncharacterized protein.	0.467
ARG1	TGFB1	ENSNLEP00000017426	ENSNLEP00000016659	Arginase.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.457
ASS1	ARG1	ENSNLEP00000015204	ENSNLEP00000017426	Uncharacterized protein.	Arginase.	0.467
ASS1	CPS1	ENSNLEP00000015204	ENSNLEP00000027977	Uncharacterized protein.	Carbamoyl-phosphate synthase 1.	0.968
AXIN2	ENSNLEP00000029616	ENSNLEP00000018040	ENSNLEP00000029616	DIX domain-containing protein.	RGS domain-containing protein.	0.887
CASP9	PIK3CA	ENSNLEP00000009264	ENSNLEP00000006936	Caspase 9; Belongs to the peptidase C14A family.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.402
CPS1	ARG1	ENSNLEP00000027977	ENSNLEP00000017426	Carbamoyl-phosphate synthase 1.	Arginase.	0.561
CPS1	ASS1	ENSNLEP00000027977	ENSNLEP00000015204	Carbamoyl-phosphate synthase 1.	Uncharacterized protein.	0.968
CPS1	ENSNLEP00000025620	ENSNLEP00000027977	ENSNLEP00000025620	Carbamoyl-phosphate synthase 1.	Uncharacterized protein.	0.665
CPS1	ENSNLEP00000027205	ENSNLEP00000027977	ENSNLEP00000027205	Carbamoyl-phosphate synthase 1.	Uncharacterized protein.	0.676
CPS1	ENSNLEP00000028114	ENSNLEP00000027977	ENSNLEP00000028114	Carbamoyl-phosphate synthase 1.	Uncharacterized protein.	0.698
CPS1	ENSNLEP00000034094	ENSNLEP00000027977	ENSNLEP00000034094	Carbamoyl-phosphate synthase 1.	Uncharacterized protein.	0.688
CPS1	ENSNLEP00000037553	ENSNLEP00000027977	ENSNLEP00000037553	Carbamoyl-phosphate synthase 1.	Uncharacterized protein.	0.665
CPS1	ENSNLEP00000041025	ENSNLEP00000027977	ENSNLEP00000041025	Carbamoyl-phosphate synthase 1.	Uncharacterized protein.	0.679
CPS1	ENSNLEP00000042382	ENSNLEP00000027977	ENSNLEP00000042382	Carbamoyl-phosphate synthase 1.	Uncharacterized protein.	0.837
CPS1	TAT	ENSNLEP00000027977	ENSNLEP00000007009	Carbamoyl-phosphate synthase 1.	Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.	0.442
DDIT4	EIF4E	ENSNLEP00000019925	ENSNLEP00000016993	DNA damage inducible transcript 4.	Uncharacterized protein.	0.457
DDIT4	RPS6KB1	ENSNLEP00000019925	ENSNLEP00000000805	DNA damage inducible transcript 4.	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	0.435

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