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PRODH2 PRODH2 KDM1B KDM1B ACOXL ACOXL SQLE SQLE SQOR SQOR AGPS AGPS TXNRD1 TXNRD1 CRY1 CRY1 DAO DAO ACOX2 ACOX2 D2HGDH D2HGDH MICAL3 MICAL3 NDOR1 NDOR1 MTRR MTRR ACOX3 ACOX3 ERO1A ERO1A MICAL1 MICAL1 DDO DDO MMACHC MMACHC DHCR24 DHCR24 STEAP4 STEAP4 AIFM1 AIFM1 COQ6 COQ6 CYB5R2 CYB5R2 MICAL2 MICAL2 MICALCL MICALCL CRY2 CRY2 ERO1B ERO1B KMO KMO AOX1 AOX1 ACOX1 ACOX1 LOC100583419 LOC100583419 PCYOX1 PCYOX1 PRODH PRODH XDH XDH LDHD LDHD CYB5R1 CYB5R1 MTHFR MTHFR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRODH2Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (536 aa)
KDM1BUncharacterized protein. (822 aa)
ACOXLAcyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (580 aa)
SQLESqualene epoxidase. (574 aa)
SQORUncharacterized protein. (441 aa)
AGPSAlkylglycerone-phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids; Belongs to the FAD-binding oxidoreductase/transferase type 4 family. (656 aa)
TXNRD1Thioredoxin reductase 1. (647 aa)
CRY1Cryptochrome circadian regulator 1. (586 aa)
DAOD-amino acid oxidase. (314 aa)
ACOX2Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (681 aa)
D2HGDHD-2-hydroxyglutarate dehydrogenase. (475 aa)
MICAL3Microtubule associated monooxygenase, calponin and LIM domain containing 3. (2002 aa)
NDOR1NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe/S cluster of CIAPIN1. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (595 aa)
MTRR5-methyltetrahydrofolate-homocysteine methyltransferase reductase. (698 aa)
ACOX3Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (690 aa)
ERO1AEndoplasmic reticulum oxidoreductase 1 alpha. (468 aa)
MICAL1Microtubule associated monooxygenase, calponin and LIM domain containing 1. (1086 aa)
DDOD-aspartate oxidase. (369 aa)
MMACHCMetabolism of cobalamin associated C. (281 aa)
DHCR2424-dehydrocholesterol reductase. (514 aa)
STEAP4STEAP4 metalloreductase. (459 aa)
AIFM1Apoptosis inducing factor mitochondria associated 1. (613 aa)
COQ6Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (468 aa)
CYB5R2NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (276 aa)
MICAL2Microtubule associated monooxygenase, calponin and LIM domain containing 2. (1124 aa)
MICALCLBMERB domain-containing protein. (420 aa)
CRY2Photolyase/cryptochrome alpha/beta domain-containing protein. (523 aa)
ERO1BEndoplasmic reticulum oxidoreductase 1 beta. (467 aa)
KMOKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. (486 aa)
AOX1Aldehyde oxidase 1. (1338 aa)
ACOX1Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (661 aa)
LOC100583419FAD-binding PCMH-type domain-containing protein. (1085 aa)
PCYOX1Prenylcysteine oxidase 1. (505 aa)
PRODHProline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (595 aa)
XDHXanthine dehydrogenase. (1271 aa)
LDHDFAD-binding PCMH-type domain-containing protein. (539 aa)
CYB5R1NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (305 aa)
MTHFRMethylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (654 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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