STRINGSTRING
OGG1 OGG1 CDADC1 CDADC1 CAD CAD ACPP ACPP ERH ERH UNG UNG UPP2 UPP2 UMPS UMPS NT5C NT5C TET3 TET3 ENSNLEP00000049179 ENSNLEP00000049179 TK2 TK2 LOC100582337 LOC100582337 CMPK2 CMPK2 APOBEC3C APOBEC3C UPB1 UPB1 ENTPD4 ENTPD4 UPRT UPRT ENTPD7 ENTPD7 ALDH6A1 ALDH6A1 UNG-2 UNG-2 ENSNLEP00000041001 ENSNLEP00000041001 TKTL2 TKTL2 ENSNLEP00000036501 ENSNLEP00000036501 NME6 NME6 DCK DCK MTOR MTOR DHODH DHODH TPK1 TPK1 ENSNLEP00000031350 ENSNLEP00000031350 ENSNLEP00000030795 ENSNLEP00000030795 AICDA AICDA ENSNLEP00000030516 ENSNLEP00000030516 NME1-NME2 NME1-NME2 LOC100604176 LOC100604176 DCTD DCTD APOBEC3D APOBEC3D CPS1 CPS1 MAPK1 MAPK1 NME9 NME9 SMUG1 SMUG1 CMPK1 CMPK1 ENTPD5 ENTPD5 ZBTB49 ZBTB49 DCTPP1 DCTPP1 NT5C3A NT5C3A APOBEC3H APOBEC3H APOBEC3A APOBEC3A THTPA THTPA SLC19A2 SLC19A2 NME7 NME7 UCK2 UCK2 TBPL1 TBPL1 ENPP3 ENPP3 TKTL1 TKTL1 G1RT41_NOMLE G1RT41_NOMLE SLC19A3 SLC19A3 TET2 TET2 NEIL1 NEIL1 UCK1 UCK1 CTPS1 CTPS1 TET1 TET1 DPYD DPYD LOC100596171 LOC100596171 UCKL1 UCKL1 AK5 AK5 CTPS2 CTPS2 NTHL1 NTHL1 AK3 AK3 NME3 NME3 NME5 NME5 NME4 NME4 CDA CDA CMPK1-2 CMPK1-2 TYMS TYMS TDG TDG DUT DUT MBD4 MBD4 APOBEC1 APOBEC1 APOBEC2 APOBEC2 UPP1 UPP1 DPYS DPYS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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OGG18-oxoguanine DNA glycosylase. (414 aa)
CDADC1Cytidine and dCMP deaminase domain containing 1. (497 aa)
CADCarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (2200 aa)
ACPPAcid phosphatase, prostate; Belongs to the histidine acid phosphatase family. (418 aa)
ERHEnhancer of rudimentary homolog; May have a role in the cell cycle. (104 aa)
UNGUracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family. (313 aa)
UPP2Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (363 aa)
UMPSUridine monophosphate synthetase. (481 aa)
NT5C5', 3'-nucleotidase, cytosolic. (201 aa)
TET3Tet methylcytosine dioxygenase 3. (1760 aa)
ENSNLEP00000049179Uncharacterized protein. (80 aa)
TK2Thymidine kinase 2. (296 aa)
LOC100582337Nucleoside diphosphate kinase. (147 aa)
CMPK2Thymidylate_kin domain-containing protein. (379 aa)
APOBEC3CCMP/dCMP-type deaminase domain-containing protein. (190 aa)
UPB1Beta-ureidopropionase 1. (384 aa)
ENTPD4Ectonucleoside triphosphate diphosphohydrolase 4; Belongs to the GDA1/CD39 NTPase family. (617 aa)
UPRTUncharacterized protein. (173 aa)
ENTPD7Ectonucleoside triphosphate diphosphohydrolase 7; Belongs to the GDA1/CD39 NTPase family. (604 aa)
ALDH6A1Aldehyde dehydrogenase 6 family member A1. (535 aa)
UNG-2Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family. (313 aa)
ENSNLEP00000041001dUTPase domain-containing protein. (155 aa)
TKTL2Transket_pyr domain-containing protein. (722 aa)
ENSNLEP00000036501Uncharacterized protein. (326 aa)
NME6Nucleoside diphosphate kinase. (194 aa)
DCKdNK domain-containing protein. (317 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2578 aa)
DHODHDihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (395 aa)
TPK1Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family. (233 aa)
ENSNLEP00000031350Uncharacterized protein. (283 aa)
ENSNLEP00000030795Thymidylate_kin domain-containing protein. (224 aa)
AICDAActivation induced cytidine deaminase. (202 aa)
ENSNLEP00000030516Thymidine kinase. (240 aa)
NME1-NME2Nucleoside diphosphate kinase. (292 aa)
LOC100604176Transket_pyr domain-containing protein. (320 aa)
DCTDdCMP deaminase. (178 aa)
APOBEC3DUncharacterized protein. (365 aa)
CPS1Carbamoyl-phosphate synthase 1. (1506 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (341 aa)
NME9NME/NM23 family member 9; Belongs to the NDK family. (330 aa)
SMUG1Single-strand-selective monofunctional uracil-DNA glycosylase 1. (270 aa)
CMPK1UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (228 aa)
ENTPD5Ectonucleoside triphosphate diphosphohydrolase 5 (inactive); Belongs to the GDA1/CD39 NTPase family. (428 aa)
ZBTB49Zinc finger and BTB domain containing 49. (766 aa)
DCTPP1dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism. (170 aa)
NT5C3A5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (336 aa)
APOBEC3HCMP/dCMP-type deaminase domain-containing protein. (211 aa)
APOBEC3AUncharacterized protein. (486 aa)
THTPAThiamine-triphosphatase; Hydrolase highly specific for thiamine triphosphate (ThTP). (230 aa)
SLC19A2Solute carrier family 19 member 2. (497 aa)
NME7Nucleoside diphosphate kinase 7; Belongs to the NDK family. (376 aa)
UCK2Uridine-cytidine kinase 2. (228 aa)
TBPL1TATA-box binding protein like 1. (186 aa)
ENPP3Ectonucleotide pyrophosphatase/phosphodiesterase 3. (874 aa)
TKTL1Transketolase like 1. (569 aa)
G1RT41_NOMLEUncharacterized protein. (154 aa)
SLC19A3Solute carrier family 19 member 3. (426 aa)
TET2Tet methylcytosine dioxygenase 2. (2001 aa)
NEIL1FPG_CAT domain-containing protein. (145 aa)
UCK1Uridine-cytidine kinase 1. (281 aa)
CTPS1CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (591 aa)
TET1Tet methylcytosine dioxygenase 1. (2136 aa)
DPYDDihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (1025 aa)
LOC100596171Uncharacterized protein. (143 aa)
UCKL1Uridine-cytidine kinase; Belongs to the uridine kinase family. (539 aa)
AK5Adenylate kinase 5; Belongs to the adenylate kinase family. (562 aa)
CTPS2CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (586 aa)
NTHL1Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (312 aa)
AK3GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (223 aa)
NME3Nucleoside diphosphate kinase. (169 aa)
NME5NME/NM23 family member 5; Belongs to the NDK family. (212 aa)
NME4Nucleoside diphosphate kinase. (187 aa)
CDACytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (146 aa)
CMPK1-2UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (228 aa)
TYMSThymidylat_synt domain-containing protein. (173 aa)
TDGThymine DNA glycosylase. (408 aa)
DUTDeoxyuridine triphosphatase. (237 aa)
MBD4Methyl-CpG-binding domain protein 4; Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein. (578 aa)
APOBEC1Apolipoprotein B mRNA editing enzyme catalytic subunit 1. (236 aa)
APOBEC2Apolipoprotein B mRNA editing enzyme catalytic subunit 2. (224 aa)
UPP1Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (310 aa)
DPYSDihydropyrimidinase. (519 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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