STRINGSTRING
RYR2 RYR2 ADRA1A ADRA1A CLIC2 CLIC2 ITGA2 ITGA2 ENSNLEP00000041886 ENSNLEP00000041886 SMAD3 SMAD3 BECN1 BECN1 DSP DSP ZC3H12A ZC3H12A TACR2 TACR2 DOCK4 DOCK4 JUP JUP PI16 PI16 TNNI3 TNNI3 TNNI1 TNNI1 MYH7 MYH7 GATA4 GATA4 ATP1B1 ATP1B1 CACNA2D1 CACNA2D1 ADORA2B ADORA2B PDE9A PDE9A MYBPC3 MYBPC3 CCN2 CCN2 G6PD G6PD HCN4 HCN4 PARP1 PARP1 MTPN MTPN CASQ1 CASQ1 HDAC4 HDAC4 TNNT3 TNNT3 TACR3 TACR3 TOMM70 TOMM70 TBXA2R TBXA2R SPHK1 SPHK1 DMPK DMPK TRPV4 TRPV4 CALCA CALCA KCNB2 KCNB2 FOXO1 FOXO1 JARID2 JARID2 MYL5 MYL5 ARHGAP42 ARHGAP42 SUMO1 SUMO1 LMNA LMNA SLC8A3 SLC8A3 FBXO32 FBXO32 MYOCD MYOCD LOC100606903 LOC100606903 ENSNLEP00000047564 ENSNLEP00000047564 ATP1A2 ATP1A2 AIF1 AIF1 SMAD7 SMAD7 OXTR OXTR MYL3 MYL3 SRI SRI SCN4A SCN4A FKBP1B FKBP1B EDN1 EDN1 CACNB1 CACNB1 RPS6KB1 RPS6KB1 MYL2 MYL2 NKX2-5 NKX2-5 NOS1 NOS1 PRKCA PRKCA CACNG1 CACNG1 SCN5A SCN5A NR4A1 NR4A1 PTGS2 PTGS2 RGS2 RGS2 CACNA1S CACNA1S LOC100592546 LOC100592546 MYOG MYOG MYBPH MYBPH ATP2B4 ATP2B4 CHRM3 CHRM3 NEUROG1 NEUROG1 ADRA2C ADRA2C KCNA1 KCNA1 GLRX3 GLRX3 ANKRD44 ANKRD44 GPER1 GPER1 ASPH ASPH ENSNLEP00000025216 ENSNLEP00000025216 MEF2A MEF2A PRKACA PRKACA TNNT2 TNNT2 TACR1 TACR1 PDE4B PDE4B ATP2B1 ATP2B1 PLN PLN PDE4D PDE4D ENSNLEP00000028440 ENSNLEP00000028440 TNNI2 TNNI2 DLG1 DLG1 KCNJ2 KCNJ2 CALM1 CALM1 TNFRSF1A TNFRSF1A KCNMA1 KCNMA1 SLC8A1 SLC8A1 LOC100582441 LOC100582441 CHRM2 CHRM2 GTF2IRD1 GTF2IRD1 ADA ADA STRIT1 STRIT1 TNNC2 TNNC2 HAND2 HAND2 CALCRL CALCRL DSG2 DSG2 GRK2 GRK2 GUCY1A1 GUCY1A1 TMEM38A TMEM38A GHSR GHSR PAWR PAWR HRC HRC CASQ2 CASQ2 GHRL GHRL ANKRD66 ANKRD66 ADRA1B ADRA1B SRF SRF NOS3 NOS3 CAV3 CAV3 LMCD1 LMCD1 CAMK2B CAMK2B SOD1 SOD1 MLIP MLIP UCN UCN AKAP6 AKAP6 DAPK3 DAPK3 PPP3CA PPP3CA YY1 YY1 ENSNLEP00000031915 ENSNLEP00000031915 RANGRF RANGRF CAV1 CAV1 GJA5 GJA5 TPM1 TPM1 SLN SLN TRPC3 TRPC3 CACNA1C CACNA1C TRIM63 TRIM63 PDE5A PDE5A SGCA SGCA PRKAG3 PRKAG3 ASB3 ASB3 PIK3CG PIK3CG ERRFI1 ERRFI1 CHRNB4 CHRNB4 CHRNA3 CHRNA3 NMU NMU KIT KIT CTDP1 CTDP1 NOTCH1 NOTCH1 OXT OXT IGFBP5 IGFBP5 TNNC1 TNNC1 DAG1 DAG1 RHOA RHOA ACE2 ACE2 SLC9A1 SLC9A1 ZDHHC21 ZDHHC21 CDK9 CDK9 TMEM38B TMEM38B P2RX1 P2RX1 CHGA CHGA NR4A3 NR4A3 CAMK2G CAMK2G PKP2 PKP2 LOC100592286 LOC100592286 MYLK2 MYLK2 PTAFR PTAFR TNFRSF1B TNFRSF1B BMP10 BMP10 ABAT ABAT RNF207 RNF207 CTTN CTTN ATP2A2 ATP2A2 GSK3A GSK3A PARP2 PARP2 ABCC8 ABCC8 CAMK2D CAMK2D ATP2A1 ATP2A1 ORMDL3 ORMDL3 ADRA2B ADRA2B ACTN3 ACTN3 TRPM4 TRPM4 ANXA6 ANXA6 PPARG PPARG ENSNLEP00000036737 ENSNLEP00000036737 SETD3 SETD3 ENSNLEP00000035899 ENSNLEP00000035899 ROCK2 ROCK2 ENSNLEP00000035652 ENSNLEP00000035652 TIFAB TIFAB PVALEF PVALEF MYL9 MYL9 SPX SPX DSC2 DSC2 FOXP1 FOXP1 NMUR2 NMUR2 ANK2 ANK2 STC1 STC1 GATA5 GATA5 PPARA PPARA BIN1 BIN1 EHD3 EHD3 GSTO1 GSTO1 AKAP9 AKAP9 DMD DMD SSTR2 SSTR2 ATP1A1 ATP1A1 MYMK MYMK PLCE1 PLCE1 CMYA5 CMYA5 F2R F2R CNN1 CNN1 EDN2 EDN2 CTNNA3 CTNNA3 PRKG1 PRKG1 SMAD4 SMAD4 SCN10A SCN10A IGF1 IGF1 ANKRD28 ANKRD28 PROK2 PROK2 P2RX4 P2RX4 ROCK1 ROCK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RYR2Ryanodine receptor 2. (4825 aa)
ADRA1AAdrenoceptor alpha 1A. (470 aa)
CLIC2Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (243 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1181 aa)
ENSNLEP00000041886Ion_trans domain-containing protein; Belongs to the potassium channel family. (359 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
BECN1Beclin 1. (450 aa)
DSPDesmoplakin. (2817 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (560 aa)
TACR2Tachykinin receptor 2; Belongs to the G-protein coupled receptor 1 family. (393 aa)
DOCK4Dedicator of cytokinesis 4; Belongs to the DOCK family. (2019 aa)
JUPJunction plakoglobin. (730 aa)
PI16Peptidase inhibitor 16; Belongs to the CRISP family. (463 aa)
TNNI3Troponin I3, cardiac type. (210 aa)
TNNI1Troponin I1, slow skeletal type. (187 aa)
MYH7Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1899 aa)
GATA4GATA binding protein 4. (443 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1071 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (329 aa)
PDE9APhosphodiesterase. (542 aa)
MYBPC3Uncharacterized protein. (789 aa)
CCN2Cellular communication network factor 2. (349 aa)
G6PDUncharacterized protein. (452 aa)
HCN4Cyclic nucleotide-binding domain-containing protein. (754 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (948 aa)
MTPNMyotrophin. (118 aa)
CASQ1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (121 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1051 aa)
TNNT3Uncharacterized protein. (172 aa)
TACR3Tachykinin receptor 3; Belongs to the G-protein coupled receptor 1 family. (465 aa)
TOMM70Translocase of outer mitochondrial membrane 70. (608 aa)
TBXA2RThromboxane A2 receptor; Belongs to the G-protein coupled receptor 1 family. (407 aa)
SPHK1DAGKc domain-containing protein. (398 aa)
DMPKDM1 protein kinase. (630 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (846 aa)
CALCACalcitonin related polypeptide alpha. (141 aa)
KCNB2Potassium voltage-gated channel subfamily B member 2; Belongs to the potassium channel family. (911 aa)
FOXO1Forkhead box O1. (652 aa)
JARID2Jumonji and AT-rich interaction domain containing 2. (1225 aa)
MYL5Myosin light chain 5. (182 aa)
ARHGAP42Rho GTPase activating protein 42. (867 aa)
SUMO1Small ubiquitin-related modifier. (88 aa)
LMNALamin A/C; Belongs to the intermediate filament family. (664 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (927 aa)
FBXO32F-box protein 32. (371 aa)
MYOCDMyocardin. (986 aa)
LOC100606903Uncharacterized protein; Belongs to the GST superfamily. (236 aa)
ENSNLEP00000047564Uncharacterized protein. (204 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
AIF1Allograft inflammatory factor 1. (161 aa)
SMAD7Mothers against decapentaplegic homolog. (376 aa)
OXTROxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (389 aa)
MYL3EF-hand domain-containing protein. (161 aa)
SRISorcin. (221 aa)
SCN4ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1848 aa)
FKBP1BPeptidylprolyl isomerase. (108 aa)
EDN1Endothelin 1. (211 aa)
CACNB1Calcium voltage-gated channel auxiliary subunit beta 1. (586 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (513 aa)
MYL2Myosin light chain 2. (166 aa)
NKX2-5NK2 homeobox 5. (317 aa)
NOS1Nitric oxide synthase; Produces nitric oxide (NO). (1425 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (222 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1925 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1. (589 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
RGS2Regulator of G protein signaling 2. (211 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1679 aa)
LOC100592546ANK_REP_REGION domain-containing protein. (515 aa)
MYOGMyogenin. (249 aa)
MYBPHMyosin binding protein H. (437 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1241 aa)
CHRM3Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (590 aa)
NEUROG1Neurogenin 1. (237 aa)
ADRA2CG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (374 aa)
KCNA1Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family. (495 aa)
GLRX3Uncharacterized protein. (335 aa)
ANKRD44Ankyrin repeat domain 44. (993 aa)
GPER1G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (377 aa)
ASPHAspartate beta-hydroxylase. (762 aa)
ENSNLEP00000025216Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (256 aa)
MEF2AMyocyte enhancer factor 2A. (509 aa)
PRKACAProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (294 aa)
TNNT2Uncharacterized protein. (339 aa)
TACR1Tachykinin receptor 1. (406 aa)
PDE4BPhosphodiesterase. (736 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1258 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
PDE4DPhosphodiesterase. (748 aa)
ENSNLEP00000028440Uncharacterized protein. (95 aa)
TNNI2Troponin I2, fast skeletal type. (182 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (916 aa)
KCNJ2Potassium voltage-gated channel subfamily J member 2. (427 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (150 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1289 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (972 aa)
LOC100582441Uncharacterized protein. (826 aa)
CHRM2Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (466 aa)
GTF2IRD1GTF2I repeat domain containing 1. (925 aa)
ADAAdenosine deaminase. (405 aa)
STRIT1Small transmembrane regulator of ion transport 1. (35 aa)
TNNC2Troponin C2, fast skeletal type. (160 aa)
HAND2Heart and neural crest derivatives expressed 2. (198 aa)
CALCRLCalcitonin receptor like receptor; Belongs to the G-protein coupled receptor 2 family. (461 aa)
DSG2Desmoglein 2. (1098 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (589 aa)
GUCY1A1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
TMEM38ATransmembrane protein 38A. (299 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
PAWRPro-apoptotic WT1 regulator. (340 aa)
HRCHistidine rich calcium binding protein. (696 aa)
CASQ2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (373 aa)
GHRLGhrelin and obestatin prepropeptide. (117 aa)
ANKRD66Ankyrin repeat domain 66. (251 aa)
ADRA1BG_PROTEIN_RECEP_F1_2 domain-containing protein. (384 aa)
SRFSerum response factor. (508 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1128 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
LMCD1LIM and cysteine rich domains 1. (345 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (607 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
MLIPMuscular LMNA interacting protein. (994 aa)
UCNUrocortin. (124 aa)
AKAP6A-kinase anchoring protein 6. (2238 aa)
DAPK3Death associated protein kinase 3. (407 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
YY1Uncharacterized protein. (311 aa)
ENSNLEP00000031915Ubiquitin-like domain-containing protein. (93 aa)
RANGRFRAN guanine nucleotide release factor. (186 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
TPM1Uncharacterized protein; Belongs to the tropomyosin family. (326 aa)
SLNSarcolipin. (31 aa)
TRPC3Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (921 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1985 aa)
TRIM63Tripartite motif containing 63. (333 aa)
PDE5APhosphodiesterase. (875 aa)
SGCASarcoglycan alpha. (387 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (489 aa)
ASB3Ankyrin repeat and SOCS box containing 3. (549 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa)
ERRFI1ERBB receptor feedback inhibitor 1. (462 aa)
CHRNB4Cholinergic receptor nicotinic beta 4 subunit. (448 aa)
CHRNA3Cholinergic receptor nicotinic alpha 3 subunit. (503 aa)
NMUNeuromedin U. (173 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (969 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (951 aa)
NOTCH1Notch receptor 1. (2451 aa)
OXTOxytocin/neurophysin I prepropeptide; Belongs to the vasopressin/oxytocin family. (124 aa)
IGFBP5Insulin like growth factor binding protein 5. (272 aa)
TNNC1Troponin C1, slow skeletal and cardiac type. (161 aa)
DAG1Dystroglycan 1. (895 aa)
RHOARas homolog family member A. (193 aa)
ACE2Angiotensin-converting enzyme. (805 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (809 aa)
ZDHHC21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
CDK9Cyclin dependent kinase 9. (372 aa)
TMEM38BTransmembrane protein 38B. (291 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (379 aa)
CHGAChromogranin A. (460 aa)
NR4A3Nuclear receptor subfamily 4 group A member 3. (636 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (524 aa)
PKP2Uncharacterized protein. (841 aa)
LOC100592286Uncharacterized protein. (818 aa)
MYLK2Myosin light chain kinase 2. (596 aa)
PTAFRPlatelet activating factor receptor; Belongs to the G-protein coupled receptor 1 family. (342 aa)
TNFRSF1BTNF receptor superfamily member 1B. (424 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
ABAT4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (516 aa)
RNF207Ring finger protein 207. (634 aa)
CTTNSH3 domain-containing protein. (549 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
GSK3AGlycogen synthase kinase 3 alpha. (439 aa)
PARP2Poly [ADP-ribose] polymerase. (583 aa)
ABCC8ATP binding cassette subfamily C member 8. (1569 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (533 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1031 aa)
ORMDL3ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
ADRA2BG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (391 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (922 aa)
TRPM4Uncharacterized protein. (1010 aa)
ANXA6Annexin. (673 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
ENSNLEP00000036737Uncharacterized protein. (160 aa)
SETD3Protein-histidine N-methyltransferase. (595 aa)
ENSNLEP00000035899Uncharacterized protein. (321 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa)
ENSNLEP00000035652Uncharacterized protein; Belongs to the calmodulin family. (123 aa)
TIFABTIFA inhibitor. (162 aa)
PVALEFParvalbumin like EF-hand containing. (134 aa)
MYL9Myosin light chain 9. (172 aa)
SPXSpexin hormone. (116 aa)
DSC2Desmocollin 2; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (859 aa)
FOXP1Forkhead box P1. (693 aa)
NMUR2Neuromedin U receptor 2; Belongs to the G-protein coupled receptor 1 family. (403 aa)
ANK2Ankyrin 2. (3957 aa)
STC1Stanniocalcin 1. (247 aa)
GATA5GATA binding protein 5. (363 aa)
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
BIN1Bridging integrator 1. (582 aa)
EHD3EH domain containing 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (478 aa)
GSTO1Glutathione S-transferase omega 1. (241 aa)
AKAP9A-kinase anchoring protein 9. (3896 aa)
DMDDystrophin. (3685 aa)
SSTR2Somatostatin receptor 2; Belongs to the G-protein coupled receptor 1 family. (369 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1027 aa)
MYMKUncharacterized protein. (127 aa)
PLCE1Phosphoinositide phospholipase C. (2303 aa)
CMYA5Cardiomyopathy associated 5. (3982 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (425 aa)
CNN1Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (304 aa)
EDN2Endothelin 2. (177 aa)
CTNNA3Catenin alpha 3. (895 aa)
PRKG1cGMP-dependent protein kinase. (686 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
SCN10ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1959 aa)
IGF1IlGF domain-containing protein. (196 aa)
ANKRD28Ankyrin repeat domain 28. (1063 aa)
PROK2Prokineticin 2. (129 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (404 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1359 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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