STRINGSTRING
AMPD2 AMPD2 NR1D2 NR1D2 ENSNLEP00000028071 ENSNLEP00000028071 DLL1 DLL1 ENSNLEP00000030707 ENSNLEP00000030707 IRX3 IRX3 PRKAA1 PRKAA1 MEX3C MEX3C ENSNLEP00000035481 ENSNLEP00000035481 EIF4G1 EIF4G1 PASK PASK CRTC3 CRTC3 PPARGC1A PPARGC1A CD36 CD36 TSKU TSKU LEPR LEPR CRTC1 CRTC1 RRP8 RRP8 NR4A3 NR4A3 ALK ALK SGIP1 SGIP1 FMO4 FMO4 FMO1 FMO1 FMO2 FMO2 SLC35D3 SLC35D3 OMA1 OMA1 PRKAA2 PRKAA2 PM20D1 PM20D1 FLCN FLCN MRAP2 MRAP2 EDN2 EDN2 SIRT1 SIRT1 STAT3 STAT3 NMU NMU PIK3CA PIK3CA FOXO1 FOXO1 ACACB ACACB TRPV4 TRPV4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AMPD2AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (879 aa)
NR1D2Nuclear receptor subfamily 1 group D member 2. (580 aa)
ENSNLEP00000028071BHLH domain-containing protein. (606 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (737 aa)
ENSNLEP00000030707Uncharacterized protein. (159 aa)
IRX3Iroquois homeobox 3. (476 aa)
PRKAA1Non-specific serine/threonine protein kinase. (574 aa)
MEX3CRING-type domain-containing protein. (478 aa)
ENSNLEP00000035481Uncharacterized protein. (73 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1. (1558 aa)
PASKPAS domain containing serine/threonine kinase. (1323 aa)
CRTC3CREB regulated transcription coactivator 3. (575 aa)
PPARGC1APPARG coactivator 1 alpha. (801 aa)
CD36CD36 molecule; Belongs to the CD36 family. (433 aa)
TSKUTsukushi, small leucine rich proteoglycan. (354 aa)
LEPRLeptin receptor. (1165 aa)
CRTC1CREB regulated transcription coactivator 1. (619 aa)
RRP8Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] (447 aa)
NR4A3Nuclear receptor subfamily 4 group A member 3. (636 aa)
ALKUncharacterized protein. (1134 aa)
SGIP1MHD domain-containing protein. (768 aa)
FMO4Dimethylaniline monooxygenase [N-oxide-forming]. (558 aa)
FMO1Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa)
FMO2Dimethylaniline monooxygenase [N-oxide-forming]. (535 aa)
SLC35D3Solute carrier family 35 member D3. (416 aa)
OMA1OMA1 zinc metallopeptidase. (524 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
PM20D1Peptidase M20 domain containing 1. (500 aa)
FLCNFolliculin. (542 aa)
MRAP2Melanocortin 2 receptor accessory protein 2. (205 aa)
EDN2Endothelin 2. (177 aa)
SIRT1Sirtuin 1. (734 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
NMUNeuromedin U. (173 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
FOXO1Forkhead box O1. (652 aa)
ACACBAcetyl-CoA carboxylase beta. (2410 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (846 aa)
Your Current Organism:
Nomascus leucogenys
NCBI taxonomy Id: 61853
Other names: Hylobates concolor leucogenys, Hylobates concolor leucogyneus, Hylobates leucogenys, Hylobates leucogenys leucogenys, N. leucogenys, Nomascus leucogenys leucogenys, Nomascus leukogenys, White-cheeked Gibbon, northern white-cheeked gibbon
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